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Limpid and Pellucid- Clear Cell Renal Sarcoma

Author

Listed:
  • Anubha Bajaj

    (Consultant Histopathologist, A.B. Diagnostics, India)

Abstract

Initially scripted by Beckwith and Palmer, Morgan and Kidd and Marsden et al in 1978, clear cell renal sarcoma is an infrequently encountered neoplasm which expounds variable morphology and appears devoid of specific diagnostic markers. Genetic alterations within BCOR gene are implicated within tumorigenesis of clear cell renal carcinoma. Previously designated as ‘bone metastasizing renal tumour of childhood’, clear cell renal sarcoma is a frequently misinterpreted paediatric renal neoplasm. Tumour cells appear immune reactive to vimentin or Cyclin D1. Tumefaction is associated with significant predilection for bone metastasis. Clear cell renal sarcoma is constituted of miniature, uniform, plump, spherical cells delineating a ‘clear’ countenance which are pervaded with regular, fine nuclear chromatin.

Suggested Citation

  • Anubha Bajaj, 2023. "Limpid and Pellucid- Clear Cell Renal Sarcoma," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 54(1), pages 45377-45380, December.
    • Handle: RePEc:abf:journl:v:54:y:2023:i:1:p:45377-45380
    DOI: 10.26717/BJSTR.2023.54.008488
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