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Analysis of Ivermectin as Potential Inhibitor of SARS-CoV-2 Using Resonant Recognition Model

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  • Irena Cosic
  • Drasko Cosic
  • Ivan Loncarevic

Abstract

With worldwide spread of COVID-19 disease caused by SARS-CoV-2 virus, everyone is trying to find effective cure. One of the quickest approaches is to test existing already approved and safe drugs for possibility of their activity against SARS-CoV-2 virus. One of such possible drugs is ivermectin, which is FDA approved broad spectrum anti parasitic agent. Recently it has been shown that ivermectin has broad range of in vitro antiviral activities and it has been shown that ivermectin is an inhibitor of SARS-CoV-2. We have previously used our recently developed extended Resonant Recognition Model (RRM) for small molecules and we have proposed hat drugs like hydroxychloroquine, chloroquine and remdesivir can interfere with SARS-CoV-2 viral infection. Here, we have used an extended RRM model for small molecules to analyze the possibility for ivermectin, an already FDA-approved drug, to interfere with SARS-CoV-2 viral activity, which could lead to an effective cure.

Suggested Citation

  • Irena Cosic & Drasko Cosic & Ivan Loncarevic, 2021. "Analysis of Ivermectin as Potential Inhibitor of SARS-CoV-2 Using Resonant Recognition Model," International Journal of Sciences, Office ijSciences, vol. 10(01), pages 1-6, January.
  • Handle: RePEc:adm:journl:v:10:y:2021:i:1:p:1-6
    DOI: 10.18483/ijSci.2433
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    References listed on IDEAS

    as
    1. Irena Cosic & Vasilis Paspaliaris & Drasko Cosic, 2019. "Biophysical Insights into Cystic Fibrosis Based on Electromagnetic Resonances in CFTR Proteins," International Journal of Sciences, Office ijSciences, vol. 8(09), pages 1-8, September.
    2. Irena Cosic & Drasko Cosic & Ivan Loncarevic, 2020. "New Concept of Small Molecules Interaction with Proteins – An Application to Potential COVID-19 Drugs," International Journal of Sciences, Office ijSciences, vol. 9(09), pages 16-25, September.
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    Cited by:

    1. Irena Cosic & Drasko Cosic & Ivan Loncarevic, 2021. "Possibility to Interfere with Coronavirus RNA Replication Analyzed by Resonant Recognition Model," International Journal of Sciences, Office ijSciences, vol. 10(06), pages 22-28, June.

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    1. Irena Cosic & Drasko Cosic & Ivan Loncarevic, 2020. "New Concept of Small Molecules Interaction with Proteins – An Application to Potential COVID-19 Drugs," International Journal of Sciences, Office ijSciences, vol. 9(09), pages 16-25, September.
    2. Irena Cosic & Drasko Cosic & Ivan Loncarevic, 2021. "Possibility to Interfere with Coronavirus RNA Replication Analyzed by Resonant Recognition Model," International Journal of Sciences, Office ijSciences, vol. 10(06), pages 22-28, June.
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    4. Irena Cosic & Drasko Cosic, 2020. "Roll of Temperature in Living Systems Analysed Using the Resonant Recognition Model," International Journal of Sciences, Office ijSciences, vol. 9(04), pages 40-44, April.

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