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An Expert System for Drug Preformulation in a Pharmaceutical Company

Author

Listed:
  • K. V. Ramani

    (Indian Institute of Management, Ahmedabad 380 015, India)

  • M. R. Patel

    (Research and Development, Cadila Laboratories Limited, Ahmedabad 380 008, India)

  • S. K. Patel

    (Analytical Research Laboratory, Cadila Laboratories Limited, Ahmedabad 380 008, India)

Abstract

We designed, developed, and implemented a computer-based expert system for Cadila Laboratories to aid pharmaceutical experts in drug preformulations. Drugs, such as tablets, contain many chemicals (called excipients) in addition to the main active drug. A preformulation study identifies compatible excipients and their relative proportions in the final formulation. Our expert system has saved about 35 percent of the total R and D time needed for preformulations. Its success is due to the interest of top management and the excellent support of the R and D staff. It has provided a competitive advantage to Cadila Laboratories over other firms in India.

Suggested Citation

  • K. V. Ramani & M. R. Patel & S. K. Patel, 1992. "An Expert System for Drug Preformulation in a Pharmaceutical Company," Interfaces, INFORMS, vol. 22(2), pages 101-108, April.
    • Handle: RePEc:inm:orinte:v:22:y:1992:i:2:p:101-108
    DOI: 10.1287/inte.22.2.101
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    Cited by:

    1. Wong, Bo K. & Monaco, John A., 1995. "A bibliography of expert system applications for business (1984-1992)," European Journal of Operational Research, Elsevier, vol. 85(2), pages 416-432, September.

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