IDEAS home Printed from https://ideas.repec.org/a/adm/journl/v8y2019i5p139-147.html
   My bibliography  Save this article

Plasticity of Mesenchymal Stem Cells based on Immune Regulation Network

Author

Listed:
  • Tingting Ren

Abstract

The immunomodulatory function of mesenchymal stem cells has received increasing attention and is widely used in the treatment of clinical immune diseases. The various signal-stimulating molecules during the inflammatory response are essential for the ability of MSCs to exert immunomodulatory effects and determine the fate of immune regulation in MSCs - pro-inflammatory and anti-inflammatory. Such plasticity relies on a regulatory network between immune cells and MSCs that is formed by cytokines, chemokines, and some small molecules. To gain a deeper understanding of the specific mechanisms by which MSCs exert immunomodulatory effects, it is necessary to clarify the factors involved in regulation, the series of cellular signaling pathways triggered by these factors, and the potential links between them. This article is based on these immune regulation networks, combined with the latest research trends, to provide a theoretical basis for better clinical improvement of MSCs treatment.

Suggested Citation

  • Tingting Ren, 2019. "Plasticity of Mesenchymal Stem Cells based on Immune Regulation Network," International Journal of Sciences, Office ijSciences, vol. 8(05), pages 139-147, May.
    • Handle: RePEc:adm:journl:v:8:y:2019:i:5:p:139-147
    DOI: 10.18483/ijSci.2096
    as

    Download full text from publisher

    File URL: https://www.ijsciences.com/pub/article/2096
    Download Restriction: no
    File URL: https://www.ijsciences.com/pub/pdf/V82019052096.pdf
    Download Restriction: no
    File URL: https://libkey.io/10.18483/ijSci.2096?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:adm:journl:v:8:y:2019:i:5:p:139-147. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Staff ijSciences (email available below). General contact details of provider: .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.