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Evolutionary analyses of the human genome

Author

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  • Wen-Hsiung Li

    (Ecology and Evolution, University of Chicago)

  • Zhenglong Gu

    (Ecology and Evolution, University of Chicago)

  • Haidong Wang

    (Ecology and Evolution, University of Chicago)

  • Anton Nekrutenko

    (Ecology and Evolution, University of Chicago)

Abstract

The completion of the human genome will greatly accelerate the development of a new branch of science—evolutionary genomics. We can now directly address important questions about the evolutionary history of human genes and their regulatory sequences. Computational analyses of the human genome will reveal the number of genes and repetitive elements, the extent of gene duplication and compositional heterogeneity in the human genome, and the extent of domain shuffling and domain sharing among proteins. Here we present some first glimpses of these features.

Suggested Citation

  • Wen-Hsiung Li & Zhenglong Gu & Haidong Wang & Anton Nekrutenko, 2001. "Evolutionary analyses of the human genome," Nature, Nature, vol. 409(6822), pages 847-849, February.
  • Handle: RePEc:nat:nature:v:409:y:2001:i:6822:d:10.1038_35057039
    DOI: 10.1038/35057039
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    Cited by:

    1. Obubu Maxwell* & Ikediuwa Udoka Chinedu & Anabike Charles Ifeanyi, 2019. "Numbers in Life: A Statistical Genetic Approach," Scientific Review, Academic Research Publishing Group, vol. 5(7), pages 142-149, 07-2019.

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