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A Novel Micro RNA Feedback Loop of High Mobility Group Protein A1a in Regulating Estrogen Receptor Alpha Alternative Splicing

Author

Listed:
  • Kenji Ohe
  • Yoshihiro Harada
  • Yuta Horita
  • Hiroyoshi Harada
  • Hiroki Terai
  • Masayoshi Mori
  • Yusuke Murata
  • Munechika Enjoji

    (Department of Pharmacotherapeutics, Faculty of Phamaceutical Sciences, Fukuoka University, Fukuoka city, Japan)

  • Kenji Ashida

    (Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Kurume city, Japan)

Abstract

The hERα gene is known for its major role in estrogen dependent growth of breast cancer. ERα positivity is a hallmark in treating these cancers. Though there are many isoforms reported for hERα, the splicing regulation...

Suggested Citation

  • Kenji Ohe & Yoshihiro Harada & Yuta Horita & Hiroyoshi Harada & Hiroki Terai & Masayoshi Mori & Yusuke Murata & Munechika Enjoji & Kenji Ashida, 2018. "A Novel Micro RNA Feedback Loop of High Mobility Group Protein A1a in Regulating Estrogen Receptor Alpha Alternative Splicing," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 11(1), pages 8327-8332, November.
    • Handle: RePEc:abf:journl:v:11:y:2018:i:1:p:8327-8332
    DOI: 10.26717/BJSTR.2018.10.002058
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    More about this item

    Keywords

    Biomedical Sciences; Biomedical Research; Technical Research; ERα Gene; Hmga1a; Non Coding Exon; Splicing Regulation; Microrna; Tamoxifen Resistance;
    All these keywords.

    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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