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Targeting the Immune Checkpoint in Cancer: Is This a Viable Treatment Option for AML?


  • Steven J Coles

    (Biomedical Research Group, University of Worcester, UK)


The immune suppressive mechanisms displayed by malignant cells are considered a central process in the pathogenesis of cancer. Research in this area has gained significant momentu mover the past 20 years, with several immune checkpoints identified, including; CTLA-4, CD200/CD200R, Tim-3/Galectin-9 and PD-L1/PD-1 (Figure 1).

Suggested Citation

  • Steven J Coles, 2018. "Targeting the Immune Checkpoint in Cancer: Is This a Viable Treatment Option for AML?," Open Access Journal of Oncology and Medicine, Lupine Publishers, LLC, vol. 1(2), pages 26-27, February.
  • Handle: RePEc:abr:joajom:v:1:y:2018:i:2:p:26-27
    DOI: 10.32474/OAJOM.2018.01.000107

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