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Association Between Measures of Fatigue and Health-Related Quality of Life in Rheumatoid Arthritis and Osteoarthritis

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Author Info
Marita Cross (Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, New South Wales, Australia)
Helen Lapsley (Centre for National Research on Disability, University of Queensland, Brisbane, Queensland, Australia)
Annica Barcenilla (Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, New South Wales, Australia)
Peter Brooks (Health Sciences, University of Queensland, Brisbane, Queensland, Australia)
Lyn March (Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, New South Wales, Australia)
Abstract

Objective: To assess the relationship between fatigue and health-related quality of life (HR-QOL) among people with osteoarthritis (OA) and rheumatoid arthritis (RA). Methods: Community-dwelling people with OA, and OA patients on the waiting list for joint replacement surgery, were recruited. RA patients were recruited from rheumatologists' public and private outpatient clinics. Respondents completed a questionnaire containing demographic detail, the Fatigue Severity Scale (FSS), the Multidimensional Assessment of Fatigue (MAF), the SF-36, Western Ontario and McMaster Universities Osteoarthritis Index, and the Health Assessment Questionnaire (HAQ). Results: There were 137 OA and 52 RA respondents. Neither age nor sex was significantly associated with fatigue for OA or RA. The mean FSS score was 3.36 for RA and 3.63 for OA. Fifty percent of respondents with RA and 58% of those with OA met the FSS >3 cut-point for fatigue. Mean MAF Global Fatigue Index was 20.8 for OA and 20.1 for RA. Correlations between health status and fatigue indicated that for both OA and RA those with greater fatigue reported worse health status. Conclusions: Few studies have measured the impact of fatigue among respondents with OA, despite it affecting a large proportion of the population. Fatigue was significantly correlated with poorer HR-QOL among OA respondents, suggesting that fatigue is a significant issue in OA as well as RA.

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Publisher Info
Article provided by Wolters Kluwer Health | Adis in its journal The Patient - Patient-Centered Outcomes Research.

Volume (Year): 1 (2008)
Issue (Month): 2 ()
Pages: 97-104
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Handle: RePEc:wkh:thepat:v:1:y:2008:i:2:p:97-104

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Related research
Keywords: Fatigue; Osteoarthritis; Quality-of-life; Rheumatoid-arthritis;

Find related papers by JEL classification:
C - Mathematical and Quantitative Methods
D - Microeconomics
I - Health, Education, and Welfare
Z - Other Special Topics
I1 - Health, Education, and Welfare - - Health
I19 - Health, Education, and Welfare - - Health - - - Other
I18 - Health, Education, and Welfare - - Health - - - Government Policy; Regulation; Public Health
I11 - Health, Education, and Welfare - - Health - - - Analysis of Health Care Markets

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