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A frontier approach for the production of enteric soft capsules containing omega-3 fatty acids and probiotics

Author

Listed:
  • Hayoung Kim

    (Ildong Bioscience, Pyeongtaek-si, Gyeonggi-do, Republic of Korea)

  • Won Yeong Bang

    (Ildong Bioscience, Pyeongtaek-si, Gyeonggi-do, Republic of Korea)

  • Boyoung Choi

    (Ildong Bioscience, Pyeongtaek-si, Gyeonggi-do, Republic of Korea)

  • Han Bin Lee

    (Ildong Bioscience, Pyeongtaek-si, Gyeonggi-do, Republic of Korea)

  • Jungwoo Yang

    (Department of Microbiology, College of Medicine, Dongguk University, Gyeongju, Republic of Korea)

Abstract

The study investigated whether omega-3 fatty acids could promote bacterial growth, acid and bile tolerance, and cell adhesion onto Caco-2 cells to develop a multifunctional enteric soft capsule containing probiotics and omega-3 fatty acids. The probiotic strains used were Enterococcus faecium IDCC 2102 and Bacillus coagulans IDCC 1201. Supplementation with omega-3 fatty acids did not significantly affect the growth and viability of either strain at lower concentrations (i.e. 0.5-1.0 w/w %). In comparison, the adhesion ability to Caco-2 cells of both strains was significantly increased (up to 107.5%). Furthermore, Bacillus coagulans IDCC 1201 [1 × 1010 CFU (colony forming unit) per capsule] contained together with omega-3 fatty acids (600 mg per capsule) in the enteric soft capsules showed a stability of over 95% during 12 months of storage at room temperature, which was similar to that of unencapsulated lyophilised probiotics. Thus, these results indicate that multifunctional food supplements in the form of enteric soft capsules are feasible.

Suggested Citation

  • Hayoung Kim & Won Yeong Bang & Boyoung Choi & Han Bin Lee & Jungwoo Yang, 2024. "A frontier approach for the production of enteric soft capsules containing omega-3 fatty acids and probiotics," Czech Journal of Food Sciences, Czech Academy of Agricultural Sciences, vol. 42(2), pages 127-135.
    • Handle: RePEc:caa:jnlcjf:v:42:y:2024:i:2:id:181-2023-cjfs
    DOI: 10.17221/181/2023-CJFS
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