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A Validation Study of Transgenerational Effects of Childhood Conditions on the Third Generation Offspring's Economic and Health Outcomes Potentially Driven by Epigenetic Imprinting

Author

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  • van den Berg, Gerard J.

    (University of Groningen)

  • Pinger, Pia

    (University of Cologne)

Abstract

At the crossroads of economics and human biology, this paper examines the extent to which pre-puberty nutritional conditions in one generation affect productivity-related outcomes in later generations. Recent studies have found a negative association between conditions at ages 8-12 and the grandchild's over-all and cardiovascular and diabetes mortality in a single historical dataset. It has been argued that this association reflects epigenetic imprinting, which has been corroborated in animal studies. We provide an external validation by analyzing the impact of the German famine of 1916-1918 on children and grandchildren of those exposed to the famine at ages 8-12. Our findings support and extend the evidence so far. Among the third generation, males (females) tend to have higher mental health scores if their paternal grandfather (maternal grandmother) was exposed. We do not find robust effects on the probability of obtaining an upper secondary education.

Suggested Citation

  • van den Berg, Gerard J. & Pinger, Pia, 2014. "A Validation Study of Transgenerational Effects of Childhood Conditions on the Third Generation Offspring's Economic and Health Outcomes Potentially Driven by Epigenetic Imprinting," IZA Discussion Papers 7999, Institute of Labor Economics (IZA).
    • Handle: RePEc:iza:izadps:dp7999
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    References listed on IDEAS

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    1. Gerard J. van den Berg & Pia R. Pinger & Johannes Schoch, 2016. "Instrumental Variable Estimation of the Causal Effect of Hunger Early in Life on Health Later in Life," Economic Journal, Royal Economic Society, vol. 126(591), pages 465-506, March.
    2. Tan, Chih Ming & Tan, Zhibo & Zhang, Xiaobo, 2014. "Sins of the fathers: The intergenerational legacy of the 1959-1961 Great Chinese Famine on children's cognitive development:," IFPRI discussion papers 1351, International Food Policy Research Institute (IFPRI).
    3. C. Justin Cook & Jason M. Fletcher & Angela Forgues, 2019. "Multigenerational Effects of Early-Life Health Shocks," Demography, Springer;Population Association of America (PAA), vol. 56(5), pages 1855-1874, October.
    4. Richter, André & Robling, Per Olof, 2013. "Multigenerational e ffects of the 1918-19 influenza pandemic in Sweden," Working Paper Series 5/2013, Stockholm University, Swedish Institute for Social Research.

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    More about this item

    Keywords

    famine; transgenerational transmission; epigenetics; mental health; education; long-run effects; nutrition; intergenerational effects; slow-growth period;
    All these keywords.

    JEL classification:

    • I12 - Health, Education, and Welfare - - Health - - - Health Behavior
    • J11 - Labor and Demographic Economics - - Demographic Economics - - - Demographic Trends, Macroeconomic Effects, and Forecasts

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