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METANDI: Stata module to perform meta-analysis of diagnostic accuracy

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Author Info
Roger Harbord () (Department of Social Medicine, University of Bristol)

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Abstract

metandi performs meta-analysis of diagnostic test accuracy studies in which both the index test under study and the reference test (gold standard) are dichotomous. It fits a two-level mixed logistic regression model, with independent binomial distributions for the true positives and true negatives within each study, and a bivariate normal model for the logit transforms of sensitivity and specificity between studies. Estimates are displayed for the parameters of both the bivariate model (Reitsma et al. 2005) and the Hierarchical Summary Receiver Operating Characteristic (HSROC) model (Rutter & Gatsonis 2001). In the models without covariates fitted by metandi these are different parameterisations of the same model (Harbord et al. 2007, Arends 2006). In Stata 8 or 9 metandi makes use of the user-written command gllamm, which must also be installed. In Stata 10 metandi fits the model using the built-in command xtmelogit by default, so gllamm is not required.

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Publisher Info
Software component provided by Boston College Department of Economics in its series Statistical Software Components with number S456932.

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Programming language: Stata
Requires: Stata version 8.2
Date of creation: 16 Apr 2008
Date of revision:
Handle: RePEc:boc:bocode:s456932

Note: This module may be installed from within Stata by typing "ssc install metandi". Windows users should not attempt to download these files with a web browser.
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Postal: Boston College, 140 Commonwealth Avenue, Chestnut Hill MA 02467 USA
Phone: 617-552-3670
Fax: +1-617-552-2308
Email:
Web page: http://fmwww.bc.edu/EC/
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Related research
Keywords: diagnostic accuracy meta-analysis sensitivity and specificity hierarchical models HSROC bivariate gllamm xtmelogit

Statistics
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This page was last updated on 2008-7-24.


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