IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v19y2022i19p12331-d927659.html
   My bibliography  Save this article

Increased Risk of Chronic Obstructive Pulmonary Disease in Patients with Hyperlipidemia: A Nationwide Population-Based Cohort Study

Author

Listed:
  • Hao-Yu Yang

    (Department of Family Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813414, Taiwan)

  • Li-Yu Hu

    (Department of Psychiatry, Taipei Veterans General Hospital, Taipei 112, Taiwan
    School of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan)

  • Hon-Jhe Chen

    (Department of Family Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813414, Taiwan)

  • Ru-Yih Chen

    (Department of Family Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813414, Taiwan)

  • Chang-Kuo Hu

    (Division of Neurosurgery, Department of Surgery, Chiayi Branch, Taichung Veterans General Hospital, Chiayi 600, Taiwan)

  • Cheng-Che Shen

    (School of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan
    Department of Psychiatry, Chiayi Branch, Taichung Veterans General Hospital, Chiayi 600, Taiwan)

Abstract

The coexistence of chronic obstructive pulmonary disease (COPD) and cardiovascular disease is common and causes poor prognoses. Hyperlipidemia is the most common risk factor for cardiovascular disease, but the association between hyperlipidemia and COPD remains ambiguous. This study aimed to investigate the risk of COPD development in patients with hyperlipidemia. This retrospective cohort study used information from the National Health Insurance Research Database in Taiwan. We enrolled 21,790 patients with hyperlipidemia and 87,160 control patients without hyperlipidemia for comparison, with a follow-up period of over 10 years. The incidence of new-onset COPD was higher in patients with hyperlipidemia (36.14 per 1000 person-years) than in the controls (22.29 per 1000 person-years). Patients with hyperlipidemia were 1.48 times more likely to develop subsequent COPD than the controls without hyperlipidemia (95% confidence interval 1.44 to 1.53, p < 0.001) following adjustments for age, sex, and comorbidities. In addition, nephropathy, hypertension, congestive heart failure, age, and sex (female) were potential risk factors for developing COPD in patients with hyperlipidemia. Patients with hyperlipidemia may have an increased risk of developing COPD.

Suggested Citation

  • Hao-Yu Yang & Li-Yu Hu & Hon-Jhe Chen & Ru-Yih Chen & Chang-Kuo Hu & Cheng-Che Shen, 2022. "Increased Risk of Chronic Obstructive Pulmonary Disease in Patients with Hyperlipidemia: A Nationwide Population-Based Cohort Study," IJERPH, MDPI, vol. 19(19), pages 1-11, September.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:19:p:12331-:d:927659
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/19/19/12331/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/19/19/12331/
    Download Restriction: no
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:19:y:2022:i:19:p:12331-:d:927659. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.