IDEAS home Printed from https://ideas.repec.org/a/nat/nathum/v4y2020i9d10.1038_s41562-020-00944-2.html
   My bibliography  Save this article

Population-scale longitudinal mapping of COVID-19 symptoms, behaviour and testing

Author

Listed:
  • William E. Allen

    (The How We Feel Project
    Harvard University
    Broad Institute of MIT and Harvard)

  • Han Altae-Tran

    (The How We Feel Project
    Broad Institute of MIT and Harvard
    Massachusetts Institute of Technology)

  • James Briggs

    (The How We Feel Project
    Broad Institute of MIT and Harvard
    Schmidt Science Fellows)

  • Xin Jin

    (The How We Feel Project
    Harvard University
    Broad Institute of MIT and Harvard)

  • Glen McGee

    (The How We Feel Project
    Harvard T.H. Chan School of Public Health)

  • Andy Shi

    (The How We Feel Project
    Harvard T.H. Chan School of Public Health)

  • Rumya Raghavan

    (The How We Feel Project
    Broad Institute of MIT and Harvard
    Health Sciences and Technology Program, Massachusetts Institute of Technology and Harvard Medical School)

  • Mireille Kamariza

    (The How We Feel Project
    Harvard University
    Broad Institute of MIT and Harvard)

  • Nicole Nova

    (The How We Feel Project
    Stanford University)

  • Albert Pereta

    (The How We Feel Project)

  • Chris Danford

    (The How We Feel Project)

  • Amine Kamel

    (The How We Feel Project)

  • Patrik Gothe

    (The How We Feel Project)

  • Evrhet Milam

    (The How We Feel Project)

  • Jean Aurambault

    (The How We Feel Project)

  • Thorben Primke

    (The How We Feel Project)

  • Weijie Li

    (The How We Feel Project)

  • Josh Inkenbrandt

    (The How We Feel Project)

  • Tuan Huynh

    (The How We Feel Project)

  • Evan Chen

    (The How We Feel Project)

  • Christina Lee

    (The How We Feel Project)

  • Michael Croatto

    (The How We Feel Project)

  • Helen Bentley

    (The How We Feel Project)

  • Wendy Lu

    (The How We Feel Project)

  • Robert Murray

    (The How We Feel Project)

  • Mark Travassos

    (The How We Feel Project
    University of Maryland School of Medicine)

  • Brent A. Coull

    (Harvard T.H. Chan School of Public Health)

  • John Openshaw

    (The How We Feel Project
    Stanford University School of Medicine)

  • Casey S. Greene

    (The How We Feel Project
    University of Pennsylvania Perelman School of Medicine)

  • Ophir Shalem

    (The How We Feel Project
    University of Pennsylvania Perelman School of Medicine)

  • Gary King

    (The How We Feel Project
    Harvard University)

  • Ryan Probasco

    (The How We Feel Project)

  • David R. Cheng

    (The How We Feel Project)

  • Ben Silbermann

    (The How We Feel Project)

  • Feng Zhang

    (The How We Feel Project
    Broad Institute of MIT and Harvard
    Massachusetts Institute of Technology
    McGovern Institute for Brain Research, Massachusetts Institute of Technology)

  • Xihong Lin

    (The How We Feel Project
    Broad Institute of MIT and Harvard
    Harvard T.H. Chan School of Public Health
    Harvard University)

Abstract

Despite the widespread implementation of public health measures, coronavirus disease 2019 (COVID-19) continues to spread in the United States. To facilitate an agile response to the pandemic, we developed How We Feel, a web and mobile application that collects longitudinal self-reported survey responses on health, behaviour and demographics. Here, we report results from over 500,000 users in the United States from 2 April 2020 to 12 May 2020. We show that self-reported surveys can be used to build predictive models to identify likely COVID-19-positive individuals. We find evidence among our users for asymptomatic or presymptomatic presentation; show a variety of exposure, occupational and demographic risk factors for COVID-19 beyond symptoms; reveal factors for which users have been SARS-CoV-2 PCR tested; and highlight the temporal dynamics of symptoms and self-isolation behaviour. These results highlight the utility of collecting a diverse set of symptomatic, demographic, exposure and behavioural self-reported data to fight the COVID-19 pandemic.

Suggested Citation

  • William E. Allen & Han Altae-Tran & James Briggs & Xin Jin & Glen McGee & Andy Shi & Rumya Raghavan & Mireille Kamariza & Nicole Nova & Albert Pereta & Chris Danford & Amine Kamel & Patrik Gothe & Evr, 2020. "Population-scale longitudinal mapping of COVID-19 symptoms, behaviour and testing," Nature Human Behaviour, Nature, vol. 4(9), pages 972-982, September.
  • Handle: RePEc:nat:nathum:v:4:y:2020:i:9:d:10.1038_s41562-020-00944-2
    DOI: 10.1038/s41562-020-00944-2
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41562-020-00944-2
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.

    File URL: https://libkey.io/10.1038/s41562-020-00944-2?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Peng Zhou & Xing-Lou Yang & Xian-Guang Wang & Ben Hu & Lei Zhang & Wei Zhang & Hao-Rui Si & Yan Zhu & Bei Li & Chao-Lin Huang & Hui-Dong Chen & Jing Chen & Yun Luo & Hua Guo & Ren-Di Jiang & Mei-Qin L, 2020. "Addendum: A pneumonia outbreak associated with a new coronavirus of probable bat origin," Nature, Nature, vol. 588(7836), pages 6-6, December.
    2. Peng Zhou & Xing-Lou Yang & Xian-Guang Wang & Ben Hu & Lei Zhang & Wei Zhang & Hao-Rui Si & Yan Zhu & Bei Li & Chao-Lin Huang & Hui-Dong Chen & Jing Chen & Yun Luo & Hua Guo & Ren-Di Jiang & Mei-Qin L, 2020. "A pneumonia outbreak associated with a new coronavirus of probable bat origin," Nature, Nature, vol. 579(7798), pages 270-273, March.
    3. Amy Maxmen, 2020. "Thousands of coronavirus tests are going unused in US labs," Nature, Nature, vol. 580(7803), pages 312-313, April.
    4. Smolinski, M.S. & Crawley, A.W. & Baltrusaitis, K. & Chunara, R. & Olsen, J.M. & Wójcik, O. & Santillana, M. & Nguyen, A. & Brownstein, J.S., 2015. "Flu near you: Crowdsourced symptom reporting spanning 2 influenza seasons," American Journal of Public Health, American Public Health Association, vol. 105(10), pages 2124-2130.
    5. Toomet, Ott & Henningsen, Arne, 2008. "Sample Selection Models in R: Package sampleSelection," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 27(i07).
    6. Xingjie Hao & Shanshan Cheng & Degang Wu & Tangchun Wu & Xihong Lin & Chaolong Wang, 2020. "Reconstruction of the full transmission dynamics of COVID-19 in Wuhan," Nature, Nature, vol. 584(7821), pages 420-424, August.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Younjung Kim & Christl A. Donnelly & Pierre Nouvellet, 2023. "Drivers of SARS-CoV-2 testing behaviour: a modelling study using nationwide testing data in England," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
    2. Elizabeth Dolan & James Goulding & Harry Marshall & Gavin Smith & Gavin Long & Laila J. Tata, 2023. "Assessing the value of integrating national longitudinal shopping data into respiratory disease forecasting models," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
    3. Bo Huang & Jionghua Wang & Jixuan Cai & Shiqi Yao & Paul Kay Sheung Chan & Tony Hong-wing Tam & Ying-Yi Hong & Corrine W. Ruktanonchai & Alessandra Carioli & Jessica R. Floyd & Nick W. Ruktanonchai & , 2021. "Integrated vaccination and physical distancing interventions to prevent future COVID-19 waves in Chinese cities," Nature Human Behaviour, Nature, vol. 5(6), pages 695-705, June.
    4. Jina Suh & Eric Horvitz & Ryen W. White & Tim Althoff, 2022. "Disparate impacts on online information access during the Covid-19 pandemic," Nature Communications, Nature, vol. 13(1), pages 1-15, December.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Graziella Orrù & Ciro Conversano & Eleonora Malloggi & Francesca Francesconi & Rebecca Ciacchini & Angelo Gemignani, 2020. "Neurological Complications of COVID-19 and Possible Neuroinvasion Pathways: A Systematic Review," IJERPH, MDPI, vol. 17(18), pages 1-18, September.
    2. Britton Boras & Rhys M. Jones & Brandon J. Anson & Dan Arenson & Lisa Aschenbrenner & Malina A. Bakowski & Nathan Beutler & Joseph Binder & Emily Chen & Heather Eng & Holly Hammond & Jennifer Hammond , 2021. "Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19," Nature Communications, Nature, vol. 12(1), pages 1-17, December.
    3. Yongzhu Xiong & Yunpeng Wang & Feng Chen & Mingyong Zhu, 2020. "Spatial Statistics and Influencing Factors of the COVID-19 Epidemic at Both Prefecture and County Levels in Hubei Province, China," IJERPH, MDPI, vol. 17(11), pages 1-26, May.
    4. Eugene Song & Jae-Eun Lee & Seola Kwon, 2021. "Effect of Public Empathy with Infection-Control Guidelines on Infection-Prevention Attitudes and Behaviors: Based on the Case of COVID-19," IJERPH, MDPI, vol. 18(24), pages 1-18, December.
    5. Jaeyong Lee & Calem Kenward & Liam J. Worrall & Marija Vuckovic & Francesco Gentile & Anh-Tien Ton & Myles Ng & Artem Cherkasov & Natalie C. J. Strynadka & Mark Paetzel, 2022. "X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
    6. Xu, Baochang & Li, Sihui & Afzal, Ayesha & Mirza, Nawazish & Zhang, Meng, 2022. "The impact of financial development on environmental sustainability: A European perspective," Resources Policy, Elsevier, vol. 78(C).
    7. Nur Hannani Bi Rahman & Shazmin Shareena A. Azis & Ibrahim Sipan, 2021. "COVID-19: Standard Operating Procedure Improvement For Green Office Building Using Indoor Environmental Quality," LARES lares-2021-4dqg, Latin American Real Estate Society (LARES).
    8. Eduardo Gutiérrez-Abejón & Eduardo Tamayo & Débora Martín-García & F. Javier Álvarez & Francisco Herrera-Gómez, 2020. "Clinical Profile, Treatment and Predictors during the First COVID-19 Wave: A Population-Based Registry Analysis from Castile and Leon Hospitals," IJERPH, MDPI, vol. 17(24), pages 1-15, December.
    9. Meriem Bekliz & Kenneth Adea & Pauline Vetter & Christiane S. Eberhardt & Krisztina Hosszu-Fellous & Diem-Lan Vu & Olha Puhach & Manel Essaidi-Laziosi & Sophie Waldvogel-Abramowski & Caroline Stephan , 2022. "Neutralization capacity of antibodies elicited through homologous or heterologous infection or vaccination against SARS-CoV-2 VOCs," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
    10. Maria de Lourdes Aguiar-Oliveira & Aline Campos & Aline R. Matos & Caroline Rigotto & Adriana Sotero-Martins & Paulo F. P. Teixeira & Marilda M. Siqueira, 2020. "Wastewater-Based Epidemiology (WBE) and Viral Detection in Polluted Surface Water: A Valuable Tool for COVID-19 Surveillance—A Brief Review," IJERPH, MDPI, vol. 17(24), pages 1-19, December.
    11. Daiki Yamaguchi & Odgerel Chimed-Ochir & Yui Yumiya & Eisaku Kishita & Tomoyuki Akita & Junko Tanaka & Tatsuhiko Kubo, 2024. "Potential Risk Factors to COVID-19 Severity: Comparison of SARS-CoV-2 Delta- and Omicron-Dominant Periods," IJERPH, MDPI, vol. 21(3), pages 1-11, March.
    12. Dunbar, Kwamie, 2022. "Impact of the COVID-19 event on U.S. banks’ financial soundness," Research in International Business and Finance, Elsevier, vol. 59(C).
    13. Jian Rong & Ahmed Haider & Troels E. Jeppesen & Lee Josephson & Steven H. Liang, 2023. "Radiochemistry for positron emission tomography," Nature Communications, Nature, vol. 14(1), pages 1-23, December.
    14. Cecilia A. Sánchez & Hongying Li & Kendra L. Phelps & Carlos Zambrana-Torrelio & Lin-Fa Wang & Peng Zhou & Zheng-Li Shi & Kevin J. Olival & Peter Daszak, 2022. "A strategy to assess spillover risk of bat SARS-related coronaviruses in Southeast Asia," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
    15. Sarwan Ali & Babatunde Bello & Murray Patterson, 2023. "Solvent Accessibility of Coronaviridae Spike Proteins through the Lens of Information Gain," J, MDPI, vol. 6(2), pages 1-12, April.
    16. Agata Jabłońska-Trypuć & Marcin Makuła & Maria Włodarczyk-Makuła & Elżbieta Wołejko & Urszula Wydro & Lluis Serra-Majem & Józefa Wiater, 2022. "Inanimate Surfaces as a Source of Hospital Infections Caused by Fungi, Bacteria and Viruses with Particular Emphasis on SARS-CoV-2," IJERPH, MDPI, vol. 19(13), pages 1-22, July.
    17. Yongin Choi & James Slghee Kim & Heejin Choi & Hyojung Lee & Chang Hyeong Lee, 2020. "Assessment of Social Distancing for Controlling COVID-19 in Korea: An Age-Structured Modeling Approach," IJERPH, MDPI, vol. 17(20), pages 1-16, October.
    18. Diego Fernández-Lázaro & Jerónimo J. González-Bernal & Nerea Sánchez-Serrano & Lourdes Jiménez Navascués & Ana Ascaso-del-Río & Juan Mielgo-Ayuso, 2020. "Physical Exercise as a Multimodal Tool for COVID-19: Could It Be Used as a Preventive Strategy?," IJERPH, MDPI, vol. 17(22), pages 1-13, November.
    19. Federico Alcide Villani & Riccardo Aiuto & Luigi Paglia & Dino Re, 2020. "COVID-19 and Dentistry: Prevention in Dental Practice, a Literature Review," IJERPH, MDPI, vol. 17(12), pages 1-12, June.
    20. Aishwarya Arjunan & Deanna R. Darnes & Katelynn G. Sagaser & Ashley B. Svenson, 2022. "Addressing Reproductive Healthcare Disparities through Equitable Carrier Screening: Medical Racism and Genetic Discrimination in United States’ History Highlights the Needs for Change in Obstetrical G," Societies, MDPI, vol. 12(2), pages 1-17, February.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nathum:v:4:y:2020:i:9:d:10.1038_s41562-020-00944-2. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.