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The Association between Influenza Vaccination and the Risk of SARS-CoV-2 Infection, Severe Illness, and Death: A Systematic Review of the Literature

Author

Listed:
  • Marco Del Riccio

    (Postgraduate Medical School in Public Health, University of Florence, 50134 Florence, Italy)

  • Chiara Lorini

    (Department of Health Sciences, University of Florence, 50134 Florence, Italy)

  • Guglielmo Bonaccorsi

    (Department of Health Sciences, University of Florence, 50134 Florence, Italy)

  • John Paget

    (Netherlands Institute for Health Services Research (Nivel), 3513 Utrecht, The Netherlands)

  • Saverio Caini

    (Molecular and Lifestyle Epidemiology Branch, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), 50139 Florence, Italy)

Abstract

We reviewed the association between seasonal influenza vaccination and the risk of SARS-CoV-2 infection or complicated illness or poor outcome (e.g., severe disease, need for hospitalization or ventilatory support, or death) among COVID-19 patients. None of the studies that were reviewed ( n = 12) found a significant increase in the risk of infection or in the illness severity or lethality, and some reported significantly inverse associations. Our findings support measures aimed at raising influenza vaccination coverage in the coming months.

Suggested Citation

  • Marco Del Riccio & Chiara Lorini & Guglielmo Bonaccorsi & John Paget & Saverio Caini, 2020. "The Association between Influenza Vaccination and the Risk of SARS-CoV-2 Infection, Severe Illness, and Death: A Systematic Review of the Literature," IJERPH, MDPI, vol. 17(21), pages 1-9, October.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:21:p:7870-:d:435492
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    Citations

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    Cited by:

    1. Armando Stefanati & Erica d’Anchera & Francesco De Motoli & Marta Savio & Maria Vittoria Toffoletto & Giovanni Gabutti, 2021. "Value of Immunizations during the COVID-19 Emergency," IJERPH, MDPI, vol. 18(2), pages 1-10, January.
    2. Jan E. Zejda & Grzegorz M. Brożek & Małgorzata Kowalska & Kamil Barański & Angelina Kaleta-Pilarska & Artur Nowakowski & Yuchen Xia & Paweł Buszman, 2021. "Seroprevalence of Anti-SARS-CoV-2 Antibodies in a Random Sample of Inhabitants of the Katowice Region, Poland," IJERPH, MDPI, vol. 18(6), pages 1-10, March.

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