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Still in the shadow of the wall? The case of the Berlin biotechnology cluster

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  • Milad Abbasiharofteh
  • Tom Broekel

Abstract

The evolution of knowledge networks has recently received a lot of attention from researchers. Empirical studies have shown that different types of proximities and network structural properties play a decisive role in tie formation. The present paper contributes to this literature by arguing that while these are crucial, they do not capture the full range of localities’ influence on the evolution of knowledge networks. We support our argument with an empirical study on thedevelopment of the biotechnology knowledge network of Berlin from the early 1990s till 2016. The network was created by combining data on co-patenting, co-authorship and joint R&D projects. Forces driving the evolution of the network were identified with separable temporal exponential random graph models (STERGM). In addition to the ‘usual suspects’ (main proximity dimensions and structural factors), we found that the network is still developing in the ‘shadow of the wall’. The different social contexts in the different parts of the city of Berlin still hamper the establishment of collaborative ties between the former East and the former West Germany even 30 years after reunification.

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  • Milad Abbasiharofteh & Tom Broekel, 2020. "Still in the shadow of the wall? The case of the Berlin biotechnology cluster," Papers in Evolutionary Economic Geography (PEEG) 2030, Utrecht University, Department of Human Geography and Spatial Planning, Group Economic Geography, revised Aug 2020.
    • Handle: RePEc:egu:wpaper:2030
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    1. A J Scott, 1985. "Location Processes, Urbanization, and Territorial Development: An Exploratory Essay," Environment and Planning A, , vol. 17(4), pages 479-501, April.
    2. Max-Peter Menzel & Maryann P. Feldman & Tom Broekel, 2017. "Institutional change and network evolution: explorative and exploitative tie formations of co-inventors during the dot-com bubble in the Research Triangle region," Regional Studies, Taylor & Francis Journals, vol. 51(8), pages 1179-1191, August.
    3. Antonio Accetturo & Michele Cascarano & Petra Degasperi & Francesca Modena, 2019. "The effects of common culture and language on economic exchanges: evidence from tourist flows," Regional Studies, Taylor & Francis Journals, vol. 53(11), pages 1575-1590, November.
    4. Lucena-Piquero, D. & Vicente, Jérôme, 2019. "The visible hand of cluster policy makers: An analysis of Aerospace Valley (2006-2015) using a place-based network methodology," Research Policy, Elsevier, vol. 48(3), pages 830-842.
    5. Ron Boschma & Ron Martin (ed.), 2010. "The Handbook of Evolutionary Economic Geography," Books, Edward Elgar Publishing, number 12864.
    6. Corinne Autant-Bernard & Nadine Massard & Robin Cowan, 2014. "Editors’ introduction to spatial knowledge networks: structure, driving forces and innovative performances," The Annals of Regional Science, Springer;Western Regional Science Association, vol. 53(2), pages 315-323, September.
    7. Milad Abbasiharofteh, 2020. "Endogenous effects and cluster transition: a conceptual framework for cluster policy," European Planning Studies, Taylor & Francis Journals, vol. 28(12), pages 2508-2531, December.
    8. Thomas Farole & Andrés Rodríguez‐Pose & Michael Storper, 2011. "Cohesion Policy in the European Union: Growth, Geography, Institutions," Journal of Common Market Studies, Wiley Blackwell, vol. 49(5), pages 1089-1111, September.
    9. Scott L. Feld & Bernard Grofman, 1990. "Collectivities as Actors," Rationality and Society, , vol. 2(4), pages 429-448, October.
    10. Wickham, Hadley, 2007. "Reshaping Data with the reshape Package," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 21(i12).
    11. Domenico De Stefano & Susanna Zaccarin, 2013. "Modelling Multiple Interactions in Science and Technology Networks," Industry and Innovation, Taylor & Francis Journals, vol. 20(3), pages 221-240, April.
    12. Hagedoorn, John & Cloodt, Myriam, 2003. "Measuring innovative performance: is there an advantage in using multiple indicators?," Research Policy, Elsevier, vol. 32(8), pages 1365-1379, September.
    13. Pierre-Alexandre Balland & Mathijs De Vaan & Ron Boschma, 2013. "The dynamics of interfirm networks along the industry life cycle: The case of the global video game industry, 1987--2007," Journal of Economic Geography, Oxford University Press, vol. 13(5), pages 741-765, September.
    14. Ofuan. J. Ilaboya & Izien. F. Ohiokha, 2016. "Firm Age, Size and Profitability Dynamics: A Test of Learning by Doing and Structural Inertia Hypotheses," Business and Management Research, Business and Management Research, Sciedu Press, vol. 5(1), pages 29-39, March.
    15. Lionel Nesta & Pier-Paolo Saviotti, 2006. "Firm knowledge and market value in biotechnology," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 15(4), pages 625-652, August.
    16. Hunter, David R. & Handcock, Mark S. & Butts, Carter T. & Goodreau, Steven M. & Morris, Martina, 2008. "ergm: A Package to Fit, Simulate and Diagnose Exponential-Family Models for Networks," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 24(i03).
    17. Li, Guan-Cheng & Lai, Ronald & D’Amour, Alexander & Doolin, David M. & Sun, Ye & Torvik, Vetle I. & Yu, Amy Z. & Fleming, Lee, 2014. "Disambiguation and co-authorship networks of the U.S. patent inventor database (1975–2010)," Research Policy, Elsevier, vol. 43(6), pages 941-955.
    18. Nina Hjertvikrem & Rune Dahl Fitjar, 2021. "One or all channels for knowledge exchange in clusters? Collaboration, monitoring and recruitment networks in the subsea industry in Rogaland, Norway," Industry and Innovation, Taylor & Francis Journals, vol. 28(2), pages 182-200, February.
    19. Elisa Giuliani, 2007. "The selective nature of knowledge networks in clusters: evidence from the wine industry," Journal of Economic Geography, Oxford University Press, vol. 7(2), pages 139-168, March.
    20. Anne Nygaard Tanner, 2018. "Changing locus of innovation: a micro-process approach on the dynamics of proximity," European Planning Studies, Taylor & Francis Journals, vol. 26(12), pages 2304-2322, December.
    21. Wagner Joachim, 2016. "Still Different After All These Years Extensive and Intensive Margins of Exports in East and West German Manufacturing Enterprises," Journal of Economics and Statistics (Jahrbuecher fuer Nationaloekonomie und Statistik), De Gruyter, vol. 236(2), pages 297-322, March.
    22. Butts, Carter T., 2008. "network: A Package for Managing Relational Data in R," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 24(i02).
    23. Hunter, David R. & Goodreau, Steven M. & Handcock, Mark S., 2008. "Goodness of Fit of Social Network Models," Journal of the American Statistical Association, American Statistical Association, vol. 103, pages 248-258, March.
    24. Anne L. J. Ter Wal, 2014. "The dynamics of the inventor network in German biotechnology: geographic proximity versus triadic closure," Journal of Economic Geography, Oxford University Press, vol. 14(3), pages 589-620.
    25. Abbasiharofteh, Milad, 2020. "Endogenous effects and cluster transition: a conceptual framework for cluster policy," EconStor Open Access Articles and Book Chapters, ZBW - Leibniz Information Centre for Economics, vol. 28(12), pages 2508-2531.
    26. Michael Fritsch & Viktor Slavtchev, 2011. "Determinants of the Efficiency of Regional Innovation Systems," Regional Studies, Taylor & Francis Journals, vol. 45(7), pages 905-918.
    27. Elisa Giuliani, 2011. "Role of Technological Gatekeepers in the Growth of Industrial Clusters: Evidence from Chile," Regional Studies, Taylor & Francis Journals, vol. 45(10), pages 1329-1348, November.
    28. Lazzeretti, Luciana & Capone, Francesco, 2016. "How proximity matters in innovation networks dynamics along the cluster evolution. A study of the high technology applied to cultural goods," Journal of Business Research, Elsevier, vol. 69(12), pages 5855-5865.
    29. Michaela Trippl & Anne Otto, 2009. "How to Turn the Fate of Old Industrial Areas: A Comparison of Cluster-Based Renewal Processes in Styria and the Saarland," Environment and Planning A, , vol. 41(5), pages 1217-1233, May.
    30. Tom Broekel & Ron Boschma, 2012. "Knowledge networks in the Dutch aviation industry: the proximity paradox," Journal of Economic Geography, Oxford University Press, vol. 12(2), pages 409-433, March.
    31. Tom Broekel & Holger Graf, 2012. "Public research intensity and the structure of German R&D networks: a comparison of 10 technologies," Economics of Innovation and New Technology, Taylor & Francis Journals, vol. 21(4), pages 345-372, April.
    32. Tom Broekel & Matté Hartog, 2013. "Determinants of Cross-Regional R&D Collaboration Networks: An Application of Exponential Random Graph Models," Advances in Spatial Science, in: Thomas Scherngell (ed.), The Geography of Networks and R&D Collaborations, edition 127, chapter 0, pages 49-70, Springer.
    33. Maier, Philipp & Cavelaars, Paul, 2004. "Convergence of price levels: lessons from the German reunification," Journal of Comparative Economics, Elsevier, vol. 32(3), pages 467-481, September.
    34. Michael Fritsch & Holger Graf, 2010. "How General Conditions Affect Regional Innovation Systems - The Case of the Two Germanys," Jena Economics Research Papers 2010-054, Friedrich-Schiller-University Jena.
    35. Mark Lehrer, 2005. "Science-driven vs. market-pioneering high tech: comparative German technology sectors in the late nineteenth and late twentieth centuries," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 14(2), pages 251-278, April.
    36. Tom Broekel, 2012. "Collaboration Intensity and Regional Innovation Efficiency in Germany—A Conditional Efficiency Approach," Industry and Innovation, Taylor & Francis Journals, vol. 19(2), pages 155-179, February.
    37. Xavier Molina-Morales, F. & Belso-Martínez, José A. & Más-Verdú, Francisco & Martínez-Cháfer, Luis, 2015. "Formation and dissolution of inter-firm linkages in lengthy and stable networks in clusters," Journal of Business Research, Elsevier, vol. 68(7), pages 1557-1562.
    38. Breschi, Stefano & Catalini, Christian, 2010. "Tracing the links between science and technology: An exploratory analysis of scientists' and inventors' networks," Research Policy, Elsevier, vol. 39(1), pages 14-26, February.
    39. Christoph Roesler & Tom Broekel, 2017. "The role of universities in a network of subsidized R&D collaboration: The case of the biotechnology-industry in Germany," Review of Regional Research: Jahrbuch für Regionalwissenschaft, Springer;Gesellschaft für Regionalforschung (GfR), vol. 37(2), pages 135-160, October.
    40. André van Hoorn & Robbert Maseland, 2010. "Cultural Differences Between East and West Germany After 1991: Communist Values vs. Economic Performance?," Post-Print hal-00911822, HAL.
    41. José Antonio Belso-Martínez & Manuel Expósito-Langa & Francisco Mas-Verdú & F. Xavier Molina-Morales, 2017. "Dynamics of Brokerage Positions in Clusters: Evidence from the Spanish Foodstuffs Industry," Sustainability, MDPI, vol. 9(2), pages 1-18, February.
    42. Guido Buenstorf & Matthias Geissler & Stefan Krabel, 2016. "Locations of labor market entry by German university graduates: is (regional) beauty in the eye of the beholder?," Review of Regional Research: Jahrbuch für Regionalwissenschaft, Springer;Gesellschaft für Regionalforschung (GfR), vol. 36(1), pages 29-49, February.
    43. van Hoorn, André & Maseland, Robbert, 2010. "Cultural differences between East and West Germany after 1991: Communist values versus economic performance?," Journal of Economic Behavior & Organization, Elsevier, vol. 76(3), pages 791-804, December.
    44. Ron Boschma, 2005. "Proximity and Innovation: A Critical Assessment," Regional Studies, Taylor & Francis Journals, vol. 39(1), pages 61-74.
    45. Dohse, Dirk, 2000. "Technology policy and the regions -- the case of the BioRegio contest," Research Policy, Elsevier, vol. 29(9), pages 1111-1133, December.
    46. Tom Broekel & Matte Hartog, 2013. "Determinants of cross-regional R and D collaboration networks: an application of exponential random graph models," Working Papers on Innovation and Space 2013-04, Philipps University Marburg, Department of Geography.
    47. Francesco Capone & Luciana Lazzeretti, 2018. "The different roles of proximity in multiple informal network relationships: evidence from the cluster of high technology applied to cultural goods in Tuscany," Industry and Innovation, Taylor & Francis Journals, vol. 25(9), pages 897-917, October.
    48. Jun, Bogang & Yi, Seung-Kyu & Buchmann, Tobias & Mueller, Matthias, 2016. "The co-evolution of innovation networks: Collaboration between West and East Germany from 1972 to 2014," Hohenheim Discussion Papers in Business, Economics and Social Sciences 09-2016, University of Hohenheim, Faculty of Business, Economics and Social Sciences.
    49. Wickham, Hadley, 2011. "The Split-Apply-Combine Strategy for Data Analysis," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 40(i01).
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    3. Kabirigi, Michel, 2021. "Does the accessibility of a farmer predict the delivery of extension services? Evidence from Rwanda," EconStor Open Access Articles and Book Chapters, ZBW - Leibniz Information Centre for Economics, vol. 51(2), pages 187-196.
    4. Abbasiharofteh, Milad & Kogler, Dieter F. & Lengyel, Balázs, 2023. "Atypical combinations of technologies in regional co-inventor networks," Research Policy, Elsevier, vol. 52(10).
    5. Erlend Osland Simensen & Milad Abbasiharofteh, 2022. "Sectoral patterns of collaborative tie formation: investigating geographic, cognitive, and technological dimensions [Endogenous effects and cluster transition: a conceptual framework for cluster po," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 31(5), pages 1223-1258.
    6. Janssen, Matthijs J. & Abbasiharofteh, Milad, 2022. "Boundary spanning R&D collaboration: Key enabling technologies and missions as alleviators of proximity effects?," EconStor Open Access Articles and Book Chapters, ZBW - Leibniz Information Centre for Economics, vol. 180.
    7. Kabirigi, Michel & Abbasiharofteh, Milad & Sun, Zhanli & Hermans, Frans, 2022. "The importance of proximity dimensions in agricultural knowledge and innovation systems: The case of banana disease management in Rwanda," Agricultural Systems, Elsevier, vol. 202(C).
    8. Abbasiharofteh, Milad & Kinne, Jan & Krüger, Miriam, 2021. "The strength of weak and strong ties in bridging geographic and cognitive distances," ZEW Discussion Papers 21-049, ZEW - Leibniz Centre for European Economic Research.
    9. Lea F. Stöber & Marius Boesino & Andreas Pyka & Franziska Schuenemann, 2023. "Bioeconomy Innovation Networks in Urban Regions: The Case of Stuttgart," Land, MDPI, vol. 12(4), pages 1-22, April.
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    11. Janssen, Matthijs J. & Abbasiharofteh, Milad, 2022. "Boundary spanning R&D collaboration: Key enabling technologies and missions as alleviators of proximity effects?," Technological Forecasting and Social Change, Elsevier, vol. 180(C).

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    More about this item

    Keywords

    collaborative ties; knowledge network; network evolution; the Berlin biotech cluster;
    All these keywords.

    JEL classification:

    • N94 - Economic History - - Regional and Urban History - - - Europe: 1913-
    • O18 - Economic Development, Innovation, Technological Change, and Growth - - Economic Development - - - Urban, Rural, Regional, and Transportation Analysis; Housing; Infrastructure
    • R11 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General Regional Economics - - - Regional Economic Activity: Growth, Development, Environmental Issues, and Changes
    • L14 - Industrial Organization - - Market Structure, Firm Strategy, and Market Performance - - - Transactional Relationships; Contracts and Reputation

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