IDEAS home Printed from
MyIDEAS: Log in (now much improved!) to save this article

Antimicrobial Effects of Garcinia Kola (Bitter Kola) on Some Selected Pathogens from University of Ilorin Teaching Hospital Ilorin, Nigeria

Listed author(s):

    (Department of Microbiology, University of Ilorin, Ilorin, Kwara state, Nigeria)

  • ALIYU Muhammed Babandoko

    (Department of Science Laboratory Technology Federal Polytechnic, Bida, Niger State, Nigeria)

  • KAYODE Rowland Monday Ojo

    (Department of Home economics and Food Science, University of Ilorin, Ilorin, Nigeria)

  • AJIBOYE Adeyinka Elizabeth

    (Department of Biosciences & Biotechnology,Kwara State University, Malete Via Ilorin, Nigeria)

  • AJIJOLAKEWU Abiodun Kamoldeen

    (Department of Microbiology, University of Ilorin, Ilorin, Kwara state, Nigeria)

Registered author(s):

    The antibacterial and antifungal activity of Garcinia kola of small and large seeds varieties were extracted in ethanol and water (cold and hot) and tested against some selected clinical bacterial and fungal isolates; Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Bacillus subtilis and Pseudomonas aeruginosa at concentrations of 10, 20, and 30 mg/ml. The same concentrations were used against the fungi Candida albicans and Aspergillus niger. Agar well diffusion method was employed to determine the antimicrobial activity of the extracts against test microorganisms. The results showed that the small seed ethanol and aqueous (hot water) extracts exhibited more antimicrobial activity at a concentration of 30 mg/ml, with zones of inhibition ranging from 17 to 23mm for ethanol. The aqueous (hot water) extracts showed zones of inhibition ranging from 20 to 27mm. The extracts also showed antifungal activity against Aspergillus niger. The minimum inhibitory concentration (MIC) showed antimicrobial activity at lowest concentration of 0.008mg/ml and maximum concentration of 5.0mg/ml against Staphylococcus aureus. There were presence of phytochemical compounds such as flavonoids, tannins, saponins, steroids, cardiac glycosides, and reducing sugars. The results imply that the ethanol and aqueous extracts of Garcinia kola seed posses strong antibacterial and antifungal properties when compared with standard antibiotics amoxicillin; ciproxin; tetracycline and streptomycin used during the investigation, and hence its potential as a useful chemotherapeutic agent in the treatment of bacterial and fungal infections in humans.

    If you experience problems downloading a file, check if you have the proper application to view it first. In case of further problems read the IDEAS help page. Note that these files are not on the IDEAS site. Please be patient as the files may be large.

    File URL:
    Download Restriction: no

    File URL:
    Download Restriction: no

    Article provided by Asian Economic and Social Society in its journal Journal of Asian Scientific Research.

    Volume (Year): 2 (2012)
    Issue (Month): 4 (April)
    Pages: 159-169

    in new window

    Handle: RePEc:asi:joasrj:2012:p:159-169
    Contact details of provider: Postal:
    Sadeeq Block, Near Fawara Chowk, Abbasia Town, Rahim Yar Khan - 64200, Punjab, Pakistan

    Web page:

    No references listed on IDEAS
    You can help add them by filling out this form.

    This item is not listed on Wikipedia, on a reading list or among the top items on IDEAS.

    When requesting a correction, please mention this item's handle: RePEc:asi:joasrj:2012:p:159-169. See general information about how to correct material in RePEc.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Qazi Muhammad Imran)

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If references are entirely missing, you can add them using this form.

    If the full references list an item that is present in RePEc, but the system did not link to it, you can help with this form.

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your profile, as there may be some citations waiting for confirmation.

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    This information is provided to you by IDEAS at the Research Division of the Federal Reserve Bank of St. Louis using RePEc data.