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Stress and its Vulnerability to Addiction

Author

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  • Ashim Kumar Basak
  • Tridip chatterjee

Abstract

Stress is a normal and unavoidable part of our life. Numerous studies have linked stress with the addiction to drugs of abuse. Researchers have revealed that there is overlap between the neurocircuits that respond to drugs and those that respond to stresses. Like illicit drugs, stress can increase the dopamine release in the nucleus accumbens, a component of brain reward circuit. The release of dopamine in the nucleus accumbens is considered to be one of the major substrates of the addictive properties of drugs. In this article an attempt has been made to understand the cellular mechanism by which stress triggers the addictive behaviours acting on the brain reward circuit.

Suggested Citation

  • Ashim Kumar Basak & Tridip chatterjee, 2017. "Stress and its Vulnerability to Addiction," Global Journal of Intellectual & Developmental Disabilities, Juniper Publishers Inc., vol. 3(5), pages 127-129, December.
    • Handle: RePEc:adp:jgjidd:v:3:y:2017:i:5:p:127-129
    DOI: 10.19080/GJIDD.2017.03.555623
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