IDEAS home Printed from https://ideas.repec.org/a/caa/jnlvet/v51y2006i5id5545-vetmed.html
   My bibliography  Save this article

γδ-TCR+ CD2- lymphocytes are recruited into bovine mammary gland after stimulation

Author

Listed:
  • M. Faldyna

    (Veterinary Research Institute, Brno, Czech Republic)

  • L. Leva

    (Veterinary Research Institute, Brno, Czech Republic)

  • Z. Sladek

    (Veterinary Research Institute, Brno, Czech Republic
    Mendel University of Agriculture and Forestry, Brno, Czech Republic)

  • D. Rysanek

    (Veterinary Research Institute, Brno, Czech Republic)

  • M. Toman

    (Veterinary Research Institute, Brno, Czech Republic)

Abstract

γδ-T-Cell Receptor (TCR) lymphocytes were detected in mammary gland lavages collected from 10 clinically healthy virgin heifers before and after intramammary stimulation with synthetic muramyl dipeptide analogue. Using two-colour flow cytometry, CD2+ and CD2- subsets of γδ-TCR lymphocytes were analyzed. CD2+ γδ-TCR lymphocytes markedly prevailed over CD2- cells in intact mammary gland: 88.9 ± 4.9% of γδ-TCR lymphocytes were CD2+. After stimulation, neutrophils and γδ-TCR lymphocytes were recruited into the mammary gland. Among γδ-TCR lymphocytes, CD2- cells were mainly responsible for their expansion. After stimulation, 60.8 ± 13.4% of γδ-TCR lymphocytes were CD2+ (P < 0.01 when compared with mammary gland lavages before stimulation). It follows from the present study that the cells seem to be involved in the first phase of a response to an infection affecting mammary gland.

Suggested Citation

  • M. Faldyna & L. Leva & Z. Sladek & D. Rysanek & M. Toman, 2006. "γδ-TCR+ CD2- lymphocytes are recruited into bovine mammary gland after stimulation," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 51(5), pages 258-264.
    • Handle: RePEc:caa:jnlvet:v:51:y:2006:i:5:id:5545-vetmed
    DOI: 10.17221/5545-VETMED
    as

    Download full text from publisher

    File URL: http://vetmed.agriculturejournals.cz/doi/10.17221/5545-VETMED.html
    Download Restriction: free of charge
    File URL: http://vetmed.agriculturejournals.cz/doi/10.17221/5545-VETMED.pdf
    Download Restriction: free of charge
    File URL: https://libkey.io/10.17221/5545-VETMED?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    More about this item

    Keywords

    cattle; udder; mastitis;
    All these keywords.

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:caa:jnlvet:v:51:y:2006:i:5:id:5545-vetmed. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Ivo Andrle (email available below). General contact details of provider: https://www.cazv.cz/en/home/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.