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Planar photonic chips with tailored angular transmission for high-contrast-imaging devices

Author

Listed:
  • Yan Kuai

    (University of Science and Technology of China)

  • Junxue Chen

    (Guilin University of Technology)

  • Zetao Fan

    (University of Science and Technology of China)

  • Gang Zou

    (University of Science and Technology of China)

  • Joseph. R. Lakowicz

    (University of Maryland School of Medicine)

  • Douguo Zhang

    (University of Science and Technology of China)

Abstract

A limitation of standard brightfield microscopy is its low contrast images, especially for thin specimens of weak absorption, and biological species with refractive indices very close in value to that of their surroundings. We demonstrate, using a planar photonic chip with tailored angular transmission as the sample substrate, a standard brightfield microscopy can provide both darkfield and total internal reflection (TIR) microscopy images with one experimental configuration. The image contrast is enhanced without altering the specimens and the microscope configurations. This planar chip consists of several multilayer sections with designed photonic band gaps and a central region with dielectric nanoparticles, which does not require top-down nanofabrication and can be fabricated in a larger scale. The photonic chip eliminates the need for a bulky condenser or special objective to realize darkfield or TIR illumination. Thus, it can work as a miniaturized high-contrast-imaging device for the developments of versatile and compact microscopes.

Suggested Citation

  • Yan Kuai & Junxue Chen & Zetao Fan & Gang Zou & Joseph. R. Lakowicz & Douguo Zhang, 2021. "Planar photonic chips with tailored angular transmission for high-contrast-imaging devices," Nature Communications, Nature, vol. 12(1), pages 1-9, December.
  • Handle: RePEc:nat:natcom:v:12:y:2021:i:1:d:10.1038_s41467-021-27231-6
    DOI: 10.1038/s41467-021-27231-6
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    References listed on IDEAS

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    1. Florian O. Fahrbach & Alexander Rohrbach, 2012. "Propagation stability of self-reconstructing Bessel beams enables contrast-enhanced imaging in thick media," Nature Communications, Nature, vol. 3(1), pages 1-8, January.
    2. Ryohei Yasuda & Hiroyuki Noji & Masasuke Yoshida & Kazuhiko Kinosita & Hiroyasu Itoh, 2001. "Resolution of distinct rotational substeps by submillisecond kinetic analysis of F1-ATPase," Nature, Nature, vol. 410(6831), pages 898-904, April.
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    Cited by:

    1. Yang Liu & Mingchuan Huang & Qiankun Chen & Douguo Zhang, 2022. "Single planar photonic chip with tailored angular transmission for multiple-order analog spatial differentiator," Nature Communications, Nature, vol. 13(1), pages 1-9, December.

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