IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v17y2020i12p4607-d376827.html
   My bibliography  Save this article

Implant Placement in Patients under Treatment with Rivaroxaban: A Retrospective Clinical Study

Author

Listed:
  • Guido Galletti

    (Department of Surgical, Medical, Molecular and of Critical Area Pathologies, Complex Operative Unit of Stomatology and Oral Surgery, University-Hospital of Pisa, University of Pisa, 56126 Pisa, Italy
    The two authors contributed equally to the realization of this study.)

  • Fortunato Alfonsi

    (Department of Surgical, Medical, Molecular and of Critical Area Pathologies, Complex Operative Unit of Stomatology and Oral Surgery, University-Hospital of Pisa, University of Pisa, 56126 Pisa, Italy
    The two authors contributed equally to the realization of this study.)

  • Angelo Raffaele

    (Complex Operative Unit of Geriatrics, SS Filippo e Nicola Hospital, 67051 Avezzano, Italy)

  • Nicola Alberto Valente

    (Unit of Oral Surgery and Implantology, Service of Maxillofacial and Buccal Surgery, Department of Surgery, Geneva University Hospitals, University of Geneva, 1205 Geneva, Switzerland
    Department of Stomatology, Faculty of Dentistry, University of Seville, 41009 Seville, Spain)

  • Sibylle Chatelain

    (Unit of Oral Surgery and Implantology, Service of Maxillofacial and Buccal Surgery, Department of Surgery, Geneva University Hospitals, University of Geneva, 1205 Geneva, Switzerland
    Department of Oral and Maxillofacial Surgery, Vaud University Hospital (CHUV Centre Hospitalier Universitaire Vaudois), 1011 Lausanne, Switzerland)

  • Roni Kolerman

    (Department of Periodontology and Dental Implantology, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv 6997801, Israel)

  • Chiara Cinquini

    (Department of Surgical, Medical, Molecular and of Critical Area Pathologies, Complex Operative Unit of Stomatology and Oral Surgery, University-Hospital of Pisa, University of Pisa, 56126 Pisa, Italy)

  • Stefano Romeggio

    (Private Practice, Innova Clinique, 28845 Domodossola, Italy)

  • Giovanna Iezzi

    (Department of Medical, Oral and Biotechnological Sciences, School of Dentistry, University of Chieti and Pescara, 66100 Chieti, Italy)

  • Antonio Barone

    (Department of Surgical, Medical, Molecular and of Critical Area Pathologies, Complex Operative Unit of Stomatology and Oral Surgery, University-Hospital of Pisa, University of Pisa, 56126 Pisa, Italy
    Unit of Oral Surgery and Implantology, Service of Maxillofacial and Buccal Surgery, Department of Surgery, Geneva University Hospitals, University of Geneva, 1205 Geneva, Switzerland)

Abstract

The management of patients under treatment with Direct Oral Anticoagulants (DOACs) has led clinicians to deal with two clinical issues, such as the hemorrhagic risk in case of non-interruption or the risk of thromboembolism in case of suspension of the treatment. The primary aim of this retrospective study was to evaluate the incidence of perioperative bleeding events and healing complications in patients who were under treatment with Rivaroxaban and who received dental implants and immediate prosthetic restoration. Patients treated with Rivaroxaban (Xarelto 20 mg daily) and who needed implant rehabilitation were selected. Four to six implants were placed in mandibular healed sites or fresh extraction sockets. All patients, in agreement with their physicians, interrupted the medication for 24 h and received implants and immediate restorations. Twelve patients and 57 implants were analyzed in the study. No major postoperative bleeding events were reported. Three patients (25%) presented slight immediate postoperative bleeding controlled with compression only. The implant and prosthetic survival rate were both 100% after 1 year. Within the limitations of this study, multiple implant placement with an immediate loading can be performed without any significant complication with a 24 h discontinuation of Rivaroxaban, in conjunction with the patient’s physician.

Suggested Citation

  • Guido Galletti & Fortunato Alfonsi & Angelo Raffaele & Nicola Alberto Valente & Sibylle Chatelain & Roni Kolerman & Chiara Cinquini & Stefano Romeggio & Giovanna Iezzi & Antonio Barone, 2020. "Implant Placement in Patients under Treatment with Rivaroxaban: A Retrospective Clinical Study," IJERPH, MDPI, vol. 17(12), pages 1-13, June.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:12:p:4607-:d:376827
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/17/12/4607/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/17/12/4607/
    Download Restriction: no
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Andrea Boccatonda & Alessio Frisone & Felice Lorusso & Calogero Bugea & Maristella Di Carmine & Cosima Schiavone & Giulio Cocco & Damiano D’Ardes & Antonio Scarano & Maria Teresa Guagnano, 2023. "Perioperative Management of Antithrombotic Therapy in Patients Who Undergo Dental Procedures: A Systematic Review of the Literature and Network Meta-Analysis," IJERPH, MDPI, vol. 20(7), pages 1-13, March.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:17:y:2020:i:12:p:4607-:d:376827. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.