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PM 2.5 and Cardiovascular Diseases in the Elderly: An Overview

Author

Listed:
  • Chenchen Wang

    (Department of Clinical Laboratory Medicine, School of Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China)

  • Yifan Tu

    (Department of Clinical Laboratory Medicine, School of Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China)

  • Zongliang Yu

    (Department of Cardiology, The First People's Hospital of Kunshan Affiliated to Jiangsu University, 91 Qianjin West Road, Kunshan 215132, China)

  • Rongzhu Lu

    (Department of Preventive Medicine and Public Health Laboratory Sciences, School of Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China
    Center of Experimental Research, The First People's Hospital of Kunshan Affiliated to Jiangsu University, 91 Qianjin West Road, Kunshan 215132, China)

Abstract

Background : Cardiovascular disease (CVD) is the leading cause of mortality and morbidity in the elderly and the ambient concentration of PM 2.5 has been associated with several cardiovascular diseases. Methods : We describe the present state of planetary air pollution, analyze epidemiological studies linking PM 2.5 and CVD, and discuss multiple pathophysiological mechanisms linking PM 2.5 and CVD. Results : A few epidemiological studies show that the elderly appear specifically susceptible to adverse cardiovascular effects triggered by PM 2.5 exposure. Plausible pathophysiological mechanisms include inflammatory dysfunction, oxidative stress, abnormal activation of the hemostatic system and disturbance of the autonomic nervous system. Conclusions : An in-depth knowledge of the chemical compounds, pathophysiological mechanisms, and epidemiological studies of PM 2.5 are recommended to understand this important and modifiable factor contributing to geriatric CVD burden. We offer public health recommendations to reduce this preventable cause of disease and death.

Suggested Citation

  • Chenchen Wang & Yifan Tu & Zongliang Yu & Rongzhu Lu, 2015. "PM 2.5 and Cardiovascular Diseases in the Elderly: An Overview," IJERPH, MDPI, vol. 12(7), pages 1-11, July.
    • Handle: RePEc:gam:jijerp:v:12:y:2015:i:7:p:8187-8197:d:52704
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    Citations

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    Cited by:

    1. Ching-Chang Cho & Wen-Yeh Hsieh & Chin-Hung Tsai & Cheng-Yi Chen & Hui-Fang Chang & Chih-Sheng Lin, 2018. "In Vitro and In Vivo Experimental Studies of PM 2.5 on Disease Progression," IJERPH, MDPI, vol. 15(7), pages 1-26, July.
    2. Pierre Masselot & Fateh Chebana & Éric Lavigne & Céline Campagna & Pierre Gosselin & Taha B.M.J. Ouarda, 2019. "Toward an Improved Air Pollution Warning System in Quebec," IJERPH, MDPI, vol. 16(12), pages 1-14, June.
    3. Yan Li & Hua Yu & Siqian Zheng & Yang Miao & Shi Yin & Peng Li & Ying Bian, 2016. "Direct Quantification of Rare Earth Elements Concentrations in Urine of Workers Manufacturing Cerium, Lanthanum Oxide Ultrafine and Nanoparticles by a Developed and Validated ICP-MS," IJERPH, MDPI, vol. 13(3), pages 1-10, March.
    4. Shaohong Mu & Weixiu Li & Muhammad Mohiuddin, 2022. "The Impact of Low-Carbon City (LCC) on Elderly People’s Health: Evidence from a Natural Experiment in China," IJERPH, MDPI, vol. 19(15), pages 1-18, August.
    5. Dan Xu & Wenpeng Lin & Jun Gao & Yue Jiang & Lubing Li & Fei Gao, 2022. "PM 2.5 Exposure and Health Risk Assessment Using Remote Sensing Data and GIS," IJERPH, MDPI, vol. 19(10), pages 1-24, May.
    6. Puwei Zhang & Li Wu & Rui Li, 2023. "Development Drivers of Rural Summer Health Tourism for the Urban Elderly: A Demand- and Supply-Based Framework," Sustainability, MDPI, vol. 15(13), pages 1-27, July.
    7. Karina Camasmie Abe & Simone Georges El Khouri Miraglia, 2016. "Health Impact Assessment of Air Pollution in São Paulo, Brazil," IJERPH, MDPI, vol. 13(7), pages 1-10, July.
    8. Raj P. Fadadu & John R. Balmes & Stephanie M. Holm, 2020. "Differences in the Estimation of Wildfire-Associated Air Pollution by Satellite Mapping of Smoke Plumes and Ground-Level Monitoring," IJERPH, MDPI, vol. 17(21), pages 1-9, November.

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