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Validation of the Norma Latina Neuropsychological Assessment Battery in Patients with Alzheimer’s Disease in Mexico

Author

Listed:
  • Silvia Núñez-Fernández

    (Biocruces Bizkaia Health Research Institute, 48903 Barakaldo, Spain
    Neuroscience Institute of Castilla-León, University of Salamanca, 37007 Salamanca, Spain)

  • Diego Rivera

    (Department of Health Sciences, Public University of Navarre, 31006 Pamplona, Spain
    Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008 Pamplona, Spain)

  • Eva María Arroyo-Anlló

    (Department of Psychobiology, Neuroscience Institute of Castilla-León, University of Salamanca, 37007 Salamanca, Spain)

  • Xóchitl Angélica Ortiz Jiménez

    (Faculty of Psychology, Autonomous University of Nuevo León, Monterrey 64460, Mexico)

  • Borja Camino-Pontes

    (Biocruces Bizkaia Health Research Institute, 48903 Barakaldo, Spain
    Biomedical Research Doctorate Program, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain)

  • Ricardo Salinas Martínez

    (Department of Geriatrics, “José Eleuterio González” University Hospital, Autonomous University of Nuevo León, Monterrey 64460, Mexico)

  • Juan Carlos Arango-Lasprilla

    (Department of Psychology, Virginia Commonwealth University Richmond, Richmond, VA 23284, USA)

Abstract

To our knowledge, this is the first study reported in the literature that has validated the Norma Latina Battery in a population of people with Alzheimer’s disease (AD) in Mexico. The objective of the study was to determine the discriminant validity of the Norma Latina Battery in a group of Mexican individuals with AD and a group of heathy controls (HC). The Norma Latina Battery was administered to 234 Mexican participants (117 HC and 117 individuals with AD). Results show that: (1) the Norma Latina Battery has high discriminative capacity between groups in all domains; (2) participants with AD presented worse scores in each of the cognitive domains compared to the HC and a greater number of low scores in each of the established thresholds or cut-off points; and finally, (3) the Norma Latina Battery had optimal sensitivity and specificity, especially when a set was observed ≥5 scores below the 10th percentile or ≥4 scores below the 5th percentile. In conclusion, it is recommended that both clinicians and researchers use this battery in the evaluation of Mexican people with AD to better understand the prognosis of the disease and its subsequent treatment.

Suggested Citation

  • Silvia Núñez-Fernández & Diego Rivera & Eva María Arroyo-Anlló & Xóchitl Angélica Ortiz Jiménez & Borja Camino-Pontes & Ricardo Salinas Martínez & Juan Carlos Arango-Lasprilla, 2022. "Validation of the Norma Latina Neuropsychological Assessment Battery in Patients with Alzheimer’s Disease in Mexico," IJERPH, MDPI, vol. 19(18), pages 1-15, September.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:18:p:11322-:d:910442
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    References listed on IDEAS

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    1. Teresita Villaseñor-Cabrera & Joan Guàrdia-Olmos & Miriam Jiménez-Maldonado & Genoveva Rizo-Curiel & Maribel Peró-Cebollero, 2010. "Sensitivity and specificity of the Mini-Mental State Examination in the Mexican population," Quality & Quantity: International Journal of Methodology, Springer, vol. 44(6), pages 1105-1112, October.
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