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Mapping of head and neck cancer patient concerns inventory scores on to Euroqol-Five Dimensions-Five Levels (EQ-5D-5L) health utility scores

Author

Listed:
  • Krishnakumar Thankappan

    (Amrita Institute of Medical Sciences and Research Center, Amrita Vishwa Vidyapeetham)

  • Tejal Patel

    (Amrita Institute of Medical Sciences and Research Center, Amrita Vishwa Vidyapeetham)

  • Krishna Kollamparambil Ajithkumar

    (Amrita Institute of Medical Sciences and Research Center, Amrita Vishwa Vidyapeetham)

  • Deepak Balasubramanian

    (Amrita Institute of Medical Sciences and Research Center, Amrita Vishwa Vidyapeetham)

  • Manu Raj

    (Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham)

  • Sujha Subramanian

    (RTI International)

  • Subramania Iyer

    (Amrita Institute of Medical Sciences and Research Center, Amrita Vishwa Vidyapeetham)

Abstract

Background The purpose of this paper is to map the number of concerns on the dimensions in Head and Neck Patient Concerns Inventory (PCI) on to the health utility (HU) index scores on Euroqol-Five Dimensions-Five levels {EQ-5D-5L) . Methods This is a cross-sectional survey conducted in patients who have completed their treatment. Four candidate models were considered, three based on ordinary least squares regression (OLS) and one two-parts model. Results A reduced OLS model based on ‘Physical and functional’, ‘Treatment-related’, and ‘Psychological, emotional and spiritual well-being’ domains was found best on the estimation sample. This was validated externally on a separate sample. Conclusions This is the first study that mapped a non-QOL tool to generate HU scores on EQ-5D-5L. The proposed mapping algorithm can estimate the cost–utility in economic evaluation studies when HU scores are not directly available. The algorithm will be best suited for studies in low-middle income countries.

Suggested Citation

  • Krishnakumar Thankappan & Tejal Patel & Krishna Kollamparambil Ajithkumar & Deepak Balasubramanian & Manu Raj & Sujha Subramanian & Subramania Iyer, 2022. "Mapping of head and neck cancer patient concerns inventory scores on to Euroqol-Five Dimensions-Five Levels (EQ-5D-5L) health utility scores," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 23(2), pages 225-235, March.
    • Handle: RePEc:spr:eujhec:v:23:y:2022:i:2:d:10.1007_s10198-021-01369-y
    DOI: 10.1007/s10198-021-01369-y
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    References listed on IDEAS

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    1. Stavros Petrou & Oliver Rivero-Arias & Helen Dakin & Louise Longworth & Mark Oppe & Robert Froud & Alastair Gray, 2015. "Preferred Reporting Items for Studies Mapping onto Preference-Based Outcome Measures: The MAPS Statement," Medical Decision Making, , vol. 35(6), pages 1-8, August.
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    3. Shankar Prinja & Laura E. Downey & Vijay K. Gauba & Soumya Swaminathan, 2018. "Health Technology Assessment for Policy Making in India: Current Scenario and Way Forward," PharmacoEconomics - Open, Springer, vol. 2(1), pages 1-3, March.
    4. Kelvin K. W. Chan & Andrew R. Willan & Michael Gupta & Eleanor Pullenayegum, 2014. "Underestimation of Uncertainties in Health Utilities Derived from Mapping Algorithms Involving Health-Related Quality-of-Life Measures," Medical Decision Making, , vol. 34(7), pages 863-872, October.
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    More about this item

    Keywords

    Cost–utility analysis; Health technology assessment; Patient Concerns Inventory; EQ-5D-5L; Mapping studies; Health Economics;
    All these keywords.

    JEL classification:

    • I1 - Health, Education, and Welfare - - Health
    • C1 - Mathematical and Quantitative Methods - - Econometric and Statistical Methods and Methodology: General

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