Content
August 2018, Volume 560, Issue 7719
- 489-493 Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition
by Marcus Fulde & Felix Sommer & Benoit Chassaing & Kira Vorst & Aline Dupont & Michael Hensel & Marijana Basic & Robert Klopfleisch & Philip Rosenstiel & André Bleich & Fredrik Bäckhed & Andrew T. Gewirtz & Mathias W. Hornef - 494-498 RNA velocity of single cells
by Gioele La Manno & Ruslan Soldatov & Amit Zeisel & Emelie Braun & Hannah Hochgerner & Viktor Petukhov & Katja Lidschreiber & Maria E. Kastriti & Peter Lönnerberg & Alessandro Furlan & Jean Fan & Lars E. Borm & Zehua Liu & David Bruggen & Jimin Guo & Xiaoling He & Roger Barker & Erik Sundström & Gonçalo Castelo-Branco & Patrick Cramer & Igor Adameyko & Sten Linnarsson & Peter V. Kharchenko - 499-503 Suppression of insulin feedback enhances the efficacy of PI3K inhibitors
by Benjamin D. Hopkins & Chantal Pauli & Xing Du & Diana G. Wang & Xiang Li & David Wu & Solomon C. Amadiume & Marcus D. Goncalves & Cindy Hodakoski & Mark R. Lundquist & Rohan Bareja & Yan Ma & Emily M. Harris & Andrea Sboner & Himisha Beltran & Mark A. Rubin & Siddhartha Mukherjee & Lewis C. Cantley - 504-508 Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability
by Nahid Iglesias & Mark A. Currie & Gloria Jih & Joao A. Paulo & Nertila Siuti & Marian Kalocsay & Steven P. Gygi & Danesh Moazed - 509-512 Inositol phosphates are assembly co-factors for HIV-1
by Robert A. Dick & Kaneil K. Zadrozny & Chaoyi Xu & Florian K. M. Schur & Terri D. Lyddon & Clifton L. Ricana & Jonathan M. Wagner & Juan R. Perilla & Barbie K. Ganser-Pornillos & Marc C. Johnson & Owen Pornillos & Volker M. Vogt - 513-515 A toolkit for data transparency takes shape
by Jeffrey M. Perkel - 515-515 Software training in Antarctica
by Jeffrey M. Perkel - 517-519 How working as a research technician can bolster your scientific career
by Charlotte Schubert - 519-519 Depression tracker
by Virginia Gewin - 522-522 Breakthrough
by John Gilbey
August 2018, Volume 560, Issue 7718
- 27-27 Publisher Correction: Chromatin analysis in human early development reveals epigenetic transition during ZGA
by Jingyi Wu & Jiawei Xu & Bofeng Liu & Guidong Yao & Peizhe Wang & Zili Lin & Bo Huang & Xuepeng Wang & Tong Li & Senlin Shi & Nan Zhang & Fuyu Duan & Jia Ming & Xiangyang Zhang & Wenbin Niu & Wenyan Song & Haixia Jin & Yihong Guo & Shanjun Dai & Linli Hu & Lanlan Fang & Qiujun Wang & Yuanyuan Li & Wei Li & Jie Na & Wei Xie & Yingpu Sun - 28-28 Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation
by Simon Raffel & Mattia Falcone & Niclas Kneisel & Jenny Hansson & Wei Wang & Christoph Lutz & Lars Bullinger & Gernot Poschet & Yannic Nonnenmacher & Andrea Barnert & Carsten Bahr & Petra Zeisberger & Adriana Przybylla & Markus Sohn & Martje Tönjes & Ayelet Erez & Lital Adler & Patrizia Jensen & Claudia Scholl & Stefan Fröhling & Sibylle Cocciardi & Patrick Wuchter & Christian Thiede & Anne Flörcken & Jörg Westermann & Gerhard Ehninger & Peter Lichter & Karsten Hiller & Rüdiger Hell & Carl Herrmann & Anthony D. Ho & Jeroen Krijgsveld & Bernhard Radlwimmer & Andreas Trumpp - 29-29 Author Correction: Subepithelial telocytes are an important source of Wnts that supports intestinal crypts
by Michal Shoshkes-Carmel & Yue J. Wang & Kirk J. Wangensteen & Beáta Tóth & Ayano Kondo & Efi E. Massasa & Shalev Itzkovitz & Klaus H. Kaestner - 30-30 Author Correction: Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism
by Neelroop N. Parikshak & Vivek Swarup & T. Grant Belgard & Manuel Irimia & Gokul Ramaswami & Michael J. Gandal & Christopher Hartl & Virpi Leppa & Luis Torre Ubieta & Jerry Huang & Jennifer K. Lowe & Benjamin J. Blencowe & Steve Horvath & Daniel H. Geschwind - 283-283 Funders must be wary of industry alliances
by Linda Bauld - 289-290 War zone complicates roll-out of Ebola vaccine in latest outbreak
by Amy Maxmen - 290-291 How Unpaywall is transforming open science
by Holly Else - 291-292 Gene-silencing technology gets first drug approval after 20-year wait
by Heidi Ledford - 292-293 Industry trumps peer-reviewed science at US environment agency
by Jeff Tollefson - 293-294 LHC physicists embrace brute-force approach to particle hunt
by Davide Castelvecchi - 295-297 How digital drug users could help to halt the US opioid epidemic
by Sara Reardon - 299-301 Biologists ignore ocean weather at their peril
by Amanda E. Bates & Brian Helmuth & Michael T. Burrows & Murray I. Duncan & Joaquim Garrabou & Tamar Guy-Haim & Fernando Lima & Ana M. Queiros & Rui Seabra & Robert Marsh & Jonathan Belmaker & Nathaniel Bensoussan & Yunwei Dong & Antonios D. Mazaris & Dan Smale & Martin Wahl & Gil Rilov - 302-304 Arctic odysseys: science among sea bears and musk oxen
by Huw Lewis-Jones - 303-303 The ancient seeds of the opioid crisis, a love letter to physics, and a ticket to the termite circus: Books in brief
by Barbara Kiser - 304-305 Sex, religion and a towering treatise on anatomy
by Dániel Margócsy & Mark Somos & Stephen N. Joffe - 307-307 Speed up global ban on industrial trans fats in food
by Igor Pravst - 307-307 Engage more early-career scientists as peer reviewers
by Mathieu Casado - 307-307 Dilemma over AI and drug patenting already under debate
by Ross D. King & Patrick Courtney - 307-307 Are women the losers in team cosmology prize?
by Olivier Berné - 307-307 Bring training forward for undergraduate researchers
by John Trant - 308-308 Paul Delos Boyer (1918-2018)
by Richard L. Cross - 310-311 Enzymes team up with light-activated catalysts
by Nicholas J. Turner - 311-312 Birds perceive colours in categories
by Almut Kelber - 313-314 Profile of an unknown airway cell
by Kyle J. Travaglini & Mark A. Krasnow - 314-316 Reaction combination opens up 3D molecular diversity for drug discovery
by Wenbo Ye & Ang Li - 316-317 Special relativity validated by neutrinos
by Matthew Mewes - 317-318 Yeast chromosome numbers minimized using genome editing
by Gianni Liti - 319-324 A revised airway epithelial hierarchy includes CFTR-expressing ionocytes
by Daniel T. Montoro & Adam L. Haber & Moshe Biton & Vladimir Vinarsky & Brian Lin & Susan E. Birket & Feng Yuan & Sijia Chen & Hui Min Leung & Jorge Villoria & Noga Rogel & Grace Burgin & Alexander M. Tsankov & Avinash Waghray & Michal Slyper & Julia Waldman & Lan Nguyen & Danielle Dionne & Orit Rozenblatt-Rosen & Purushothama Rao Tata & Hongmei Mou & Manjunatha Shivaraju & Hermann Bihler & Martin Mense & Guillermo J. Tearney & Steven M. Rowe & John F. Engelhardt & Aviv Regev & Jayaraj Rajagopal - 325-330 Genetic and transcriptional evolution alters cancer cell line drug response
by Uri Ben-David & Benjamin Siranosian & Gavin Ha & Helen Tang & Yaara Oren & Kunihiko Hinohara & Craig A. Strathdee & Joshua Dempster & Nicholas J. Lyons & Robert Burns & Anwesha Nag & Guillaume Kugener & Beth Cimini & Peter Tsvetkov & Yosef E. Maruvka & Ryan O’Rourke & Anthony Garrity & Andrew A. Tubelli & Pratiti Bandopadhayay & Aviad Tsherniak & Francisca Vazquez & Bang Wong & Chet Birger & Mahmoud Ghandi & Aaron R. Thorner & Joshua A. Bittker & Matthew Meyerson & Gad Getz & Rameen Beroukhim & Todd R. Golub - 331-335 Creating a functional single-chromosome yeast
by Yangyang Shao & Ning Lu & Zhenfang Wu & Chen Cai & Shanshan Wang & Ling-Li Zhang & Fan Zhou & Shijun Xiao & Lin Liu & Xiaofei Zeng & Huajun Zheng & Chen Yang & Zhihu Zhao & Guoping Zhao & Jin-Qiu Zhou & Xiaoli Xue & Zhongjun Qin - 336-339 Ferroelectric switching of a two-dimensional metal
by Zaiyao Fei & Wenjin Zhao & Tauno A. Palomaki & Bosong Sun & Moira K. Miller & Zhiying Zhao & Jiaqiang Yan & Xiaodong Xu & David H. Cobden - 340-344 Room-temperature electrical control of exciton flux in a van der Waals heterostructure
by Dmitrii Unuchek & Alberto Ciarrocchi & Ahmet Avsar & Kenji Watanabe & Takashi Taniguchi & Andras Kis - 345-349 Cryo-STEM mapping of solid–liquid interfaces and dendrites in lithium-metal batteries
by Michael J. Zachman & Zhengyuan Tu & Snehashis Choudhury & Lynden A. Archer & Lena F. Kourkoutis - 350-354 Building C(sp3)-rich complexity by combining cycloaddition and C–C cross-coupling reactions
by Tie–Gen Chen & Lisa M. Barton & Yutong Lin & Jet Tsien & David Kossler & Iñaki Bastida & Shota Asai & Cheng Bi & Jason S. Chen & Mingde Shan & Hui Fang & Francis G. Fang & Hyeong-wook Choi & Lynn Hawkins & Tian Qin & Phil S. Baran - 355-359 Cooperative asymmetric reactions combining photocatalysis and enzymatic catalysis
by Zachary C. Litman & Yajie Wang & Huimin Zhao & John F. Hartwig - 360-364 Marine heatwaves under global warming
by Thomas L. Frölicher & Erich M. Fischer & Nicolas Gruber - 365-367 Categorical perception of colour signals in a songbird
by Eleanor M. Caves & Patrick A. Green & Matthew N. Zipple & Susan Peters & Sönke Johnsen & Stephen Nowicki - 368-371 Ecosystem warming extends vegetation activity but heightens vulnerability to cold temperatures
by Andrew D. Richardson & Koen Hufkens & Thomas Milliman & Donald M. Aubrecht & Morgan E. Furze & Bijan Seyednasrollah & Misha B. Krassovski & John M. Latimer & W. Robert Nettles & Ryan R. Heiderman & Jeffrey M. Warren & Paul J. Hanson - 372-376 Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination
by Zita Hubler & Dharmaraja Allimuthu & Ilya Bederman & Matthew S. Elitt & Mayur Madhavan & Kevin C. Allan & H. Elizabeth Shick & Eric Garrison & Molly Karl & Daniel C. Factor & Zachary S. Nevin & Joel L. Sax & Matthew A. Thompson & Yuriy Fedorov & Jing Jin & William K. Wilson & Martin Giera & Franz Bracher & Robert H. Miller & Paul J. Tesar & Drew J. Adams - 377-381 A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte
by Lindsey W. Plasschaert & Rapolas Žilionis & Rayman Choo-Wing & Virginia Savova & Judith Knehr & Guglielmo Roma & Allon M. Klein & Aron B. Jaffe - 382-386 Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response
by Gang Chen & Alexander C. Huang & Wei Zhang & Gao Zhang & Min Wu & Wei Xu & Zili Yu & Jiegang Yang & Beike Wang & Honghong Sun & Houfu Xia & Qiwen Man & Wenqun Zhong & Leonardo F. Antelo & Bin Wu & Xuepeng Xiong & Xiaoming Liu & Lei Guan & Ting Li & Shujing Liu & Ruifeng Yang & Youtao Lu & Liyun Dong & Suzanne McGettigan & Rajasekharan Somasundaram & Ravi Radhakrishnan & Gordon Mills & Yiling Lu & Junhyong Kim & Youhai H. Chen & Haidong Dong & Yifang Zhao & Giorgos C. Karakousis & Tara C. Mitchell & Lynn M. Schuchter & Meenhard Herlyn & E. John Wherry & Xiaowei Xu & Wei Guo - 387-391 A multiprotein supercomplex controlling oncogenic signalling in lymphoma
by James D. Phelan & Ryan M. Young & Daniel E. Webster & Sandrine Roulland & George W. Wright & Monica Kasbekar & Arthur L. Shaffer & Michele Ceribelli & James Q. Wang & Roland Schmitz & Masao Nakagawa & Emmanuel Bachy & Da Wei Huang & Yanlong Ji & Lu Chen & Yandan Yang & Hong Zhao & Xin Yu & Weihong Xu & Maryknoll M. Palisoc & Racquel R. Valadez & Theresa Davies-Hill & Wyndham H. Wilson & Wing C. Chan & Elaine S. Jaffe & Randy D. Gascoyne & Elias Campo & Andreas Rosenwald & German Ott & Jan Delabie & Lisa M. Rimsza & Fausto J. Rodriguez & Fayez Estephan & Matthias Holdhoff & Michael J. Kruhlak & Stephen M. Hewitt & Craig J. Thomas & Stefania Pittaluga & Thomas Oellerich & Louis M. Staudt - 392-396 Karyotype engineering by chromosome fusion leads to reproductive isolation in yeast
by Jingchuan Luo & Xiaoji Sun & Brendan P. Cormack & Jef D. Boeke - 397-400 Gamete fusion triggers bipartite transcription factor assembly to block re-fertilization
by Aleksandar Vještica & Laura Merlini & Pedro Junior Nkosi & Sophie G. Martin - 401-402 Top tips for building and maintaining international collaborations
by Virginia Gewin - 404-404 The preprint
by J. W. Armstrong
August 2018, Volume 560, Issue 7717
- 5-7 Inter-homologue repair in fertilized human eggs?
by Dieter Egli & Michael V. Zuccaro & Michael Kosicki & George M. Church & Allan Bradley & Maria Jasin - 8-9 Large deletions induced by Cas9 cleavage
by Fatwa Adikusuma & Sandra Piltz & Mark A. Corbett & Michelle Turvey & Shaun R. McColl & Karla J. Helbig & Michael R. Beard & James Hughes & Richard T. Pomerantz & Paul Q. Thomas - 10-23 Ma et al. reply
by Hong Ma & Nuria Marti-Gutierrez & Sang-Wook Park & Jun Wu & Tomonari Hayama & Hayley Darby & Crystal Van Dyken & Ying Li & Amy Koski & Dan Liang & Keiichiro Suzuki & Ying Gu & Jianhui Gong & Xun Xu & Riffat Ahmed & Yeonmi Lee & Eunju Kang & Dongmei Ji & A-Reum Park & Daesik Kim & Sang-Tae Kim & Stephen B. Heitner & David Battaglia & Sacha A. Krieg & David M. Lee & Diana H. Wu & Don P. Wolf & Paula Amato & Sanjiv Kaul & Juan Carlos Izpisua Belmonte & Jin-Soo Kim & Shoukhrat Mitalipov - 24-24 Publisher Correction: Synthesis, structure and reaction chemistry of a nucleophilic aluminyl anion
by Jamie Hicks & Petra Vasko & Jose M. Goicoechea & Simon Aldridge - 25-25 Addendum: Freezing on a sphere
by Rodrigo E. Guerra & Colm P. Kelleher & Andrew D. Hollingsworth & Paul M. Chaikin - 26-26 Author Correction: High-fat diet enhances stemness and tumorigenicity of intestinal progenitors
by Semir Beyaz & Miyeko D. Mana & Jatin Roper & Dmitriy Kedrin & Assieh Saadatpour & Sue-Jean Hong & Khristian E. Bauer-Rowe & Michael E. Xifaras & Adam Akkad & Erika Arias & Luca Pinello & Yarden Katz & Shweta Shinagare & Monther Abu-Remaileh & Maria M. Mihaylova & Dudley W. Lamming & Rizkullah Dogum & Guoji Guo & George W. Bell & Martin Selig & G. Petur Nielsen & Nitin Gupta & Cristina R. Ferrone & Vikram Deshpande & Guo-Cheng Yuan & Stuart H. Orkin & David M. Sabatini & Ömer H. Yilmaz - 143-143 Who would you share your funding with?
by Johan Bollen - 149-150 Indian scientists race to map Ganges river in 3D
by Lou Del Bello - 150-151 The wait is over: Trump taps meteorologist as White House science adviser
by Sara Reardon & Alexandra Witze - 151-152 Thousands of exotic ‘topological’ materials discovered through sweeping search
by Elizabeth Gibney - 152-153 Number-theory prodigy among winners of most coveted prize in mathematics
by Davide Castelvecchi - 153-154 Gigantic review of German science recommends more data and diversity
by Quirin Schiermeier - 156-157 The mice with human tumours: Growing pains for a popular cancer model
by Cassandra Willyard - 158-160 The ghost of influenza past and the hunt for a universal vaccine
by Declan Butler - 161-163 Human errors are behind most oil-tanker spills
by Zheng Wan & Jihong Chen - 164-164 A Jordanian biologist redefines success for women in science
by Malak Abedalthagafi - 165-165 Two slits and one hell of a quantum conundrum
by Philip Ball - 166-166 Probing the genetics of the mind
by Douwe Draaisma - 167-167 Eradicate illicit production of ozone-depleting emissions
by Hong Yang & Roger J. Flower & Julian R. Thompson - 167-167 Glacier geoengineering needs lawyers too
by Brendan Gogarty - 167-167 Warnings alone won’t protect New Caledonia wildlife from cruises
by Eric Vidal & Martin Thibault & Karen Bourgeois - 167-167 Don’t decouple Romanian universities from international excellence
by Daniel David & Bálint Markó - 170-171 Integration of optoelectronics into fibres enhances textiles
by Walter Margulis - 171-172 Drug candidate and target for leishmaniasis
by Carolina M. C. Catta-Preta & Jeremy C. Mottram - 172-174 A lymphatic waste-disposal system implicated in Alzheimer’s disease
by Melanie D. Sweeney & Berislav V. Zlokovic - 174-175 Stable and switchable electric polarization in two dimensions
by Turan Birol - 175-176 Topological states engineered in narrow strips of graphene
by Katharina J. Franke & Felix von Oppen - 176-177 Newly made mitochondrial DNA drives inflammation
by Michael P. Murphy - 179-184 Coherent spin–photon coupling using a resonant exchange qubit
by A. J. Landig & J. V. Koski & P. Scarlino & U. C. Mendes & A. Blais & C. Reichl & W. Wegscheider & A. Wallraff & K. Ensslin & T. Ihn - 185-191 Functional aspects of meningeal lymphatics in ageing and Alzheimer’s disease
by Sandro Mesquita & Antoine Louveau & Andrea Vaccari & Igor Smirnov & R. Chase Cornelison & Kathryn M. Kingsmore & Christian Contarino & Suna Onengut-Gumuscu & Emily Farber & Daniel Raper & Kenneth E. Viar & Romie D. Powell & Wendy Baker & Nisha Dabhi & Robin Bai & Rui Cao & Song Hu & Stephen S. Rich & Jennifer M. Munson & M. Beatriz Lopes & Christopher C. Overall & Scott T. Acton & Jonathan Kipnis - 192-197 Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis
by Susan Wyllie & Michael Thomas & Stephen Patterson & Sabrinia Crouch & Manu Rycker & Rhiannon Lowe & Stephanie Gresham & Michael D. Urbaniak & Thomas D. Otto & Laste Stojanovski & Frederick R. C. Simeons & Sujatha Manthri & Lorna M. MacLean & Fabio Zuccotto & Nadine Homeyer & Hannah Pflaumer & Markus Boesche & Lalitha Sastry & Paul Connolly & Sebastian Albrecht & Matt Berriman & Gerard Drewes & David W. Gray & Sonja Ghidelli-Disse & Susan Dixon & Jose M. Fiandor & Paul G. Wyatt & Michael A. J. Ferguson & Alan H. Fairlamb & Timothy J. Miles & Kevin D. Read & Ian H. Gilbert - 198-203 New mitochondrial DNA synthesis enables NLRP3 inflammasome activation
by Zhenyu Zhong & Shuang Liang & Elsa Sanchez-Lopez & Feng He & Shabnam Shalapour & Xue-jia Lin & Jerry Wong & Siyuan Ding & Ekihiro Seki & Bernd Schnabl & Andrea L. Hevener & Harry B. Greenberg & Tatiana Kisseleva & Michael Karin - 204-208 Topological band engineering of graphene nanoribbons
by Daniel J. Rizzo & Gregory Veber & Ting Cao & Christopher Bronner & Ting Chen & Fangzhou Zhao & Henry Rodriguez & Steven G. Louie & Michael F. Crommie & Felix R. Fischer - 209-213 Engineering of robust topological quantum phases in graphene nanoribbons
by Oliver Gröning & Shiyong Wang & Xuelin Yao & Carlo A. Pignedoli & Gabriela Borin Barin & Colin Daniels & Andrew Cupo & Vincent Meunier & Xinliang Feng & Akimitsu Narita & Klaus Müllen & Pascal Ruffieux & Roman Fasel - 214-218 Diode fibres for fabric-based optical communications
by Michael Rein & Valentine Dominique Favrod & Chong Hou & Tural Khudiyev & Alexander Stolyarov & Jason Cox & Chia-Chun Chung & Chhea Chhav & Marty Ellis & John Joannopoulos & Yoel Fink - 219-222 Extensive loss of past permafrost carbon but a net accumulation into present-day soils
by Amelie Lindgren & Gustaf Hugelius & Peter Kuhry - 223-227 Xenon isotopic constraints on the history of volatile recycling into the mantle
by Rita Parai & Sujoy Mukhopadhyay - 228-232 Shared evolutionary origin of vertebrate neural crest and cranial placodes
by Ryoko Horie & Alex Hazbun & Kai Chen & Chen Cao & Michael Levine & Takeo Horie - 233-237 Structure and function of the global topsoil microbiome
by Mohammad Bahram & Falk Hildebrand & Sofia K. Forslund & Jennifer L. Anderson & Nadejda A. Soudzilovskaia & Peter M. Bodegom & Johan Bengtsson-Palme & Sten Anslan & Luis Pedro Coelho & Helery Harend & Jaime Huerta-Cepas & Marnix H. Medema & Mia R. Maltz & Sunil Mundra & Pål Axel Olsson & Mari Pent & Sergei Põlme & Shinichi Sunagawa & Martin Ryberg & Leho Tedersoo & Peer Bork - 238-242 Mitochondrial double-stranded RNA triggers antiviral signalling in humans
by Ashish Dhir & Somdutta Dhir & Lukasz S. Borowski & Laura Jimenez & Michael Teitell & Agnès Rötig & Yanick J. Crow & Gillian I. Rice & Darragh Duffy & Christelle Tamby & Takayuki Nojima & Arnold Munnich & Manuel Schiff & Claudia Ribeiro Almeida & Jan Rehwinkel & Andrzej Dziembowski & Roman J. Szczesny & Nicholas J. Proudfoot - 243-247 Human glioblastoma arises from subventricular zone cells with low-level driver mutations
by Joo Ho Lee & Jeong Eun Lee & Jee Ye Kahng & Se Hoon Kim & Jun Sung Park & Seon Jin Yoon & Ji-Yong Um & Woo Kyeong Kim & June-Koo Lee & Junseong Park & Eui Hyun Kim & Ji-Hyun Lee & Joon-Hyuk Lee & Won-Suk Chung & Young Seok Ju & Sung-Hong Park & Jong Hee Chang & Seok-Gu Kang & Jeong Ho Lee - 248-252 CRISPR-guided DNA polymerases enable diversification of all nucleotides in a tunable window
by Shakked O. Halperin & Connor J. Tou & Eric B. Wong & Cyrus Modavi & David V. Schaffer & John E. Dueber - 253-257 Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth
by Jonathan B. Baell & David J. Leaver & Stefan J. Hermans & Gemma L. Kelly & Margs S. Brennan & Natalie L. Downer & Nghi Nguyen & Johannes Wichmann & Helen M. McRae & Yuqing Yang & Ben Cleary & H. Rachel Lagiakos & Stephen Mieruszynski & Guido Pacini & Hannah K. Vanyai & Maria I. Bergamasco & Rose E. May & Bethany K. Davey & Kimberly J. Morgan & Andrew J. Sealey & Beinan Wang & Natasha Zamudio & Stephen Wilcox & Alexandra L. Garnham & Bilal N. Sheikh & Brandon J. Aubrey & Karen Doggett & Matthew C. Chung & Melanie Silva & John Bentley & Pat Pilling & Meghan Hattarki & Olan Dolezal & Matthew L. Dennis & Hendrik Falk & Bin Ren & Susan A. Charman & Karen L. White & Jai Rautela & Andrea Newbold & Edwin D. Hawkins & Ricky W. Johnstone & Nicholas D. Huntington & Thomas S. Peat & Joan K. Heath & Andreas Strasser & Michael W. Parker & Gordon K. Smyth & Ian P. Street & Brendon J. Monahan & Anne K. Voss & Tim Thomas - 258-262 Cryo-EM of the dynamin polymer assembled on lipid membrane
by Leopold Kong & Kem A. Sochacki & Huaibin Wang & Shunming Fang & Bertram Canagarajah & Andrew D. Kehr & William J. Rice & Marie-Paule Strub & Justin W. Taraska & Jenny E. Hinshaw - 263-267 Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM
by Eva Kummer & Marc Leibundgut & Oliver Rackham & Richard G. Lee & Daniel Boehringer & Aleksandra Filipovska & Nenad Ban - 269-270 How to pick an electronic laboratory notebook
by Roberta Kwok - 271-273 How to work with your institution’s press office to maximize the reach of your work
by Roberta Kwok - 273-273 Earth hacker
by Virginia Gewin - 276-276 Home Cygnus
by S. R. Algernon
August 2018, Volume 560, Issue 7716
- 1-1 Author Correction: Crowther et al. reply
by T. W. Crowther & M. B. Machmuller & J. C. Carey & S. D. Allison & J. M. Blair & S. D. Bridgham & A. J. Burton & F. A. Dijkstra & B. Elberling & M. Estiarte & K. S. Larsen & H. Laudon & M. Lupascu & S. Marhan & J. Mohan & S. Niu & J. J. Peñuelas & I. K. Schmidt & P. H. Templer & G. Kröel-Dulay & S. Frey & M. A. Bradford - 2-2 Author Correction: Inflammatory memory sensitizes skin epithelial stem cells to tissue damage
by Shruti Naik & Samantha B. Larsen & Nicholas C. Gomez & Kirill Alaverdyan & Ataman Sendoel & Shaopeng Yuan & Lisa Polak & Anita Kulukian & Sophia Chai & Elaine Fuchs - 3-3 Author Correction: A molecular atlas of cell types and zonation in the brain vasculature
by Michael Vanlandewijck & Liqun He & Maarja Andaloussi Mäe & Johanna Andrae & Koji Ando & Francesca Gaudio & Khayrun Nahar & Thibaud Lebouvier & Bàrbara Laviña & Leonor Gouveia & Ying Sun & Elisabeth Raschperger & Markus Räsänen & Yvette Zarb & Naoki Mochizuki & Annika Keller & Urban Lendahl & Christer Betsholtz - 4-4 Publisher Correction: Integrating photonics with silicon nanoelectronics for the next generation of systems on a chip
by Amir H. Atabaki & Sajjad Moazeni & Fabio Pavanello & Hayk Gevorgyan & Jelena Notaros & Luca Alloatti & Mark T. Wade & Chen Sun & Seth A. Kruger & Huaiyu Meng & Kenaish Al Qubaisi & Imbert Wang & Bohan Zhang & Anatol Khilo & Christopher V. Baiocco & Miloš A. Popović & Vladimir M. Stojanović & Rajeev J. Ram - 7-7 Wildfire science is at a loss for comprehensive data
by David Bowman - 13-14 There’s water on Mars! Signs of buried lake tantalize scientists
by Alexandra Witze - 14-15 Chinese vaccine scandal unlikely to dent childhood immunization rates
by Nicky Phillips - 16-16 CRISPR plants now subject to tough GM laws in European Union
by Ewen Callaway - 17-17 Milky Way’s black hole provides long-sought test of Einstein’s general relativity
by Alexandra Witze - 17-18 Push to weaken US Endangered Species Act runs into roadblocks
by Jeremy Rehm - 20-22 Droughts, heatwaves and floods: How to tell when climate change is to blame
by Quirin Schiermeier - 23-25 Set road charges in real time to ease traffic
by Peter Cramton & R. Richard Geddes & Axel Ockenfels - 26-27 The band of biologists who redrew the tree of life
by John Archibald - 27-27 Ebola from the front lines, US aviation’s female high-fliers, and a history of science journals: Books in brief
by Barbara Kiser - 28-28 Ideal witness: a physicist takes on the world
by Robert P. Crease - 29-29 Solar power brings money to rural areas
by Yang Zhou & Yansui Liu - 29-29 Rectify biased interpretation of science history
by Aiza Kabeer & Jessica W. Tsai - 29-29 Make research-paper databases multilingual
by Daniel Prieto - 29-29 Resist calls for replicability in the humanities
by Sarah de Rijcke & Bart Penders - 29-29 Colombia’s rural development must honour peace agreement
by Luca Eufemia & Michelle Bonatti & Marcos A. Lana - 32-33 Hyperactive soil microbes might weaken the terrestrial carbon sink
by Kiona Ogle - 33-34 Peptide secretion triggers diabetes
by Jiajie Wei & Jonathan W. Yewdell - 35-35 The origin of blue diamonds
by Andrew Mitchinson - 35-36 Leukaemia follows a blood-vessel track to enter the nervous system
by Frank Winkler - 37-38 Reflection forbidden and refraction reversed in an artificial crystal
by Baile Zhang - 38-39 An unexpected trigger for calorie burning in brown fat
by Sheng Hui & Joshua D. Rabinowitz - 39-40 Developing neurons are innately inclined to learn on the job
by Christian Mayer & Gord Fishell - 41-48 Machine learning at the energy and intensity frontiers of particle physics
by Alexander Radovic & Mike Williams & David Rousseau & Michael Kagan & Daniele Bonacorsi & Alexander Himmel & Adam Aurisano & Kazuhiro Terao & Taritree Wongjirad - 49-54 Genome-centric view of carbon processing in thawing permafrost
by Ben J. Woodcroft & Caitlin M. Singleton & Joel A. Boyd & Paul N. Evans & Joanne B. Emerson & Ahmed A. F. Zayed & Robert D. Hoelzle & Timothy O. Lamberton & Carmody K. McCalley & Suzanne B. Hodgkins & Rachel M. Wilson & Samuel O. Purvine & Carrie D. Nicora & Changsheng Li & Steve Frolking & Jeffrey P. Chanton & Patrick M. Crill & Scott R. Saleska & Virginia I. Rich & Gene W. Tyson - 55-60 Leukaemia hijacks a neural mechanism to invade the central nervous system
by Hisayuki Yao & Trevor T. Price & Gaia Cantelli & Brandon Ngo & Matthew J. Warner & Lindsey Olivere & Sarah M. Ridge & Elizabeth M. Jablonski & Joseph Therrien & Stacey Tannheimer & Chad M. McCall & Anjen Chenn & Dorothy A. Sipkins - 61-64 Topological negative refraction of surface acoustic waves in a Weyl phononic crystal
by Hailong He & Chunyin Qiu & Liping Ye & Xiangxi Cai & Xiying Fan & Manzhu Ke & Fan Zhang & Zhengyou Liu - 65-69 Photoswitching topology in polymer networks with metal–organic cages as crosslinks
by Yuwei Gu & Eric A. Alt & Heng Wang & Xiaopeng Li & Adam P. Willard & Jeremiah A. Johnson - 70-75 Direct arylation of strong aliphatic C–H bonds
by Ian B. Perry & Thomas F. Brewer & Patrick J. Sarver & Danielle M. Schultz & Daniel A. DiRocco & David W. C. MacMillan - 76-79 A two-million-year-long hydroclimatic context for hominin evolution in southeastern Africa
by Thibaut Caley & Thomas Extier & James A. Collins & Enno Schefuß & Lydie Dupont & Bruno Malaizé & Linda Rossignol & Antoine Souron & Erin L. McClymont & Francisco J. Jimenez-Espejo & Carmen García-Comas & Frédérique Eynaud & Philippe Martinez & Didier M. Roche & Stephan J. Jorry & Karine Charlier & Mélanie Wary & Pierre-Yves Gourves & Isabelle Billy & Jacques Giraudeau - 80-83 Globally rising soil heterotrophic respiration over recent decades
by Ben Bond-Lamberty & Vanessa L. Bailey & Min Chen & Christopher M. Gough & Rodrigo Vargas - 84-87 Blue boron-bearing diamonds from Earth’s lower mantle
by Evan M. Smith & Steven B. Shirey & Stephen H. Richardson & Fabrizio Nestola & Emma S. Bullock & Jianhua Wang & Wuyi Wang - 88-91 Hurricane-induced selection on the morphology of an island lizard
by Colin M. Donihue & Anthony Herrel & Anne-Claire Fabre & Ambika Kamath & Anthony J. Geneva & Thomas W. Schoener & Jason J. Kolbe & Jonathan B. Losos - 92-96 Ecosystem restructuring along the Great Barrier Reef following mass coral bleaching
by Rick D. Stuart-Smith & Christopher J. Brown & Daniela M. Ceccarelli & Graham J. Edgar - 97-101 Differential tuning of excitation and inhibition shapes direction selectivity in ferret visual cortex
by Daniel E. Wilson & Benjamin Scholl & David Fitzpatrick - 102-106 Accumulation of succinate controls activation of adipose tissue thermogenesis
by Evanna L. Mills & Kerry A. Pierce & Mark P. Jedrychowski & Ryan Garrity & Sally Winther & Sara Vidoni & Takeshi Yoneshiro & Jessica B. Spinelli & Gina Z. Lu & Lawrence Kazak & Alexander S. Banks & Marcia C. Haigis & Shingo Kajimura & Michael P. Murphy & Steven P. Gygi & Clary B. Clish & Edward T. Chouchani - 107-111 Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides
by Xiaoxiao Wan & Bernd H. Zinselmeyer & Pavel N. Zakharov & Anthony N. Vomund & Ruth Taniguchi & Laura Santambrogio & Mark S. Anderson & Cheryl F. Lichti & Emil R. Unanue - 112-116 53BP1–RIF1–shieldin counteracts DSB resection through CST- and Polα-dependent fill-in
by Zachary Mirman & Francisca Lottersberger & Hiroyuki Takai & Tatsuya Kibe & Yi Gong & Kaori Takai & Alessandro Bianchi & Michal Zimmermann & Daniel Durocher & Titia Lange - 117-121 The shieldin complex mediates 53BP1-dependent DNA repair
by Sylvie M. Noordermeer & Salomé Adam & Dheva Setiaputra & Marco Barazas & Stephen J. Pettitt & Alexanda K. Ling & Michele Olivieri & Alejandro Álvarez-Quilón & Nathalie Moatti & Michal Zimmermann & Stefano Annunziato & Dragomir B. Krastev & Feifei Song & Inger Brandsma & Jessica Frankum & Rachel Brough & Alana Sherker & Sébastien Landry & Rachel K. Szilard & Meagan M. Munro & Andrea McEwan & Théo Goullet de Rugy & Zhen-Yuan Lin & Traver Hart & Jason Moffat & Anne-Claude Gingras & Alberto Martin & Haico Attikum & Jos Jonkers & Christopher J. Lord & Sven Rottenberg & Daniel Durocher - 122-127 53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ
by Hind Ghezraoui & Catarina Oliveira & Jordan R. Becker & Kirstin Bilham & Daniela Moralli & Consuelo Anzilotti & Roman Fischer & Mukta Deobagkar-Lele & Maria Sanchiz-Calvo & Elena Fueyo-Marcos & Sarah Bonham & Benedikt M. Kessler & Sven Rottenberg & Richard J. Cornall & Catherine M. Green & J. Ross Chapman - 128-132 Structures of human Patched and its complex with native palmitoylated sonic hedgehog
by Xiaofeng Qi & Philip Schmiege & Elias Coutavas & Jiawei Wang & Xiaochun Li - 133-134 Why it is not a ‘failure’ to leave academia
by Philipp Kruger - 136-136 The tail of Danny Whiskers
by Fawaz Al-Matrouk
July 2018, Volume 559, Issue 7715
- 1-1 Alzheimer’s disease
by Richard Hodson - 2-3 An age-old story of dementia
by Liam Drew - 4-7 The amyloid hypothesis on trial
by Simon Makin - 8-9 Drawing on the brain’s resilience to fight Alzheimer’s disease
by Lauren Gravitz - 10-12 Alzheimer’s disease is getting easier to spot
by Elie Dolgin - 11-11 Author Correction: EWS–FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma
by Aparna Gorthi & July Carolina Romero & Eva Loranc & Lin Cao & Liesl A. Lawrence & Elicia Goodale & Amanda Balboni Iniguez & Xavier Bernard & V. Pragathi Masamsetti & Sydney Roston & Elizabeth R. Lawlor & Jeffrey A. Toretsky & Kimberly Stegmaier & Stephen L. Lessnick & Yidong Chen & Alexander J. R. Bishop - 13-13 Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation
by Dimitre R. Simeonov & Benjamin G. Gowen & Mandy Boontanrart & Theodore L. Roth & John D. Gagnon & Maxwell R. Mumbach & Ansuman T. Satpathy & Youjin Lee & Nicolas L. Bray & Alice Y. Chan & Dmytro S. Lituiev & Michelle L. Nguyen & Rachel E. Gate & Meena Subramaniam & Zhongmei Li & Jonathan M. Woo & Therese Mitros & Graham J. Ray & Gemma L. Curie & Nicki Naddaf & Julia S. Chu & Hong Ma & Eric Boyer & Frederic Gool & Hailiang Huang & Ruize Liu & Victoria R. Tobin & Kathrin Schumann & Mark J. Daly & Kyle K. Farh & K. Mark Ansel & Chun J. Ye & William J. Greenleaf & Mark S. Anderson & Jeffrey A. Bluestone & Howard Y. Chang & Jacob E. Corn & Alexander Marson - 13-15 The search for better animal models of Alzheimer’s disease
by Anthony King - 16-17 Ways to stop the spread of Alzheimer’s disease
by Moheb Costandi - 18-20 How the evidence stacks up for preventing Alzheimer’s disease
by Emily Sohn - 445-445 Preprints could promote confusion and distortion
by Tom Sheldon - 451-452 Ecologists try to speed up evolution to save Australian marsupial from toxic toads
by April Reese - 452-453 Death-defying NASA mission will make humanity’s closest approach to the Sun
by Alexandra Witze - 453-454 Philippines sweetens deal for scientists who return home
by Andrew Silver - 454-455 Dutch publishing giant cuts off researchers in Germany and Sweden
by Holly Else - 455-456 Big Bang telescope finale marks end of an era in cosmology
by Davide Castelvecchi - 458-465 How to defuse malaria’s ticking time bomb
by Amy Maxmen - 467-470 Ten years left to redesign lithium-ion batteries
by Kostiantyn Turcheniuk & Dmitry Bondarev & Vinod Singhal & Gleb Yushin - 470-472 Pet genomics medicine runs wild
by Lisa Moses & Steve Niemi & Elinor Karlsson - 473-475 Ancient dreams of intelligent machines: 3,000 years of robots
by Stephen Cave & Kanta Dihal - 475-475 The souls of deserts, a gathering of visionary biologists, and an inside view on exoplanets: Books in brief
by Barbara Kiser - 477-477 Modelling the trajectory of disease outbreaks works
by Caitlin M. Rivers & Samuel V. Scarpino - 477-477 From literature search to vaccine candidate without a lab
by Reza Forough & Mohammad Mian & Anthony Klobas & Jeffrey Talada - 477-477 The United States will lose money if it charges for Earth observation data
by Barbara J. Ryan - 477-477 Don’t ignore health-care impacts of Internet shutdowns
by Okwen Mbah & Miriam Nkangu & Zak Rogoff - 480-481 An early hominin arrival in Asia
by John Kappelman - 481-482 Quantum optics without photons
by Alejandro González Tudela & J. Ignacio Cirac - 482-484 Viruses cooperate to defeat bacteria
by Aude Bernheim & Rotem Sorek - 484-485 Histidine metabolism boosts cancer therapy
by Christian Frezza - 485-487 Neural circuit evolved to process pheromone differently in two species of fruit fly
by Nicolas Gompel & Benjamin Prud’homme - 487-488 Ancient ice sheet had a growth spurt
by Pippa Whitehouse - 489-489 Tropics
by Anna Armstrong & I-han Chou & Juliane Mossinger & Clare Thomas & Christina Tobin Kårlström & Michael White - 490-497 Challenges and opportunities in controlling mosquito-borne infections
by Neil M. Ferguson - 498-506 Challenges and recent progress in drug discovery for tropical diseases
by Manu Rycker & Beatriz Baragaña & Suzanne L. Duce & Ian H. Gilbert - 507-516 Acting on non-communicable diseases in low- and middle-income tropical countries
by Majid Ezzati & Jonathan Pearson-Stuttard & James E. Bennett & Colin D. Mathers - 517-526 The future of hyperdiverse tropical ecosystems
by Jos Barlow & Filipe França & Toby A. Gardner & Christina C. Hicks & Gareth D. Lennox & Erika Berenguer & Leandro Castello & Evan P. Economo & Joice Ferreira & Benoit Guénard & Cecília Gontijo Leal & Victoria Isaac & Alexander C. Lees & Catherine L. Parr & Shaun K. Wilson & Paul J. Young & Nicholas A. J. Graham - 527-534 The tropical forest carbon cycle and climate change
by Edward T. A. Mitchard - 535-545 El Niño–Southern Oscillation complexity
by Axel Timmermann & Soon-Il An & Jong-Seong Kug & Fei-Fei Jin & Wenju Cai & Antonietta Capotondi & Kim M. Cobb & Matthieu Lengaigne & Michael J. McPhaden & Malte F. Stuecker & Karl Stein & Andrew T. Wittenberg & Kyung-Sook Yun & Tobias Bayr & Han-Ching Chen & Yoshimitsu Chikamoto & Boris Dewitte & Dietmar Dommenget & Pamela Grothe & Eric Guilyardi & Yoo-Geun Ham & Michiya Hayashi & Sarah Ineson & Daehyun Kang & Sunyong Kim & WonMoo Kim & June-Yi Lee & Tim Li & Jing-Jia Luo & Shayne McGregor & Yann Planton & Scott Power & Harun Rashid & Hong-Li Ren & Agus Santoso & Ken Takahashi & Alexander Todd & Guomin Wang & Guojian Wang & Ruihuang Xie & Woo-Hyun Yang & Sang-Wook Yeh & Jinho Yoon & Elke Zeller & Xuebin Zhang - 547-555 Machine learning for molecular and materials science
by Keith T. Butler & Daniel W. Davies & Hugh Cartwright & Olexandr Isayev & Aron Walsh - 556-563 Niobium tungsten oxides for high-rate lithium-ion energy storage
by Kent J. Griffith & Kamila M. Wiaderek & Giannantonio Cibin & Lauren E. Marbella & Clare P. Grey - 564-569 Evolution of a central neural circuit underlies Drosophila mate preferences
by Laura F. Seeholzer & Max Seppo & David L. Stern & Vanessa Ruta - 570-574 Cryo-EM structure of a fungal mitochondrial calcium uniporter
by Nam X. Nguyen & Jean-Paul Armache & Changkeun Lee & Yi Yang & Weizhong Zeng & Vamsi K. Mootha & Yifan Cheng & Xiao-chen Bai & Youxing Jiang - 575-579 X-ray and cryo-EM structures of the mitochondrial calcium uniporter
by Chao Fan & Minrui Fan & Benjamin J. Orlando & Nathan M. Fastman & Jinru Zhang & Yan Xu & Melissa G. Chambers & Xiaofang Xu & Kay Perry & Maofu Liao & Liang Feng - 580-584 Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters
by Rozbeh Baradaran & Chongyuan Wang & Andrew Francis Siliciano & Stephen Barstow Long - 585-588 The formation of solar-neighbourhood stars in two generations separated by 5 billion years
by Masafumi Noguchi - 589-592 Spontaneous emission of matter waves from a tunable open quantum system
by Ludwig Krinner & Michael Stewart & Arturo Pazmiño & Joonhyuk Kwon & Dominik Schneble