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Optimal block designs for experiments on networks

Author

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  • Vasiliki Koutra
  • Steven G. Gilmour
  • Ben M. Parker

Abstract

We propose a method for constructing optimal block designs for experiments on networks. The response model for a given network interference structure extends the linear network effects model to incorporate blocks. The optimality criteria are chosen to reflect the experimental objectives and an exchange algorithm is used to search across the design space for obtaining an efficient design when an exhaustive search is not possible. Our interest lies in estimating the direct comparisons among treatments, in the presence of nuisance network effects that stem from the underlying network interference structure governing the experimental units, or in the network effects themselves. Comparisons of optimal designs under different models, including the standard treatment models, are examined by comparing the variance and bias of treatment effect estimators. We also suggest a way of defining blocks, while taking into account the interrelations of groups of experimental units within a network, using spectral clustering techniques to achieve optimal modularity. We expect connected units within closed‐form communities to behave similarly to an external stimulus. We provide evidence that our approach can lead to efficiency gains over conventional designs such as randomised designs that ignore the network structure and we illustrate its usefulness for experiments on networks.

Suggested Citation

  • Vasiliki Koutra & Steven G. Gilmour & Ben M. Parker, 2021. "Optimal block designs for experiments on networks," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 70(3), pages 596-618, June.
  • Handle: RePEc:bla:jorssc:v:70:y:2021:i:3:p:596-618
    DOI: 10.1111/rssc.12473
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    References listed on IDEAS

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    1. Kunert, Joachim & Martin, R. J., 2000. "On the determination of optimal designs for an interference model," Technical Reports 2000,17, Technische Universität Dortmund, Sonderforschungsbereich 475: Komplexitätsreduktion in multivariaten Datenstrukturen.
    2. Ernst Wit & Agostino Nobile & Raya Khanin, 2005. "Near‐optimal designs for dual channel microarray studies," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 54(5), pages 817-830, November.
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    Cited by:

    1. Vasiliki Koutra & Steven G. Gilmour & Ben M. Parker & Andrew Mead, 2023. "Design of Agricultural Field Experiments Accounting for both Complex Blocking Structures and Network Effects," Journal of Agricultural, Biological and Environmental Statistics, Springer;The International Biometric Society;American Statistical Association, vol. 28(3), pages 526-548, September.

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