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The contribution of (not so) public research to commercial innovations in the field of combinatorial chemistry

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  • Malo, Stéphane

Abstract

This paper examines the roles that publicly funded research play in the process of combinatorial drug discovery. It is shown that firms rely heavily on public research knowledge and, even more so, on education in organic chemistry, genomics and biochemistry. Publicly funded research also led to the creation of dozens of chemical-based companies, provided firms with an access to a larger network of innovators and generated important instruments and methods that are being used throughout the value chain of combinatorial drug discovery. The effects of public research, however, often look different depending on whether one sees them through the prism of larger or smaller firms, EU15 countries or the US, universities or other PROs.

Suggested Citation

  • Malo, Stéphane, 2009. "The contribution of (not so) public research to commercial innovations in the field of combinatorial chemistry," Research Policy, Elsevier, vol. 38(6), pages 957-970, July.
    • Handle: RePEc:eee:respol:v:38:y:2009:i:6:p:957-970
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    Cited by:

    1. David Minguillo & Mike Thelwall, 2015. "Which are the best innovation support infrastructures for universities? Evidence from R&D output and commercial activities," Scientometrics, Springer;Akadémiai Kiadó, vol. 102(1), pages 1057-1081, January.
    2. James A. Cunningham & Vincent Mangematin & Conor O’Kane & Paul O’Reilly, 2016. "At the frontiers of scientific advancement: the factors that influence scientists to become or choose to become publicly funded principal investigators," The Journal of Technology Transfer, Springer, vol. 41(4), pages 778-797, August.
    3. John Hagedoorn & Boris Lokshin & Stéphane Malo, 2018. "Alliances and the innovation performance of corporate and public research spin-off firms," Small Business Economics, Springer, vol. 50(4), pages 763-781, April.
    4. Prettner, Klaus & Werner, Katharina, 2016. "Why it pays off to pay us well: The impact of basic research on economic growth and welfare," Research Policy, Elsevier, vol. 45(5), pages 1075-1090.
    5. Toole, Andrew A., 2012. "The impact of public basic research on industrial innovation: Evidence from the pharmaceutical industry," Research Policy, Elsevier, vol. 41(1), pages 1-12.
    6. Toole, Andrew A., 2011. "The impact of public basic research on industrial innovation: Evidence from the pharmaceutical industry," ZEW Discussion Papers 11-063, ZEW - Leibniz Centre for European Economic Research.
    7. Charlotte Schlump & Thomas Brenner, 2013. "Firm's cooperation activities: The relevance of public research, proximity and personal ties - A study of technology-oriented firms in East Germany," Working Papers on Innovation and Space 2013-06, Philipps University Marburg, Department of Geography.

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