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Effect of Curcumin on Gastric Emptying Induced by L-arginine in Mice

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  • Yan-ting Liu
  • Jing Yu
  • Hong-wei Wang
  • Xiao-ling Yu

Abstract

Objective To investigate the mechanism of curcumin administration on gastric emptying induced by L-arginine in mice. Methods Kunming male mice were divided into control group, curcumin group, L-arginine group and curcumin L-arginine combination group.There were nine mice in each group. The curcumin group and curcumin L-arginine combination group were treated with curcumin solution once a day for 15 days. From the 11th day onwards, the L-arginine group and the curcumin L-arginine combination group were given intragastric administration of L-arginine once a day for 5 days. The other groups were given solvent solution as control. The gastric emptying rate, NO content and nitric oxide synthase (NOS) activity in gastric tissue were measured after fasting for 24 hours. Results There was no significant difference between single curcumin group and the control group (P>0.05). But the gastric emptying rate in L-arginine group was significantly lower (P

Suggested Citation

  • Yan-ting Liu & Jing Yu & Hong-wei Wang & Xiao-ling Yu, 2018. "Effect of Curcumin on Gastric Emptying Induced by L-arginine in Mice," International Journal of Sciences, Office ijSciences, vol. 7(03), pages 91-93, March.
    • Handle: RePEc:adm:journl:v:7:y:2018:i:3:p:91-93
    DOI: 10.18483/ijSci.1612
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