IDEAS home Printed from https://ideas.repec.org/a/eee/chsofr/v153y2021ip2s096007792100802x.html
   My bibliography  Save this article

Modeling and complexity in dynamics of T-cells and cytokines in dengue fever based on antiviral treatment

Author

Listed:
  • Sharma, Naveen
  • Singh, Ram
  • Cattani, Carlo
  • Pathak, Rachana

Abstract

Dengue fever is one of the most common vector-borne diseases spreading in tropical and subtropical regions of the world. It is commonly known as break-bone fever which has illness caused by dengue virus Aedes aegypti and Aedes albopictus mosquitoes. This paper presents a mathematical model for the dynamics of T-cells and cytokines in dengue infection based on antiviral treatment. We have classified the cell population into susceptible cell, infected cells, virus particles, T-cells and cytokines. Cytokines- a group of proteins play a very crucial role in elimination of dengue infection. We have considered death of cytokines during virus encounter. In earlier studies, only natural death rate of cytokines is considered. The stability analysis of the equilibrium points is discussed. If the reproduction number (R0) is less than 1, the endemic equilibrium point is stable and virus infection die out from the system and if reproduction umber is greater than 1, the endemic equilibrium point is unstable and virus infection persist in the system We also derived various key parameters which are responsible for extinction of virus from body. Numerical simulation has also been carried out to assess the effects of various key parameters on population.

Suggested Citation

  • Sharma, Naveen & Singh, Ram & Cattani, Carlo & Pathak, Rachana, 2021. "Modeling and complexity in dynamics of T-cells and cytokines in dengue fever based on antiviral treatment," Chaos, Solitons & Fractals, Elsevier, vol. 153(P2).
    • Handle: RePEc:eee:chsofr:v:153:y:2021:i:p2:s096007792100802x
    DOI: 10.1016/j.chaos.2021.111448
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S096007792100802X
    Download Restriction: Full text for ScienceDirect subscribers only
    File URL: https://libkey.io/10.1016/j.chaos.2021.111448?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Jajarmi, Amin & Arshad, Sadia & Baleanu, Dumitru, 2019. "A new fractional modelling and control strategy for the outbreak of dengue fever," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 535(C).
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Abidemi, Afeez & Ackora-Prah, Joseph & Fatoyinbo, Hammed Olawale & Asamoah, Joshua Kiddy K., 2022. "Lyapunov stability analysis and optimization measures for a dengue disease transmission model," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 602(C).

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Fatima, Bibi & Zaman, Gul, 2020. "Co-infection of Middle Eastern respiratory syndrome coronavirus and pulmonary tuberculosis," Chaos, Solitons & Fractals, Elsevier, vol. 140(C).
    2. Chimmula, Vinay Kumar Reddy & Zhang, Lei, 2020. "Time series forecasting of COVID-19 transmission in Canada using LSTM networks," Chaos, Solitons & Fractals, Elsevier, vol. 135(C).
    3. Hussain, Ghulam & Khan, Amir & Zahri, Mostafa & Zaman, Gul, 2022. "Ergodic stationary distribution of stochastic epidemic model for HBV with double saturated incidence rates and vaccination," Chaos, Solitons & Fractals, Elsevier, vol. 160(C).
    4. Qureshi, Sania & Atangana, Abdon, 2020. "Fractal-fractional differentiation for the modeling and mathematical analysis of nonlinear diarrhea transmission dynamics under the use of real data," Chaos, Solitons & Fractals, Elsevier, vol. 136(C).
    5. Baleanu, Dumitru & Jajarmi, Amin & Mohammadi, Hakimeh & Rezapour, Shahram, 2020. "A new study on the mathematical modelling of human liver with Caputo–Fabrizio fractional derivative," Chaos, Solitons & Fractals, Elsevier, vol. 134(C).
    6. Abboubakar, Hamadjam & Kombou, Lausaire Kemayou & Koko, Adamou Dang & Fouda, Henri Paul Ekobena & Kumar, Anoop, 2021. "Projections and fractional dynamics of the typhoid fever: A case study of Mbandjock in the Centre Region of Cameroon," Chaos, Solitons & Fractals, Elsevier, vol. 150(C).
    7. Danane, Jaouad & Allali, Karam & Hammouch, Zakia, 2020. "Mathematical analysis of a fractional differential model of HBV infection with antibody immune response," Chaos, Solitons & Fractals, Elsevier, vol. 136(C).
    8. Naik, Parvaiz Ahmad & Zu, Jian & Owolabi, Kolade M., 2020. "Global dynamics of a fractional order model for the transmission of HIV epidemic with optimal control," Chaos, Solitons & Fractals, Elsevier, vol. 138(C).
    9. DAŞBAŞI, Bahatdin, 2020. "Stability analysis of the hiv model through incommensurate fractional-order nonlinear system," Chaos, Solitons & Fractals, Elsevier, vol. 137(C).
    10. Defterli, Ozlem, 2021. "Comparative analysis of fractional order dengue model with temperature effect via singular and non-singular operators," Chaos, Solitons & Fractals, Elsevier, vol. 144(C).
    11. Ahmad, Saeed & Rahman, Mati ur & Arfan, Muhammad, 2021. "On the analysis of semi-analytical solutions of Hepatitis B epidemic model under the Caputo-Fabrizio operator," Chaos, Solitons & Fractals, Elsevier, vol. 146(C).
    12. Saad, Khaled M. & Gómez-Aguilar, J.F. & Almadiy, Abdulrhman A., 2020. "A fractional numerical study on a chronic hepatitis C virus infection model with immune response," Chaos, Solitons & Fractals, Elsevier, vol. 139(C).
    13. Kachia, Krunal & Solís-Pérez, J.E. & Gómez-Aguilar, J.F., 2020. "Chaos in a three-cell population cancer model with variable-order fractional derivative with power, exponential and Mittag-Leffler memories," Chaos, Solitons & Fractals, Elsevier, vol. 140(C).
    14. Belmahi, Naziha & Shawagfeh, Nabil, 2021. "A new mathematical model for the glycolysis phenomenon involving Caputo fractional derivative: Well posedness, stability and bifurcation," Chaos, Solitons & Fractals, Elsevier, vol. 142(C).
    15. Mustapha, Umar Tasiu & Qureshi, Sania & Yusuf, Abdullahi & Hincal, Evren, 2020. "Fractional modeling for the spread of Hookworm infection under Caputo operator," Chaos, Solitons & Fractals, Elsevier, vol. 137(C).
    16. Akinlar, Mehmet Ali & Tchier, Fairouz & Inc, Mustafa, 2020. "Chaos control and solutions of fractional-order Malkus waterwheel model," Chaos, Solitons & Fractals, Elsevier, vol. 135(C).
    17. Gao, Wei & Veeresha, P. & Prakasha, D.G. & Baskonus, Haci Mehmet & Yel, Gulnur, 2020. "New approach for the model describing the deathly disease in pregnant women using Mittag-Leffler function," Chaos, Solitons & Fractals, Elsevier, vol. 134(C).
    18. Ahmed, Nauman & Raza, Ali & Rafiq, Muhammad & Ahmadian, Ali & Batool, Namra & Salahshour, Soheil, 2021. "Numerical and bifurcation analysis of SIQR model," Chaos, Solitons & Fractals, Elsevier, vol. 150(C).
    19. Veeresha, P. & Baskonus, Haci Mehmet & Prakasha, D.G. & Gao, Wei & Yel, Gulnur, 2020. "Regarding new numerical solution of fractional Schistosomiasis disease arising in biological phenomena," Chaos, Solitons & Fractals, Elsevier, vol. 133(C).
    20. Kucche, Kishor D. & Sutar, Sagar T., 2021. "Analysis of nonlinear fractional differential equations involving Atangana-Baleanu-Caputo derivative," Chaos, Solitons & Fractals, Elsevier, vol. 143(C).

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:chsofr:v:153:y:2021:i:p2:s096007792100802x. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Thayer, Thomas R. (email available below). General contact details of provider: https://www.journals.elsevier.com/chaos-solitons-and-fractals .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.