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Oleuropein as a novel anti-diabetic nutraceutical. An overview

Author

Listed:
  • Giuseppe Annunziata
  • Maria Maisto
  • Connie Schisano
  • Roberto Ciampaglia
  • Viviana Narciso
  • Gian Carlo Tenore
  • Ettore Novellino

    (Department of Pharmacy, University of Naples Federico II, Naples, Italy)

  • Luigi Barrea

    (Department of Clinical Medicine and Surgery, Federico II University Medical School of Naples, Italy)

Abstract

Among the cardiometabolic diseases, type 2 diabetes mellitus (T2DM) is one of the most diffused worldwide. Pharmacological treatments commonly used present several side effects, and this is driving people to search natural approaches. Olea europaea is currently investigated for its anti-diabetic potential. In particular, oleuropein (OLE), its main bioactive compound, have been demonstrated to exert interesting activities in management of T2DM, including hypoglycemic and antioxidant activities. The purpose of this manuscript is to review the available scientific evidence evaluating the role of OLE in managing T2DM.

Suggested Citation

  • Giuseppe Annunziata & Maria Maisto & Connie Schisano & Roberto Ciampaglia & Viviana Narciso & Gian Carlo Tenore & Ettore Novellino & Luigi Barrea, 2018. "Oleuropein as a novel anti-diabetic nutraceutical. An overview," Archives Of Diabetes & Obesity, Lupine Publishers, LLC, vol. 1(3), pages 54-58, August.
  • Handle: RePEc:abr:oajado:v:1:y:2018:i:3:p:54-58
    DOI: 10.32474/ADO.2018.01.000113
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    References listed on IDEAS

    as
    1. Giuseppe Annunziata & Gian Carlo Tenore & Ettore Novellino, 2018. "Resveratrol-based Nutraceuticals for the Management of Diabetes and Obesity: Real Therapeutic Potential or a mere Palliative?," Archives Of Diabetes & Obesity, Lupine Publishers, LLC, vol. 1(2), pages 34-35, June.
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