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Costs, Quality of Life and Disease Severity in Multiple Sclerosis - A Population-Based Cross-Sectional Study in Sweden

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Author Info

  • Henriksson, Freddie

    ()
    (Dept. of Economics, Stockholm School of Economics)

  • Fredrikson, Sten

    (Division of Neurology)

  • Jönsson, Bengt

    ()
    (Dept. of Economics, Stockholm School of Economics)

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    Abstract

    This study has used a cross-sectional, 'bottom-up' design to determine the cost to society of multiple sclerosis (MS) in Sweden in 1998. The total cost of MS was estimated at 4 868 MSEK, meaning an annual cost of 442 500 SEK per patient. Direct costs accounted for about 67% of total cost, and direct costs were dominated by the cost of personal assistants and drugs. Indirect costs accounted for about 33% of total costs and were totally dominated by the cost of long-term sickness absence from work and early retirement. Intangible costs were estimated at 2 700 MSEK. A former Swedish study on MS for 1994, using main diagnosis to calculate costs, showed the total cost to be 1 736 MSEK. Increased disability as measured by EDSS was found to have a major impact on the cost of the disease and on quality of life. Both direct, indirect and informal care costs rose significantly with increased EDSS and were higher during a relapse. Quality of life declined substantially with increased EDSS and was lower during a relapse. In summary, this study showed that a severe, chronic, disabling disease like MS that strikes early in life has major implications for both the society as a whole and for the affected patients.

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    Bibliographic Info

    Paper provided by Stockholm School of Economics in its series Working Paper Series in Economics and Finance with number 361.

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    Length: 42 pages
    Date of creation: 06 Mar 2000
    Date of revision:
    Handle: RePEc:hhs:hastef:0361

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    Postal: The Economic Research Institute, Stockholm School of Economics, P.O. Box 6501, 113 83 Stockholm, Sweden
    Phone: +46-(0)8-736 90 00
    Fax: +46-(0)8-31 01 57
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    Web page: http://www.hhs.se/
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    Related research

    Keywords: Multiple sclerosis; cost-of-illness; quality of life; EDSS; utility;

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    1. Niklas Zethraeus & Magnus Johannesson, 1999. "A comparison of patient and social tariff values derived from the time trade-off method," Health Economics, John Wiley & Sons, Ltd., vol. 8(6), pages 541-545.
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