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Prevention of Recurrent Rhinopharyngitis in At-Risk Children in France: A Cost-Effectiveness Model for a Nonspecific Immunostimulating Bacterial Extract (OM-85 BV)

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Author Info

  • Jean-Jacques Pessey

    (ENT Ward, Facial Surgery, University Hospital of Rangueuil, Toulouse, France)

  • Francoise Megas

    (Mapi Values, Lyon, France)

  • Benoit Arnould

    (Mapi Values, Lyon, France)

  • Florence Baron-Papillon

    (Mapi Values, Lyon, France)

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    Abstract

    Objective: To estimate the pharmacoeconomic impact for the French Social Security System of preventing recurrent acute rhinopharyngitis (RARP) in at-risk children with OM-85 BV, an immunostimulating agent indicated for the prevention of recurrences. Design: A decision-analysis model. The probability of progression of the infection and of its associated care, the principal direct costs linked to them, and the effectiveness of OM-85 BV were established or calculated by reviewing the available literature (published between 1984 and 2000). Four experts validated the parameters and the model. Results: For the French Social Security System, the mean direct cost for an acute rhinopharyngitis (ARP) infection was Conclusion: Non-specific immunotherapy should be considered for the child at risk of RARP and administered in addition to other recommended measures. The economic savings for the community of using a medication for which the clinical effectiveness has been demonstrated should also be taken into account in assessing its usefulness.

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    Bibliographic Info

    Article provided by Springer Healthcare | Adis in its journal PharmacoEconomics.

    Volume (Year): 21 (2003)
    Issue (Month): 14 ()
    Pages: 1053-1068
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    Handle: RePEc:wkh:phecon:v:21:y:2003:i:14:p:1053-1068

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    Web page: http://pharmacoeconomics.adisonline.com/

    For corrections or technical questions regarding this item, or to correct its listing, contact: (Dave Dustin).

    Related research

    Keywords: Antibronchitic-bacterial-vaccine; Children; Cost-effectiveness; Otorhinolaryngological-infections; Pharmacoeconomics; Vaccines;

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