IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v10y2019i1d10.1038_s41467-019-09163-4.html
   My bibliography  Save this article

A highly selective and recyclable NO-responsive nanochannel based on a spiroring opening−closing reaction strategy

Author

Listed:
  • Yao Sun

    (Central China Normal University)

  • Sen Chen

    (Central China Normal University)

  • Xiaoya Chen

    (Hunan University)

  • Yuling Xu

    (Central China Normal University)

  • Siyun Zhang

    (Central China Normal University)

  • Qingying Ouyang

    (Central China Normal University)

  • Guangfu Yang

    (Central China Normal University)

  • Haibing Li

    (Central China Normal University)

Abstract

Endogenous nitric oxide (NO) is an important messenger molecule, which can directly activate K+ transmission and cause relaxation of vascular smooth muscle. Here, inspired by the K+ channel of smooth muscle cells, we report, a novel NO-regulated artificial nanochannel based on a spiro ring opening−closing reaction strategy. This nanofluidic diode system shows an outstanding NO selective response owing to the specific reaction between o-phenylenediamine (OPD) and NO on the channel surface with high ion rectification ratio (~6.7) and ion gating ratio (~4). Moreover, this NO gating system exhibits excellent reversibility and stability as well as high selectivity response. This system not only helps us understand the process of NO directly regulating biological ion channels, but also has potential application value in the field of biosensors.

Suggested Citation

  • Yao Sun & Sen Chen & Xiaoya Chen & Yuling Xu & Siyun Zhang & Qingying Ouyang & Guangfu Yang & Haibing Li, 2019. "A highly selective and recyclable NO-responsive nanochannel based on a spiroring opening−closing reaction strategy," Nature Communications, Nature, vol. 10(1), pages 1-8, December.
    • Handle: RePEc:nat:natcom:v:10:y:2019:i:1:d:10.1038_s41467-019-09163-4
    DOI: 10.1038/s41467-019-09163-4
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-019-09163-4
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/s41467-019-09163-4?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Dan Zhang & Yongjie Sun & Zhichao Wang & Fang Liu & Xuanjun Zhang, 2023. "Switchable biomimetic nanochannels for on-demand SO2 detection by light-controlled photochromism," Nature Communications, Nature, vol. 14(1), pages 1-11, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:10:y:2019:i:1:d:10.1038_s41467-019-09163-4. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.