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Efficacy, Adherence and Side Effects of PrEP for HIV-1 Prevention

Author

Listed:
  • Wanyi Fang
  • Bongani I. Mphoyi
  • Dineo R. Motake
  • Jianxin Liu
  • Wenshuang Li
  • Fanghua Mei
  • Shenghan Lai
  • Jun Wang

Abstract

Each year, approximately two million new HIV infections are reported worldwide. About one decade ago, a company called Gilead Sciences Inc. discovered a new HIV prevention method named as pre-exposure prophylaxis (PrEP). When high adherence was kept among high-risk population, PrEP efficacy could reach as high as 99%. However, the adverse effects have been reported from time to time, including low efficacy in certain cases, adherence difficulties and medicinal side effects. In this review, we would summarize the progress of PrEP since its introduction in order to provide insights for HIV prevention.

Suggested Citation

  • Wanyi Fang & Bongani I. Mphoyi & Dineo R. Motake & Jianxin Liu & Wenshuang Li & Fanghua Mei & Shenghan Lai & Jun Wang, 2021. "Efficacy, Adherence and Side Effects of PrEP for HIV-1 Prevention," International Journal of Biology, Canadian Center of Science and Education, vol. 11(4), pages 1-80, December.
  • Handle: RePEc:ibn:ijbjnl:v:11:y:2021:i:4:p:80
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    References listed on IDEAS

    as
    1. Emiliano Rodríguez Mega, 2019. "‘Mosaic’ HIV vaccine to be tested in thousands of people across the world," Nature, Nature, vol. 572(7768), pages 165-166, August.
    2. Calabrese, S.K. & Krakower, D.S. & Mayer, K.H., 2017. "Integrating HIV preexposure prophylaxis (PrEP) into routine preventive health care to avoid exacerbating disparities," American Journal of Public Health, American Public Health Association, vol. 107(12), pages 1883-1889.
    3. Raymond A. Tetteh & Barbara A. Yankey & Edmund T. Nartey & Margaret Lartey & Hubert G. M. Leufkens & Alexander N. O. Dodoo, 2017. "Pre-Exposure Prophylaxis for HIV Prevention: Safety Concerns," Drug Safety, Springer, vol. 40(4), pages 273-283, April.
    Full references (including those not matched with items on IDEAS)

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    More about this item

    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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