Content
January 2015, Volume 517, Issue 7533
- 142-143 Mineralogy: Painful extractions
by Andrew Bloodworth - 143-143 Books in brief
by Barbara Kiser - 144-144 Resources: Silt, dams and hydraulic heroes
by Philip Ball - 145-145 Pollution: Uncouple from economy boom
by Hong-Wei Xiao & A. S. Mujumdar & Liming Che - 145-145 Pollution: Clear blue skies over Beijing
by Zhaohui Gong - 145-145 Pollution: Build on success in China
by Yansui Liu & Yuheng Li & Cong Chen - 145-145 International Council for Science responds
by Gordon McBean - 145-145 Peer review as a business transaction
by Eleftherios P. Diamandis - 148-149 Carbon at the coastal interface
by Nicolas Gruber - 149-150 Enzymes surf the heat wave
by A. Joshua Wand - 150-151 Unburnable fossil-fuel reserves
by Michael Jakob & Jérôme Hilaire - 152-153 Resistance through repopulation
by Ian F. Tannock - 153-154 Spin memories in for the long haul
by John J. L. Morton & Klaus Mølmer - 155-156 The versatile and plastic liver
by Meritxell Huch - 156-157 A three-dimensional neural compass
by David C. Rowland & May-Britt Moser - 159-164 Three-dimensional head-direction coding in the bat brain
by Arseny Finkelstein & Dori Derdikman & Alon Rubin & Jakob N. Foerster & Liora Las & Nachum Ulanovsky - 165-169 Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism
by Fiona Cuskin & Elisabeth C. Lowe & Max J. Temple & Yanping Zhu & Elizabeth A. Cameron & Nicholas A. Pudlo & Nathan T. Porter & Karthik Urs & Andrew J. Thompson & Alan Cartmell & Artur Rogowski & Brian S. Hamilton & Rui Chen & Thomas J. Tolbert & Kathleen Piens & Debby Bracke & Wouter Vervecken & Zalihe Hakki & Gaetano Speciale & Jose L. Munōz-Munōz & Andrew Day & Maria J. Peña & Richard McLean & Michael D. Suits & Alisdair B. Boraston & Todd Atherly & Cherie J. Ziemer & Spencer J. Williams & Gideon J. Davies & D. Wade Abbott & Eric C. Martens & Harry J. Gilbert - 170-173 Glutathione activates virulence gene expression of an intracellular pathogen
by Michelle L. Reniere & Aaron T. Whiteley & Keri L. Hamilton & Sonya M. John & Peter Lauer & Richard G. Brennan & Daniel A. Portnoy - 174-176 The temperature and chronology of heavy-element synthesis in low-mass stars
by P. Neyskens & S. Van Eck & A. Jorissen & S. Goriely & L. Siess & B. Plez - 177-180 Optically addressable nuclear spins in a solid with a six-hour coherence time
by Manjin Zhong & Morgan P. Hedges & Rose L. Ahlefeldt & John G. Bartholomew & Sarah E. Beavan & Sven M. Wittig & Jevon J. Longdell & Matthew J. Sellars - 181-186 High-value alcohols and higher-oxidation-state compounds by catalytic Z-selective cross-metathesis
by Ming Joo Koh & R. Kashif M. Khan & Sebastian Torker & Miao Yu & Malte S. Mikus & Amir H. Hoveyda - 187-190 The geographical distribution of fossil fuels unused when limiting global warming to 2 °C
by Christophe McGlade & Paul Ekins - 191-195 Segmented lateral dyke growth in a rifting event at Bárðarbunga volcanic system, Iceland
by Freysteinn Sigmundsson & Andrew Hooper & Sigrún Hreinsdóttir & Kristín S. Vogfjörd & Benedikt G. Ófeigsson & Elías Rafn Heimisson & Stéphanie Dumont & Michelle Parks & Karsten Spaans & Gunnar B. Gudmundsson & Vincent Drouin & Thóra Árnadóttir & Kristín Jónsdóttir & Magnús T. Gudmundsson & Thórdís Högnadóttir & Hildur María Fridriksdóttir & Martin Hensch & Páll Einarsson & Eyjólfur Magnússon & Sergey Samsonov & Bryndís Brandsdóttir & Robert S. White & Thorbjörg Ágústsdóttir & Tim Greenfield & Robert G. Green & Ásta Rut Hjartardóttir & Rikke Pedersen & Richard A. Bennett & Halldór Geirsson & Peter C. La Femina & Helgi Björnsson & Finnur Pálsson & Erik Sturkell & Christopher J. Bean & Martin Möllhoff & Aoife K. Braiden & Eva P. S. Eibl - 196-199 Copulation in antiarch placoderms and the origin of gnathostome internal fertilization
by John A. Long & Elga Mark-Kurik & Zerina Johanson & Michael S. Y. Lee & Gavin C. Young & Zhu Min & Per E. Ahlberg & Michael Newman & Roger Jones & Jan den Blaauwen & Brian Choo & Kate Trinajstic - 200-204 Calcium transient prevalence across the dendritic arbour predicts place field properties
by Mark E. J. Sheffield & Daniel A. Dombeck - 205-208 Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile
by Charlie G. Buffie & Vanni Bucci & Richard R. Stein & Peter T. McKenney & Lilan Ling & Asia Gobourne & Daniel No & Hui Liu & Melissa Kinnebrew & Agnes Viale & Eric Littmann & Marcel R. M. van den Brink & Robert R. Jenq & Ying Taur & Chris Sander & Justin R. Cross & Nora C. Toussaint & Joao B. Xavier & Eric G. Pamer - 209-213 Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance
by Antonina V. Kurtova & Jing Xiao & Qianxing Mo & Senthil Pazhanisamy & Ross Krasnow & Seth P. Lerner & Fengju Chen & Terrence T. Roh & Erica Lay & Philip Levy Ho & Keith Syson Chan - 214-218 T–B-cell entanglement and ICOSL-driven feed-forward regulation of germinal centre reaction
by Dan Liu & Heping Xu & Changming Shih & Zurong Wan & Xiaopeng Ma & Weiwei Ma & Dan Luo & Hai Qi - 219-222 EFF-1-mediated regenerative axonal fusion requires components of the apoptotic pathway
by Brent Neumann & Sean Coakley & Rosina Giordano-Santini & Casey Linton & Eui Seung Lee & Akihisa Nakagawa & Ding Xue & Massimo A. Hilliard - 223-226 Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal
by Paul A. DaRosa & Zhizhi Wang & Xiaomo Jiang & Jonathan N. Pruneda & Feng Cong & Rachel E. Klevit & Wenqing Xu - 227-230 The heat released during catalytic turnover enhances the diffusion of an enzyme
by Clement Riedel & Ronen Gabizon & Christian A. M. Wilson & Kambiz Hamadani & Konstantinos Tsekouras & Susan Marqusee & Steve Pressé & Carlos Bustamante - 231-233 Outreach: Speak up for science
by Virginia Gewin - 236-236 The descent of man
by Christoph Weber
January 2015, Volume 517, Issue 7532
- 6-6 The rising pressure of global water shortages
by Jan Eliasson - 7-8 Nicaragua defies canal protests
by Lucas Laursen - 8-9 Planet hunters plot course for habitable worlds
by Alexandra Witze - 9-10 Ebola raises profile of blood-based therapy
by Declan Butler - 10-11 What to expect in 2015
by Elizabeth Gibney - 12-13 Science in 2015
by Mark Zastrow - 18-20 Listings: Science in culture 2015
by Daniel Cressey - 21-21 Green heating plan threatens air quality
by Gordon McFiggans - 21-21 Harmful soot spurs climate-policy action
by David G. Victor & V. Ramanathan & Durwood Zaelke - 21-21 Criteria for Nature Index questioned
by Robin Haunschild & Lutz Bornmann - 21-21 New law risks release of invasive species
by Philip E. Hulme - 22-22 Paul von Ragué Schleyer (1930–2014)
by Henry F. Schaefer - 24-25 Entry signals control development
by Jonathan D. Dinman - 25-26 Like cartilage, but simpler
by Anne Ladegaard Skov - 26-27 Photosynthetic complex in close-up
by Ilme Schlichting - 28-29 Diverted on the way to memory
by Gordon Y. C. Cheung & Michael Otto - 29-30 It takes three to find the exit
by Mathieu Bollen - 30-31 Ocean circulation and rapid climate change
by Ellen E. Martin - 33-38 RNA regulons in Hox 5′ UTRs confer ribosome specificity to gene regulation
by Shifeng Xue & Siqi Tian & Kotaro Fujii & Wipapat Kladwang & Rhiju Das & Maria Barna - 39-43 Architecture and conformational switch mechanism of the ryanodine receptor
by Rouslan G. Efremov & Alexander Leitner & Ruedi Aebersold & Stefan Raunser - 44-49 Structure of a mammalian ryanodine receptor
by Ran Zalk & Oliver B. Clarke & Amédée des Georges & Robert A. Grassucci & Steven Reiken & Filippo Mancia & Wayne A. Hendrickson & Joachim Frank & Andrew R. Marks - 50-55 Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution
by Zhen Yan & Xiao-chen Bai & Chuangye Yan & Jianping Wu & Zhangqiang Li & Tian Xie & Wei Peng & Chang-cheng Yin & Xueming Li & Sjors H. W. Scheres & Yigong Shi & Nieng Yan - 56-59 A higher-than-predicted measurement of iron opacity at solar interior temperatures
by J. E. Bailey & T. Nagayama & G. P. Loisel & G. A. Rochau & C. Blancard & J. Colgan & Ph. Cosse & G. Faussurier & C. J. Fontes & F. Gilleron & I. Golovkin & S. B. Hansen & C. A. Iglesias & D. P. Kilcrease & J. J. MacFarlane & R. C. Mancini & S. N. Nahar & C. Orban & J.-C. Pain & A. K. Pradhan & M. Sherrill & B. G. Wilson - 60-63 Higher-than-predicted saltation threshold wind speeds on Titan
by Devon M. Burr & Nathan T. Bridges & John R. Marshall & James K. Smith & Bruce R. White & Joshua P. Emery - 64-67 Observation of quantized conductance in neutral matter
by Sebastian Krinner & David Stadler & Dominik Husmann & Jean-Philippe Brantut & Tilman Esslinger - 68-72 An anisotropic hydrogel with electrostatic repulsion between cofacially aligned nanosheets
by Mingjie Liu & Yasuhiro Ishida & Yasuo Ebina & Takayoshi Sasaki & Takaaki Hikima & Masaki Takata & Takuzo Aida - 73-76 Strong and deep Atlantic meridional overturning circulation during the last glacial cycle
by E. Böhm & J. Lippold & M. Gutjahr & M. Frank & P. Blaser & B. Antz & J. Fohlmeister & N. Frank & M. B. Andersen & M. Deininger - 77-80 Origins of major archaeal clades correspond to gene acquisitions from bacteria
by Shijulal Nelson-Sathi & Filipa L. Sousa & Mayo Roettger & Nabor Lozada-Chávez & Thorsten Thiergart & Arnold Janssen & David Bryant & Giddy Landan & Peter Schönheit & Bettina Siebers & James O. McInerney & William F. Martin - 81-84 Identification of multipotent mammary stem cells by protein C receptor expression
by Daisong Wang & Cheguo Cai & Xiaobing Dong & Qing Cissy Yu & Xiao-Ou Zhang & Li Yang & Yi Arial Zeng - 85-88 Hepatitis A virus and the origins of picornaviruses
by Xiangxi Wang & Jingshan Ren & Qiang Gao & Zhongyu Hu & Yao Sun & Xuemei Li & David J. Rowlands & Weidong Yin & Junzhi Wang & David I. Stuart & Zihe Rao & Elizabeth E. Fry - 89-93 Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation
by Xianqin Zhang & Dusan Bogunovic & Béatrice Payelle-Brogard & Véronique Francois-Newton & Scott D. Speer & Chao Yuan & Stefano Volpi & Zhi Li & Ozden Sanal & Davood Mansouri & Ilhan Tezcan & Gillian I. Rice & Chunyuan Chen & Nahal Mansouri & Seyed Alireza Mahdaviani & Yuval Itan & Bertrand Boisson & Satoshi Okada & Lu Zeng & Xing Wang & Hui Jiang & Wenqiang Liu & Tiantian Han & Delin Liu & Tao Ma & Bo Wang & Mugen Liu & Jing-Yu Liu & Qing K. Wang & Dilek Yalnizoglu & Lilliana Radoshevich & Gilles Uzé & Philippe Gros & Flore Rozenberg & Shen-Ying Zhang & Emmanuelle Jouanguy & Jacinta Bustamante & Adolfo García-Sastre & Laurent Abel & Pierre Lebon & Luigi D. Notarangelo & Yanick J. Crow & Stéphanie Boisson-Dupuis & Jean-Laurent Casanova & Sandra Pellegrini - 94-98 A PP1–PP2A phosphatase relay controls mitotic progression
by Agnes Grallert & Elvan Boke & Anja Hagting & Ben Hodgson & Yvonne Connolly & John R. Griffiths & Duncan L. Smith & Jonathon Pines & Iain M. Hagan - 99-103 Native structure of photosystem II at 1.95 Å resolution viewed by femtosecond X-ray pulses
by Michihiro Suga & Fusamichi Akita & Kunio Hirata & Go Ueno & Hironori Murakami & Yoshiki Nakajima & Tetsuya Shimizu & Keitaro Yamashita & Masaki Yamamoto & Hideo Ago & Jian-Ren Shen - 104-107 Structure of an integral membrane sterol reductase from Methylomicrobium alcaliphilum
by Xiaochun Li & Rita Roberti & Günter Blobel - 109-110 Programming tools: Adventures with R
by Sylvia Tippmann - 111-113 Hopes for the year ahead
by Monya Baker - 116-116 Infraction
by John Gilbey
December 2014, Volume 516, Issue 7531
- 49-49 Nature Index 2014 China
by Nick Campbell & Michelle Grayson - 289-289 Challenge the abuse of science in setting policy
by Guillaume Chapron - 291-291 Study points to press releases as sources of hype
by Chris Woolston - 295-296 Inside the cultural struggle to stamp out Ebola
by Erika Check Hayden - 297-297 Flock of geneticists redraws bird family tree
by Ewen Callaway - 298-299 Putin’s Russia divides and enrages scientists
by Quirin Schiermeier - 300-303 365 days: 2014 in science
by Lauren Morello & Alison Abbott & Declan Butler & Ewen Callaway & David Cyranoski & Sara Reardon & Quirin Schiermeier & Alexandra Witze - 304-309 365 days: Images of the year
by Daniel Cressey - 321-323 Scientific method: Defend the integrity of physics
by George Ellis & Joe Silk - 323-325 Infectious disease: Mobilizing Ebola survivors to curb the epidemic
by Joshua M. Epstein & Lauren M. Sauer & Julia Chelen & Erez Hatna & Jon Parker & Richard E. Rothman & Lewis Rubinson - 326-328 In retrospect: Between Pacific Tides
by Aaron Hirsh - 329-329 What football can teach science
by Arturo Sala - 329-329 Prescient words on comets and life
by Milton Wainwright - 329-329 Flood resilience a must for delta cities
by Ruben Dahm - 329-329 Pool resources for protected areas
by Jon Hoekstra & Meg Symington & Chris Weaver - 329-329 Research agency will lose autonomy
by András Váradi & János Kertész - 330-330 Martin L. Perl (1927–2014)
by Valerie Halyo - 332-333 Better chemistry through radicals
by Steven L. Castle - 333-334 Toehold gene switches make big footprints
by Simon Ausländer & Martin Fussenegger - 334-335 How vector mosquitoes beat the heat
by Nora J. Besansky - 336-337 Mind the gaps
by Thomas M. Brooks - 337-338 Two steps for a magnetoelectric switch
by Kathrin Dörr & Andreas Herklotz - 338-339 An RNA-synthesizing machine
by Robert M. Krug - 343-348 Functionalized olefin cross-coupling to construct carbon–carbon bonds
by Julian C. Lo & Jinghan Gui & Yuki Yabe & Chung-Mao Pan & Phil S. Baran - 349-354 An AUTS2–Polycomb complex activates gene expression in the CNS
by Zhonghua Gao & Pedro Lee & James M. Stafford & Melanie von Schimmelmann & Anne Schaefer & Danny Reinberg - 355-360 Structure of influenza A polymerase bound to the viral RNA promoter
by Alexander Pflug & Delphine Guilligay & Stefan Reich & Stephen Cusack - 361-366 Structural insight into cap-snatching and RNA synthesis by influenza polymerase
by Stefan Reich & Delphine Guilligay & Alexander Pflug & Hélène Malet & Imre Berger & Thibaut Crépin & Darren Hart & Thomas Lunardi & Max Nanao & Rob W. H. Ruigrok & Stephen Cusack - 367-369 The exclusion of a significant range of ages in a massive star cluster
by Chengyuan Li & Richard de Grijs & Licai Deng - 370-373 Deterministic switching of ferromagnetism at room temperature using an electric field
by J. T. Heron & J. L. Bosse & Q. He & Y. Gao & M. Trassin & L. Ye & J. D. Clarkson & C. Wang & Jian Liu & S. Salahuddin & D. C. Ralph & D. G. Schlom & J. Íñiguez & B. D. Huey & R. Ramesh - 374-378 Reconstruction and control of a time-dependent two-electron wave packet
by Christian Ott & Andreas Kaldun & Luca Argenti & Philipp Raith & Kristina Meyer & Martin Laux & Yizhu Zhang & Alexander Blättermann & Steffen Hagstotz & Thomas Ding & Robert Heck & Javier Madroñero & Fernando Martín & Thomas Pfeifer - 379-382 The contribution of the Precambrian continental lithosphere to global H2 production
by Barbara Sherwood Lollar & T. C. Onstott & G. Lacrampe-Couloume & C. J. Ballentine - 383-386 Global protected area expansion is compromised by projected land-use and parochialism
by Federico Montesino Pouzols & Tuuli Toivonen & Enrico Di Minin & Aija S. Kukkala & Peter Kullberg & Johanna Kuusterä & Joona Lehtomäki & Henrikki Tenkanen & Peter H. Verburg & Atte Moilanen - 387-390 Signatures of aestivation and migration in Sahelian malaria mosquito populations
by A. Dao & A. S. Yaro & M. Diallo & S. Timbiné & D. L. Huestis & Y. Kassogué & A. I. Traoré & Z. L. Sanogo & D. Samaké & T. Lehmann - 391-394 A relative shift in cloacal location repositions external genitalia in amniote evolution
by Patrick Tschopp & Emma Sherratt & Thomas J. Sanger & Anna C. Groner & Ariel C. Aspiras & Jimmy K. Hu & Olivier Pourquié & Jérôme Gros & Clifford J. Tabin - 395-399 Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors
by Thorsten Gnad & Saskia Scheibler & Ivar von Kügelgen & Camilla Scheele & Ana Kilić & Anja Glöde & Linda S. Hoffmann & Laia Reverte-Salisa & Philipp Horn & Samet Mutlu & Ali El-Tayeb & Mathias Kranz & Winnie Deuther-Conrad & Peter Brust & Martin E. Lidell & Matthias J. Betz & Sven Enerbäck & Jürgen Schrader & Gennady G. Yegutkin & Christa E. Müller & Alexander Pfeifer - 400-404 Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
by Kyle W. McCracken & Emily M. Catá & Calyn M. Crawford & Katie L. Sinagoga & Michael Schumacher & Briana E. Rockich & Yu-Hwai Tsai & Christopher N. Mayhew & Jason R. Spence & Yana Zavros & James M. Wells - 405-409 Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells
by Jichang Wang & Gangcai Xie & Manvendra Singh & Avazeh T. Ghanbarian & Tamás Raskó & Attila Szvetnik & Huiqiang Cai & Daniel Besser & Alessandro Prigione & Nina V. Fuchs & Gerald G. Schumann & Wei Chen & Matthew C. Lorincz & Zoltán Ivics & Laurence D. Hurst & Zsuzsanna Izsvák - 410-413 Protein quality control at the inner nuclear membrane
by Anton Khmelinskii & Ewa Blaszczak & Marina Pantazopoulou & Bernd Fischer & Deike J. Omnus & Gaëlle Le Dez & Audrey Brossard & Alexander Gunnarsson & Joseph D. Barry & Matthias Meurer & Daniel Kirrmaier & Charles Boone & Wolfgang Huber & Gwenaël Rabut & Per O. Ljungdahl & Michael Knop - 414-417 Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection
by Mark W. Pellegrino & Amrita M. Nargund & Natalia V. Kirienko & Reba Gillis & Christopher J. Fiorese & Cole M. Haynes - 418-422 Rapid development of broadly influenza neutralizing antibodies through redundant mutations
by Leontios Pappas & Mathilde Foglierini & Luca Piccoli & Nicole L. Kallewaard & Filippo Turrini & Chiara Silacci & Blanca Fernandez-Rodriguez & Gloria Agatic & Isabella Giacchetto-Sasselli & Gabriele Pellicciotta & Federica Sallusto & Qing Zhu & Elisa Vicenzi & Davide Corti & Antonio Lanzavecchia - 423-427 In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system
by Danilo Maddalo & Eusebio Manchado & Carla P. Concepcion & Ciro Bonetti & Joana A. Vidigal & Yoon-Chi Han & Paul Ogrodowski & Alessandra Crippa & Natasha Rekhtman & Elisa de Stanchina & Scott W. Lowe & Andrea Ventura - 428-431 Rapid modelling of cooperating genetic events in cancer through somatic genome editing
by Francisco J. Sánchez-Rivera & Thales Papagiannakopoulos & Rodrigo Romero & Tuomas Tammela & Matthew R. Bauer & Arjun Bhutkar & Nikhil S. Joshi & Lakshmipriya Subbaraj & Roderick T. Bronson & Wen Xue & Tyler Jacks - 432-435 Cohesin-dependent globules and heterochromatin shape 3D genome architecture in S. pombe
by Takeshi Mizuguchi & Geoffrey Fudenberg & Sameet Mehta & Jon-Matthew Belton & Nitika Taneja & Hernan Diego Folco & Peter FitzGerald & Job Dekker & Leonid Mirny & Jemima Barrowman & Shiv I. S. Grewal - 436-439 R-loops induce repressive chromatin marks over mammalian gene terminators
by Konstantina Skourti-Stathaki & Kinga Kamieniarz-Gdula & Nicholas J. Proudfoot - 440-440 Correction: Corrigendum: Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles
by Susanne Walz & Francesca Lorenzin & Jennifer Morton & Katrin E. Wiese & Björn von Eyss & Steffi Herold & Lukas Rycak & Hélène Dumay-Odelot & Saadia Karim & Marek Bartkuhn & Frederik Roels & Torsten Wüstefeld & Matthias Fischer & Martin Teichmann & Lars Zender & Chia-Lin Wei & Owen Sansom & Elmar Wolf & Martin Eilers - 440-440 Editorial Expression of Concern: Non-adaptive origins of interactome complexity
by Ariel Fernández & Michael Lynch - 441-442 Nurture your online persona
by Peter Fiske - 444-444 The chains of plenty
by S. R. Algernon
December 2014, Volume 516, Issue 7530
- 1-2 Latest anomalocaridid affinities challenged
by Georg Mayer & Christine Martin & Ivo de Sena Oliveira & Franziska Anni Franke & Vladimir Gross - 3-4 Cong et al. reply
by Peiyun Cong & Xiaoya Ma & Xianguang Hou & Gregory D. Edgecombe & Nicholas J. Strausfeld - 145-145 Assess the real cost of research assessment
by Peter M. Atkinson - 147-147 Funders drawn to alternative metrics
by Chris Woolston - 151-152 Tsunami alerts fail to bridge the ‘last mile’
by Alexandra Witze - 153-153 Europe proposes joint Moon trips with Russia
by Elizabeth Gibney - 154-155 Ebola experts seek to expand testing
by Declan Butler - 156-156 Immune cells boost cancer survival from months to years
by Heidi Ledford - 157-157 Microsoft billionaire takes on cell biology
by Ewen Callaway - 158-161 Biodiversity: Life – a status report
by Richard Monastersky - 162-164 Stem cells: The black box of reprogramming
by David Cyranoski - 165-166 Microbiology: Ditch the term pathogen
by Arturo Casadevall & Liise-anne Pirofski - 168-169 In retrospect: Elective Affinities
by Matthew Bell - 169-169 Genetics: Genius on the fly
by Ewen Callaway - 170-170 Biodiversity reports need author rules
by Axel Hochkirch & Philip J. K. McGowan & Jeroen van der Sluijs - 170-170 Several fields still need primates
by Angela Roberts & Trevor Robbins - 170-170 Manage military land for the environment
by Rick Zentelis & David Lindenmayer - 170-170 Europe is failing young researchers
by Thomas Schäfer - 170-170 Engaged cohort good for science
by Katarzyna Kordas & Dara O'Hare & Makaela Jacobs-Pearson - 172-173 A designer's guide to pluripotency
by Jun Wu & Juan Carlos Izpisua Belmonte - 173-174 Breakthrough for protons
by Rohit N. Karnik - 175-176 A beacon for bacterial tubulin
by Elizabeth J. Harry - 176-178 Calcium-activated proteins visualized
by Matt Whorton - 178-179 The virtues of tiling
by Peter Fratzl - 179-180 When wells run dry
by Richard Taylor - 181-191 Catalytic enantioselective synthesis of quaternary carbon stereocentres
by Kyle W. Quasdorf & Larry E. Overman - 192-197 Divergent reprogramming routes lead to alternative stem-cell states
by Peter D. Tonge & Andrew J. Corso & Claudio Monetti & Samer M. I. Hussein & Mira C. Puri & Iacovos P. Michael & Mira Li & Dong-Sung Lee & Jessica C. Mar & Nicole Cloonan & David L. Wood & Maely E. Gauthier & Othmar Korn & Jennifer L. Clancy & Thomas Preiss & Sean M. Grimmond & Jong-Yeon Shin & Jeong-Sun Seo & Christine A. Wells & Ian M. Rogers & Andras Nagy - 198-206 Genome-wide characterization of the routes to pluripotency
by Samer M. I. Hussein & Mira C. Puri & Peter D. Tonge & Marco Benevento & Andrew J. Corso & Jennifer L. Clancy & Rowland Mosbergen & Mira Li & Dong-Sung Lee & Nicole Cloonan & David L. A. Wood & Javier Munoz & Robert Middleton & Othmar Korn & Hardip R. Patel & Carl A. White & Jong-Yeon Shin & Maely E. Gauthier & Kim-Anh Lê Cao & Jong-Il Kim & Jessica C. Mar & Nika Shakiba & William Ritchie & John E. J. Rasko & Sean M. Grimmond & Peter W. Zandstra & Christine A. Wells & Thomas Preiss & Jeong-Sun Seo & Albert J. R. Heck & Ian M. Rogers & Andras Nagy - 207-212 X-ray structure of a calcium-activated TMEM16 lipid scramblase
by Janine D. Brunner & Novandy K. Lim & Stephan Schenck & Alessia Duerst & Raimund Dutzler - 213-218 Structure and insights into the function of a Ca2+-activated Cl− channel
by Veronica Kane Dickson & Leanne Pedi & Stephen B. Long - 219-221 H2D+ observations give an age of at least one million years for a cloud core forming Sun-like stars
by Sandra Brünken & Olli Sipilä & Edward T. Chambers & Jorma Harju & Paola Caselli & Oskar Asvany & Cornelia E. Honingh & Tomasz Kamiński & Karl M. Menten & Jürgen Stutzki & Stephan Schlemmer - 222-226 Ultrasensitive mechanical crack-based sensor inspired by the spider sensory system
by Daeshik Kang & Peter V. Pikhitsa & Yong Whan Choi & Chanseok Lee & Sung Soo Shin & Linfeng Piao & Byeonghak Park & Kahp-Yang Suh & Tae-il Kim & Mansoo Choi - 227-230 Proton transport through one-atom-thick crystals
by S. Hu & M. Lozada-Hidalgo & F. C. Wang & A. Mishchenko & F. Schedin & R. R. Nair & E. W. Hill & D. W. Boukhvalov & M. I. Katsnelson & R. A. W. Dryfe & I. V. Grigorieva & H. A. Wu & A. K. Geim - 231-233 Formation and properties of ice XVI obtained by emptying a type sII clathrate hydrate
by Andrzej Falenty & Thomas C. Hansen & Werner F. Kuhs - 234-237 Isotopic constraints on marine and terrestrial N2O emissions during the last deglaciation
by Adrian Schilt & Edward J. Brook & Thomas K. Bauska & Daniel Baggenstos & Hubertus Fischer & Fortunat Joos & Vasilii V. Petrenko & Hinrich Schaefer & Jochen Schmitt & Jeffrey P. Severinghaus & Renato Spahni & Thomas F. Stocker - 238-241 Cell differentiation and germ–soma separation in Ediacaran animal embryo-like fossils
by Lei Chen & Shuhai Xiao & Ke Pang & Chuanming Zhou & Xunlai Yuan - 242-245 An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons
by Frank M. J. Jacobs & David Greenberg & Ngan Nguyen & Maximilian Haeussler & Adam D. Ewing & Sol Katzman & Benedict Paten & Sofie R. Salama & David Haussler - 246-249 Dietary modulation of the microbiome affects autoinflammatory disease
by John R. Lukens & Prajwal Gurung & Peter Vogel & Gordon R. Johnson & Robert A. Carter & Daniel J. McGoldrick & Srinivasa Rao Bandi & Christopher R. Calabrese & Lieselotte Vande Walle & Mohamed Lamkanfi & Thirumala-Devi Kanneganti - 250-253 Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG
by Parveen Goyal & Petya V. Krasteva & Nani Van Gerven & Francesca Gubellini & Imke Van den Broeck & Anastassia Troupiotis-Tsaïlaki & Wim Jonckheere & Gérard Péhau-Arnaudet & Jerome S. Pinkner & Matthew R. Chapman & Scott J. Hultgren & Stefan Howorka & Rémi Fronzes & Han Remaut - 254-258 Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma
by Jagan R. Muppidi & Roland Schmitz & Jesse A. Green & Wenming Xiao & Adrien B. Larsen & Sterling E. Braun & Jinping An & Ying Xu & Andreas Rosenwald & German Ott & Randy D. Gascoyne & Lisa M. Rimsza & Elias Campo & Elaine S. Jaffe & Jan Delabie & Erlend B. Smeland & Rita M. Braziel & Raymond R. Tubbs & J. R. Cook & Dennis D. Weisenburger & Wing C. Chan & Nagarajan Vaidehi & Louis M. Staudt & Jason G. Cyster - 259-262 MapZ marks the division sites and positions FtsZ rings in Streptococcus pneumoniae
by Aurore Fleurie & Christian Lesterlin & Sylvie Manuse & Chao Zhao & Caroline Cluzel & Jean-Pierre Lavergne & Mirita Franz-Wachtel & Boris Macek & Christophe Combet & Erkin Kuru & Michael S. VanNieuwenhze & Yves V. Brun & David Sherratt & Christophe Grangeasse - 263-266 Programmable RNA recognition and cleavage by CRISPR/Cas9
by Mitchell R. O’Connell & Benjamin L. Oakes & Samuel H. Sternberg & Alexandra East-Seletsky & Matias Kaplan & Jennifer A. Doudna - 267-271 Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation
by Harihar Basnet & Xue B. Su & Yuliang Tan & Jill Meisenhelder & Daria Merkurjev & Kenneth A. Ohgi & Tony Hunter & Lorraine Pillus & Michael G. Rosenfeld - 272-275 Regulation of RNA polymerase II activation by histone acetylation in single living cells
by Timothy J. Stasevich & Yoko Hayashi-Takanaka & Yuko Sato & Kazumitsu Maehara & Yasuyuki Ohkawa & Kumiko Sakata-Sogawa & Makio Tokunaga & Takahiro Nagase & Naohito Nozaki & James G. McNally & Hiroshi Kimura - 276-276 Correction: Corrigendum: Mitochondrial gene replacement in primate offspring and embryonic stem cells
by Masahito Tachibana & Michelle Sparman & Hathaitip Sritanaudomchai & Hong Ma & Lisa Clepper & Joy Woodward & Ying Li & Cathy Ramsey & Olena Kolotushkina & Shoukhrat Mitalipov - 276-276 Correction: Corrigendum: Producing primate embryonic stem cells by somatic cell nuclear transfer
by J. A. Byrne & D. A. Pedersen & L. L. Clepper & M. Nelson & W. G. Sanger & S. Gokhale & D. P. Wolf & S. M. Mitalipov - 276-276 Correction: Corrigendum: Nuclear reprogramming by interphase cytoplasm of two-cell mouse embryos
by Eunju Kang & Guangming Wu & Hong Ma & Ying Li & Rebecca Tippner-Hedges & Masahito Tachibana & Michelle Sparman & Don P. Wolf & Hans R. Schöler & Shoukhrat Mitalipov - 277-279 Ocean biology: Marine dreams
by Chris Woolston - 282-282 Missed message
by Rachel Reddick
December 2014, Volume 516, Issue 7529
- 1-1 Liver cancer
by Lauren Gravitz - 2-3 A preventable cancer
by Lucas Laursen - 4-6 Drug development: Try and try again
by Megan Scudellari - 7-7 Perspective: Time to face the fungal threat
by Felicia Wu - 8-9 Fatty liver disease: The liver labyrinth
by Branwen Morgan - 9-9 Science should keep out of partisan politics
by Daniel Sarewitz - 10-11 Sex differences: Luck of the chromosomes
by Courtney Humphries - 12-13 Vaccines: Taking a shot at protection
by Karen Weintraub - 14-16 Microbiome: The bacterial tightrope
by Katherine Bourzac - 15-16 Positive results spur race for Ebola vaccine
by Ewen Callaway - 16-17 Investigations launched into artificial tracheas
by David Cyranoski - 17-17 Perspective: Incision revision
by Myron Schwartz - 18-19 Rival species recast significance of ‘first bird’
by Ewen Callaway - 20-21 Climate tinkerers thrash out a plan
by Quirin Schiermeier - 21-22 Projects seek hidden effects of cancer drugs
by Heidi Ledford - 24-26 Physics: Quantum computer quest
by Elizabeth Gibney - 28-30 Natural gas: The fracking fallacy
by Mason Inman - 31-33 Climate change: Protect the world's deltas
by Liviu Giosan & James Syvitski & Stefan Constantinescu & John Day - 34-35 Mathematics: Set theory for six-year-olds
by Alex Bellos - 35-35 Books in brief
by Barbara Kiser - 36-36 Robotics: Bottom-up innovation
by Noel Sharkey - 37-37 Conservation: Focus on implementation
by Erik Meijaard & Douglas Sheil & Marcel Cardillo - 37-37 New pasture plants pose weed risk
by Don Driscoll & Jane Catford - 37-37 Conservation: More than inclusivity
by Laura J. Martin & Sara B. Pritchard - 37-37 Conservation: Stop profit trumping all
by Jessica Dempsey & Rosemary Collard & Juanita Sundberg - 37-37 Conservation: Listen to more voices
by David A. Wardle - 38-38 Herman Eisen (1918–2014)
by Lisa Steiner & Hidde Ploegh - 40-41 Autophagy transcribed
by Carmine Settembre & Andrea Ballabio - 41-42 Controls on isotopic gradients in rain
by Katherine H. Freeman - 42-43 A backup for bacteria
by Yao Wang & Julie K. Pfeiffer - 44-45 Stars fight back
by Philip F. Hopkins