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On Human Malaria Parasite-Host Relationship, Sterile Immune Response and Cancer

Author

Listed:
  • Filiberto Malagón
  • Jorge Gonzáles-Angúlo
  • Elba Carrasco
  • Norma Rivera

    (Department of Microbiology and Parasitology, National Autonomous University of Mexico, Mexico)

Abstract

Brief semblance on the story of research on malaria vaccine development through the time since the discovery of the malaria parasites to our days is presented, and emphasis on general results obtained is done. The emergence of a purified living sporozoite vaccine attenuated by radiation, and cryopreserved, that promise to control global morbidity and mortality of the malaria in endemic countries, providing sterile immunization against sporozoites of Plasmodium falciparum is commented. Experimental facts on sterile immune state and development of neoplasms when after immunization the antigenic stimulation continues repeatedly are presented. A warning suggestion is made on monitoring the possible augmented oncogenic susceptibility of vaccinated individuals versus the none vaccinated, to evaluate this potential effect of the vaccine.

Suggested Citation

  • Filiberto Malagón & Jorge Gonzáles-Angúlo & Elba Carrasco & Norma Rivera, 2018. "On Human Malaria Parasite-Host Relationship, Sterile Immune Response and Cancer," Cancer Therapy & Oncology International Journal, Juniper Publishers Inc., vol. 9(1), pages 5-7, January.
    • Handle: RePEc:adp:jctoij:v:9:y:2018:i:1:p:5-7
    DOI: 10.19080/CTOIJ.2018.09.555752
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