IDEAS home Printed from https://ideas.repec.org/a/eee/phsmap/v345y2005i1p173-184.html
   My bibliography  Save this article

Recoiling DNA molecule: simulation and experiment

Author

Listed:
  • Neto, José Coelho
  • Dickman, Ronald
  • Mesquita, O.N.

Abstract

Single molecule DNA experiments often generate data from force versus extension measurements involving the tethering of a microsphere to one end of a single DNA molecule while the other is attached to a substrate. We show that the persistence length of single DNA molecules can also be measured based on the recoil dynamics of these DNA-microsphere complexes if appropriate corrections are made to the friction coefficient of the microsphere in the vicinity of the substrate. Comparison between computer simulated recoil curves, generated from the corresponding Langevin equation, and experimental recoils are used to assure the validity of data analysis.

Suggested Citation

  • Neto, José Coelho & Dickman, Ronald & Mesquita, O.N., 2005. "Recoiling DNA molecule: simulation and experiment," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 345(1), pages 173-184.
    • Handle: RePEc:eee:phsmap:v:345:y:2005:i:1:p:173-184
    DOI: 10.1016/j.physa.2004.07.029
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0378437104009884
    Download Restriction: Full text for ScienceDirect subscribers only. Journal offers the option of making the article available online on Science direct for a fee of $3,000
    File URL: https://libkey.io/10.1016/j.physa.2004.07.029?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:phsmap:v:345:y:2005:i:1:p:173-184. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.journals.elsevier.com/physica-a-statistical-mechpplications/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.