Science-Based Business : Knowledge Capital or Entrepreneurial Ability? : Theory and Evidence from a Survey of Biotechnology Start-ups
AbstractWe present a model of science-based entrepreneurship where ideas initially produced by researchers with high-level knowledge capital may be developed by high-ability entrepreneurs. With moderate investment costs, startups continuously managed by inventors-founders coexist in equilibrium with startups that experience entrepreneurial turnover. The model predicts that startups managed by non-founder entrepreneurs would on average outperform the startups managed by their founders and that better functioning of the market for entrepreneurial talent should result in more entrepreneurial turnover in equilibrium which in its turn leads to more ideas being commercialized and higher rewards to successful startups. The predictions of the model are tested against a unique dataset drawing upon a representative sample of biotechnology startups in Japan and are found to be broadly supported in the data.
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Bibliographic InfoPaper provided by Institute of Innovation Research, Hitotsubashi University in its series IIR Working Paper with number 10-05.
Length: 49 p.
Date of creation: Sep 2010
Date of revision:
Science-based Business; Biotechnology; Start-ups; Entrepreneurship; Innovation;
Other versions of this item:
- Yuji Honjo & Sadao Nagaoka & Kenta Nakamura & Serguey Braguinsky, 2011. "Science-Based Business: Knowledge Capital or Entrepreneurial Ability? Theory and Evidence from a Survey of Biotechnology Start-ups," 2011 Meeting Papers 1270, Society for Economic Dynamics.
- O31 - Economic Development, Technological Change, and Growth - - Technological Change; Research and Development; Intellectual Property Rights - - - Innovation and Invention: Processes and Incentives
- O32 - Economic Development, Technological Change, and Growth - - Technological Change; Research and Development; Intellectual Property Rights - - - Management of Technological Innovation and R&D
This paper has been announced in the following NEP Reports:
- NEP-ALL-2010-09-11 (All new papers)
- NEP-CSE-2010-09-11 (Economics of Strategic Management)
- NEP-ENT-2010-09-11 (Entrepreneurship)
- NEP-INO-2010-09-11 (Innovation)
- NEP-KNM-2010-09-11 (Knowledge Management & Knowledge Economy)
- NEP-SBM-2010-09-11 (Small Business Management)
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- Joshua S. Gans & David H. Hsu & Scott Stern, 2002.
"When Does Start-Up Innovation Spur the Gale of Creative Destruction?,"
RAND Journal of Economics,
The RAND Corporation, vol. 33(4), pages 571-586, Winter.
- Joshua S. Gans & David H. Hsu & Scott Stern, 2000. "When Does Start-Up Innovation Spur the Gale of Creative Destruction?," NBER Working Papers 7851, National Bureau of Economic Research, Inc.
- Ashish Arora & Anand Nandkumar, 2009.
"Cash-out or flame-out! Opportunity cost and entrepreneurial strategy: Theory, and evidence from the information security industry,"
NBER Working Papers
15532, National Bureau of Economic Research, Inc.
- Ashish Arora & Anand Nandkumar, 2011. "Cash-Out or Flameout! Opportunity Cost and Entrepreneurial Strategy: Theory, and Evidence from the Information Security Industry," Management Science, INFORMS, vol. 57(10), pages 1844-1860, October.
- Jerry G. Thursby & Marie C. Thursby, 2000.
"Who is Selling the Ivory Tower? Sources of Growth in University Licensing,"
NBER Working Papers
7718, National Bureau of Economic Research, Inc.
- Jerry G. Thursby & Marie C. Thursby, 2002. "Who Is Selling the Ivory Tower? Sources of Growth in University Licensing," Management Science, INFORMS, vol. 48(1), pages 90-104, January.
- Steven N. Kaplan & Per Stromberg, 2001. "Venture Capitalists As Principals: Contracting, Screening, and Monitoring," NBER Working Papers 8202, National Bureau of Economic Research, Inc.
- Thomas Hellmann, 1998. "The Allocation of Control Rights in Venture Capital Contracts," RAND Journal of Economics, The RAND Corporation, vol. 29(1), pages 57-76, Spring.
- Boyan Jovanovic & Serguey Braguinsky, 2004.
"Bidder Discounts and Target Premia in Takeovers,"
American Economic Review,
American Economic Association, vol. 94(1), pages 46-56, March.
- Jonathan B. Berk, 2004. "Valuation and Return Dynamics of New Ventures," Review of Financial Studies, Society for Financial Studies, vol. 17(1), pages 1-35.
- Marie Thursby & Richard Jensen, 2001. "Proofs and Prototypes for Sale: The Licensing of University Inventions," American Economic Review, American Economic Association, vol. 91(1), pages 240-259, March.
- Brickley, James A., 2003. "Empirical research on CEO turnover and firm-performance: a discussion," Journal of Accounting and Economics, Elsevier, vol. 36(1-3), pages 227-233, December.
- Serguey Braguinsky & Steven Klepper & Atsushi Ohyama, 2012. "High-Tech Entrepreneurship," Journal of Law and Economics, University of Chicago Press, vol. 55(4), pages 869 - 900.
- Weisbach, Michael S., 1988. "Outside directors and CEO turnover," Journal of Financial Economics, Elsevier, vol. 20(1-2), pages 431-460, January.
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