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Effect of Obstructive Sleep Apnea on the Risk of Injuries—A Nationwide Population-Based Cohort Study

Author

Listed:
  • An-Che Cheng

    (Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei City 11490, Taiwan)

  • Gwo-Jang Wu

    (Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei City 11490, Taiwan
    Department of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei City 11490, Taiwan)

  • Chi-Hsiang Chung

    (School of Public Health, National Defense Medical Center, Taipei City 11490, Taiwan
    Department of Medical Research, Tri-Service General Hospital, Taipei City 11490, Taiwan
    Taiwanese Injury Prevention and Safety Promotion Association (TIPSPA), Taipei City 11490, Taiwan)

  • Kuo-Hsiang Wu

    (Department of Nursing, Tri-Service General Hospital, National Defense Medical Center, Taipei City 11490, Taiwan)

  • Chien-An Sun

    (Big Data Research Center, College of Medicine, Fu-Jen Catholic University, New Taipei City 24205, Taiwan
    Department of Public Health, College of Medicine, Fu-Jen Catholic University, New Taipei City 24205, Taiwan)

  • I-Duo Wang

    (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei City 11490, Taiwan)

  • Wu-Chien Chien

    (School of Public Health, National Defense Medical Center, Taipei City 11490, Taiwan
    Department of Medical Research, Tri-Service General Hospital, Taipei City 11490, Taiwan
    Taiwanese Injury Prevention and Safety Promotion Association (TIPSPA), Taipei City 11490, Taiwan
    Graduate Institute of Life Sciences, National Defense Medical Center, Taipei City 11490, Taiwan)

Abstract

Obstructive sleep apnea (OSA) has been reported to increase the risk of motor vehicle accidents. However, only few studies have investigated the effects of OSA on overall risk injury. The aim of study is to investigate whether OSA increases the risk of overall injury. The data were collected during 2000–2015 from Taiwan’s National Health Insurance Research Database. A total of 8901 individuals diagnosed with OSA were inpatients, or outpatients at least three times were enrolled. Finally, 6915 participants with OSA were included as the study cohort. We matched the study cohort with a comparison cohort, at a ratio of 1:4. Cox proportional hazards regression was used to analyse the association between OSA and overall injury. Patients with OSA had 83.1% increased risk of overall injury, compared to non-OSA individuals [adjusted hazards ratio (HR) = 1.831, confidence interval (CI) = 1.674–2.020, p < 0.001]. In the stratified age group, patients aged ≧65 years had the highest risk of injury (adjusted HR= 2.014; CI = 1.842–2.222, p < 0.001). Patients with OSA were at a higher risk of falls, traffic injury, poisoning, suffocation, suicide, and abuse or homicide than non-OSA individuals, with falls and traffic injury as the leading causes of injuries. The data demonstrated that patients with OSA have a higher risk of overall injury. The study results can be a reference for developing injury prevention strategies in the future. The general population and clinicians should have more awareness regarding OSA and its negative effects on injury development.

Suggested Citation

  • An-Che Cheng & Gwo-Jang Wu & Chi-Hsiang Chung & Kuo-Hsiang Wu & Chien-An Sun & I-Duo Wang & Wu-Chien Chien, 2021. "Effect of Obstructive Sleep Apnea on the Risk of Injuries—A Nationwide Population-Based Cohort Study," IJERPH, MDPI, vol. 18(24), pages 1-13, December.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:24:p:13416-:d:706909
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    References listed on IDEAS

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    1. Beatrice Ragnoli & Patrizia Pochetti & Alberto Raie & Mario Malerba, 2021. "Comorbid Insomnia and Obstructive Sleep Apnea (COMISA): Current Concepts of Patient Management," IJERPH, MDPI, vol. 18(17), pages 1-15, September.
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