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Knowledge spillovers in biotechnology: sources and incentives

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Author Info

  • David B. Audretsch

    () (Indiana University, Institute for Development Strategies, SPEA, Bloomington, IN 47405-2100, USA)

  • Paula E. Stephan

    (School of Policy Studies, Georgia State University, Atlanta, 6A 30303, USA)

Abstract

This paper sheds light on the questions, Why does knowledge spill over? and How does knowledge spill over? The answer to these questions we suggest lies in the incentives confronting scientists to appropriate the expected value of their knowledge considered in the context of their path-dependent career trajectories. In particular, we focus on the ability of scientists to appropriate the value of knowledge embedded in their human capital along with the incentive structure influencing if and how scientists choose to commercialize their knowledge. We conclude that the spillover of knowledge from the source creating it, such as a university, research institute, or industrial corporation, to a new-firm startup facilitates the appropriation of knowledge for the individual scientist(s) but not necessarily for the organization creating that new knowledge in the first place.

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Bibliographic Info

Article provided by Springer in its journal Journal of Evolutionary Economics.

Volume (Year): 9 (1999)
Issue (Month): 1 ()
Pages: 97-107

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Handle: RePEc:spr:joevec:v:9:y:1999:i:1:p:97-107

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Web page: http://link.springer.de/link/service/journals/00191/index.htm

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Related research

Keywords: Biotechnology ; Knowledge spillovers ; Science ; Entrepreneurship ; Startups;

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Cited by:
  1. Lam, Alice, 2011. "What motivates academic scientists to engage in research commercialization: ‘Gold’, ‘ribbon’ or ‘puzzle’?," Research Policy, Elsevier, vol. 40(10), pages 1354-1368.
  2. David Catherine & Frédéric Corolleur & Myriam Carrère & Vincent Mangematin, 2004. "Turning scientific and technological human capital into economic capital: the experience of biotech start-ups in France," Grenoble Ecole de Management (Post-Print) hal-00422583, HAL.
  3. Audretsch, David B. & Hülsbeck, Marcel & Lehmann, Erik E., 2010. "Regional competitiveness, university spillovers and entrepreneurial activity," UO Working Papers 02-10, University of Augsburg, Chair of Management and Organization.
  4. Michael Fritsch & Viktor Slavtchev, 2007. "Universities and Innovation in Space," Industry & Innovation, Taylor and Francis Journals, vol. 14(2), pages 201-218.
  5. Bozeman, Barry & Rogers, Juan D., 2002. "A churn model of scientific knowledge value: Internet researchers as a knowledge value collective," Research Policy, Elsevier, vol. 31(5), pages 769-794, July.
  6. Elicia Maine & Daniel Shapiro & Aidan Vining, 2010. "The role of clustering in the growth of new technology-based firms," Small Business Economics, Springer, vol. 34(2), pages 127-146, February.
  7. Breschi, Stefano & Catalini, Christian, 2010. "Tracing the links between science and technology: An exploratory analysis of scientists' and inventors' networks," Research Policy, Elsevier, vol. 39(1), pages 14-26, February.
  8. Michael Fritsch & Viktor Slavtchev, 2005. "The Role of Regional Knowledge for Innovation," ERSA conference papers ersa05p623, European Regional Science Association.
  9. Coronado, Daniel & Acosta, Manuel & Fernández, Ana, 2008. "Attitudes to innovation in peripheral economic regions," Research Policy, Elsevier, vol. 37(6-7), pages 1009-1021, July.
  10. Norio Sawabe & Susumu Egashira, 2007. "The knowledge management strategy and the formation of innovative networks in emerging industries," Journal of Evolutionary Economics, Springer, vol. 17(3), pages 277-298, June.
  11. Audretsch, David B & Lehmann, Erik E & Warning, Susanne, 2003. "University Spillovers: Strategic Location and New Firm Performance," CEPR Discussion Papers 3837, C.E.P.R. Discussion Papers.
  12. Slavtchev, Viktor & Fritsch, Michael, 2005. "The Role of Regional Knowledge Sources for Innovation: An Empirical Assessment," Freiberg Working Papers 2005,15, TU Bergakademie Freiberg, Faculty of Economics and Business Administration.
  13. Toole, Andrew A. & Czarnitzki, Dirk, 2007. "Life Scientist Mobility from Academe to Industry: Does Academic Entrepreneurship Induce a Costly ?Brain Drain? on the Not-for-Profit Research Sector?," ZEW Discussion Papers 07-072, ZEW - Zentrum für Europäische Wirtschaftsforschung / Center for European Economic Research.
  14. Zellner, Christian, 2003. "The economic effects of basic research: evidence for embodied knowledge transfer via scientists' migration," Research Policy, Elsevier, vol. 32(10), pages 1881-1895, December.
  15. Silveira, José Maria F. J. da, 2002. "Biotecnologia: corporações, financiamento da inovação e novas formas organizacionais," Revista Economia e Sociedade, Instituto de Economia, Universidade Estadual de Campinas (UNICAMP), vol. 18, pages 36, January.
  16. David Audretsch & Erik Lehmann, 2006. "Do locational spillovers pay? empirical evidence from German IPO data," Economics of Innovation and New Technology, Taylor and Francis Journals, vol. 15(1), pages 71-81.
  17. Gustavo Crespi & Aldo Geuna & Lionel Nesta, 2007. "The mobility of university inventors in Europe," The Journal of Technology Transfer, Springer, vol. 32(3), pages 195-215, June.

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