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Research landscape analysis for quality in Pharma 4.0 era

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  • Barenji, Reza Vatankhah
  • Hariry, Reza Ebrahimi
  • Demirkol, Denizhan
  • Daim, Tugrul U.

Abstract

This study focuses on the production phase of drug development and examines approaches and their progress indicators for enhancing the quality of pharmaceutical products and attaining consistency in Pharma 4.0. The research is conducted in three interconnected stages. In the first stage, a scientometric approach is incorporated into a detailed analysis of past studies, utilizing bibliometric analysis techniques. Following this, a narrative literature review is conducted based on the outcomes of the first stage to gain deeper insights into the selected technologies. Approaches for effective quality improvement include incorporating Quality by Design (QbD) for product and process development, utilizing Process Analytical Technology (PAT) in pharmaceutical processes, and adapting Real-Time Release Testing (RTRT) for quality control of raw materials, semi-products, and final products. While each of these approaches should be effectively implemented, integration with others is also necessary to maintain consistent quality. In the final stage of this paper, the authors make the first attempt to present a future-oriented integrated quality consistency system under the Pharma 4.0 philosophy, which encompasses effective production for quality improvement and consistency.

Suggested Citation

  • Barenji, Reza Vatankhah & Hariry, Reza Ebrahimi & Demirkol, Denizhan & Daim, Tugrul U., 2024. "Research landscape analysis for quality in Pharma 4.0 era," Technology in Society, Elsevier, vol. 76(C).
    • Handle: RePEc:eee:teinso:v:76:y:2024:i:c:s0160791x24000204
    DOI: 10.1016/j.techsoc.2024.102472
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    1. Donthu, Naveen & Kumar, Satish & Mukherjee, Debmalya & Pandey, Nitesh & Lim, Weng Marc, 2021. "How to conduct a bibliometric analysis: An overview and guidelines," Journal of Business Research, Elsevier, vol. 133(C), pages 285-296.
    2. Marina Dabić & Jane Maley & Leo-Paul Dana & Ivan Novak & Massimiliano M. Pellegrini & Andrea Caputo, 2020. "Pathways of SME internationalization: a bibliometric and systematic review," Small Business Economics, Springer, vol. 55(3), pages 705-725, October.
    3. Corbo, Leonardo & Kraus, Sascha & Vlačić, Božidar & Dabić, Marina & Caputo, Andrea & Pellegrini, Massimiliano M., 2023. "Coopetition and innovation: A review and research agenda," Technovation, Elsevier, vol. 122(C).
    4. Tekic, Zeljko & Füller, Johann, 2023. "Managing innovation in the era of AI," Technology in Society, Elsevier, vol. 73(C).
    5. Schinckus, Christophe, 2022. "A Nuanced perspective on blockchain technology and healthcare," Technology in Society, Elsevier, vol. 71(C).
    6. Losacker, Sebastian & Heiden, Stefanie & Liefner, Ingo & Lucas, Henning, 2023. "Rethinking bioeconomy innovation in sustainability transitions," Technology in Society, Elsevier, vol. 74(C).
    7. Coccia, Mario, 2023. "High potential of technology to face new respiratory viruses: mechanical ventilation devices for effective healthcare to next pandemic emergencies," Technology in Society, Elsevier, vol. 73(C).
    8. Regan, Tracy L., 2008. "Generic entry, price competition, and market segmentation in the prescription drug market," International Journal of Industrial Organization, Elsevier, vol. 26(4), pages 930-948, July.
    9. Huang, Jianan, 2021. "Trends of pharmaceutical corporations’ external innovation strategies: An inverse sigmoid curve," Technology in Society, Elsevier, vol. 67(C).
    10. Bate, Roger & Jin, Ginger Zhe & Mathur, Aparna, 2011. "Does price reveal poor-quality drugs? Evidence from 17 countries," Journal of Health Economics, Elsevier, vol. 30(6), pages 1150-1163.
    11. Miguel R. Lopes & Andrea Costigliola & Rui Pinto & Susana Vieira & Joao M.C. Sousa, 2020. "Pharmaceutical quality control laboratory digital twin – A novel governance model for resource planning and scheduling," International Journal of Production Research, Taylor & Francis Journals, vol. 58(21), pages 6553-6567, November.
    12. Earp, Brian D. & Savulescu, Julian, 2018. "Love drugs: Why scientists should study the effects of pharmaceuticals on human romantic relationships," Technology in Society, Elsevier, vol. 52(C), pages 10-16.
    13. Kristof Huysentruyt & Oeystein Kjoersvik & Pawel Dobracki & Elizabeth Savage & Ellen Mishalov & Mark Cherry & Eileen Leonard & Robert Taylor & Bhavin Patel & Danielle Abatemarco, 2021. "Validating Intelligent Automation Systems in Pharmacovigilance: Insights from Good Manufacturing Practices," Drug Safety, Springer, vol. 44(3), pages 261-272, March.
    14. Saha, Esha & Rathore, Pradeep & Parida, Ratri & Rana, Nripendra P., 2022. "The interplay of emerging technologies in pharmaceutical supply chain performance: An empirical investigation for the rise of Pharma 4.0," Technological Forecasting and Social Change, Elsevier, vol. 181(C).
    15. Reza Vatankhah Barenji, 2022. "A blockchain technology based trust system for cloud manufacturing," Journal of Intelligent Manufacturing, Springer, vol. 33(5), pages 1451-1465, June.
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