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Role of Iron Metabolism in Breast Cancer Patients

Author

Listed:
  • Rakesh Dhankhar

    (Professor, Department of Radiotherapy, Pt. B.D.S. PGIMS, Rohtak, Haryana, India.)

  • Adarsh C

    (Ex-Resident, Department of Radiotherapy, Pt. B.D.S. PGIMS, Rohtak, Haryana, India.)

  • Kiran Dahiya

    (Professor, Department of Biochemistry, Pt. B.D.S. PGIMS, Rohtak, Haryana, India.)

  • Veena Singh Ghalaut

    (Senior Professor and Head, Department of Biochemistry, Pt. B.D.S. PGIMS, Rohtak, Haryana, India.)

  • Nityasha

    (Professor, Department of Surgery, Pt. B.D.S. PGIMS, Rohtak, Haryana, India.)

  • Anil Kumar Dhull

    (Medical Officer, Department of Radiotherapy, Pt. B.D.S. PGIMS, Rohtak, Haryana, India.)

  • Anil Khurana

    (Medical Officer, Department of Radiotherapy, Pt. B.D.S. PGIMS, Rohtak, Haryana, India.)

Abstract

Iron metabolism is closely related to carcinogenesis. In this study, iron, ferritin and TIBC were analysed in 30 patients of early stage, 30 of advanced stage breast carcinoma before and after treatment and the results were compared with 30 healthy controls. The levels of all the three parameters were found to be significantly higher in breast cancer patients as compared to healthy controls and patients with advanced disease showed greater values as compared to early stage disease. These levels decreased after treatment and the difference was more significant in patients with complete response. Serum analyses of iron, ferritin and TIBC may help in assessing the severity and prognosis of the disease.

Suggested Citation

  • Rakesh Dhankhar & Adarsh C & Kiran Dahiya & Veena Singh Ghalaut & Nityasha & Anil Kumar Dhull & Anil Khurana, 2014. "Role of Iron Metabolism in Breast Cancer Patients," Cancers Review, Conscientia Beam, vol. 1(2), pages 45-51.
  • Handle: RePEc:pkp:canrev:2014:p:45-51
    DOI: 10.18488/journal.95/2014.1.2/95.2.45.51
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