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Classes empiétantes dans un graphe et application aux interactions entre protéines

Author

Listed:
  • Lucile Denoeud

    (ENST et CERMSEM)

  • Irène Charon

    (ENST)

  • Alain Guénoche

    (Institut de Mathématiques de Luminy)

  • Olivier Hudry

    (ENST et CERMSEM)

Abstract

In this paper, we study a method of classification by density in an unweighted graph. We search some areas with a high density of edges, that can be overlapping (we don't try to obtain a partition but some intrinsic classes). The method consists of two steps; first we determine the cores of the classes by means of a local density function and then we extend these cores by their neighbourhoods following a criterion on the density of the classes. Finally, the method is applied on a protein-protein interaction network, with the aim of predicting unknown cellular functions of some proteins

Suggested Citation

  • Lucile Denoeud & Irène Charon & Alain Guénoche & Olivier Hudry, 2005. "Classes empiétantes dans un graphe et application aux interactions entre protéines," Cahiers de la Maison des Sciences Economiques b05032, Université Panthéon-Sorbonne (Paris 1).
  • Handle: RePEc:mse:wpsorb:b05032
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    File URL: https://hal.archives-ouvertes.fr/hal-00199799
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    More about this item

    Keywords

    Bioinformatics; classification; density function; interaction network;
    All these keywords.

    JEL classification:

    • C69 - Mathematical and Quantitative Methods - - Mathematical Methods; Programming Models; Mathematical and Simulation Modeling - - - Other

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