IDEAS home Printed from https://ideas.repec.org/a/bpj/erjour/v2y2012i2n1.html
   My bibliography  Save this article

A Study of Gene-Environment Interactions In Entrepreneurship

Author

Listed:
  • Quaye Lydia

    (King’s College London)

  • Nicolaou Nicos

    (University of Cyprus & Cass Business School, City University)

  • Shane Scott

    (Case Western Reserve University)

  • Harris Juliette

    (King’s College London)

Abstract

We examined the interactions between four genes associated with dyslexia (ROBO1, KIAA0319, DCDC2, DYX1C1) and education on the tendency to become an entrepreneur. We used a two-staged design consisting of a discovery sample of 692 individuals, and a replication sample of 797 participants from the TwinsUK cohort. Associations were identified between entrepreneurship and interactions of education and ROBO1 rs654867 and KIAA0319 rs6902039 with the stage 1 samples. However these were not independently replicated and the associations were no longer significant when the samples from the 2 stages were combined. A tagging SNP approach was used to investigate the effect of the interactions between education and 191 tagging SNPs from the candidate genes on entrepreneurship. While we found several significant interactions (DCDC2, KIAA0319 and ROBO1), none passed the stringent threshold for significance of a Bonferroni correction. Similar to the case with other behavioural genetics phenotypes, large sample sizes will be required to identify significant gene-environment interactions in entrepreneurship after making Bonferroni corrections.

Suggested Citation

  • Quaye Lydia & Nicolaou Nicos & Shane Scott & Harris Juliette, 2012. "A Study of Gene-Environment Interactions In Entrepreneurship," Entrepreneurship Research Journal, De Gruyter, vol. 2(2), pages 1-20, March.
    • Handle: RePEc:bpj:erjour:v:2:y:2012:i:2:n:1
    DOI: 10.1515/2157-5665.1053
    as

    Download full text from publisher

    File URL: https://doi.org/10.1515/2157-5665.1053
    Download Restriction: For access to full text, subscription to the journal or payment for the individual article is required.
    File URL: https://libkey.io/10.1515/2157-5665.1053?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Mesch, Gustavo S. & Czamanski, Daniel, 1997. "Occupational closure and immigrant entrepreneurship: Russian Jews in Israel," Journal of Behavioral and Experimental Economics (formerly The Journal of Socio-Economics), Elsevier, vol. 26(6), pages 597-610.
    2. Edward C. Norton & Hua Wang & Chunrong Ai, 2004. "Computing interaction effects and standard errors in logit and probit models," Stata Journal, StataCorp LP, vol. 4(2), pages 154-167, June.
    3. Nicos Nicolaou & Scott Shane & Lynn Cherkas & Janice Hunkin & Tim D. Spector, 2008. "Is the Tendency to Engage in Entrepreneurship Genetic?," Management Science, INFORMS, vol. 54(1), pages 167-179, January.
    4. Ai, Chunrong & Norton, Edward C., 2003. "Interaction terms in logit and probit models," Economics Letters, Elsevier, vol. 80(1), pages 123-129, July.
    5. Frederic Delmar & Per Davidsson, 2000. "Where do they come from? Prevalence and characteristics of nascent entrepreneurs," Entrepreneurship & Regional Development, Taylor & Francis Journals, vol. 12(1), pages 1-23, January.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Krammer, Sorin M.S. & Gören, Erkan, 2021. "Wired in? Genetic traits and entrepreneurship around the world," Technological Forecasting and Social Change, Elsevier, vol. 168(C).
    2. Shane, Scott & Nicolaou, Nicos, 2015. "Creative personality, opportunity recognition and the tendency to start businesses: A study of their genetic predispositions," Journal of Business Venturing, Elsevier, vol. 30(3), pages 407-419.
    3. Graciela Kuechle, 2019. "The contribution of behavior genetics to entrepreneurship: An evolutionary perspective," Journal of Evolutionary Economics, Springer, vol. 29(4), pages 1263-1284, September.
    4. Nicos Nicolaou & Phillip H. Phan & Ute Stephan, 2021. "The Biological Perspective in Entrepreneurship Research," Entrepreneurship Theory and Practice, , vol. 45(1), pages 3-17, January.
    5. Nicos Nicolaou & Pankaj C. Patel & Marcus T. Wolfe, 2018. "Testosterone and Tendency to Engage in Self-Employment," Management Science, INFORMS, vol. 64(4), pages 1825-1841, April.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Zvonimir Bašić & Parampreet C. Bindra & Daniela Glätzle-Rützler & Angelo Romano & Matthias Sutter & Claudia Zoller, 2021. "The Roots of Cooperation," ECONtribute Discussion Papers Series 097, University of Bonn and University of Cologne, Germany.
    2. Sakaue, Katsuki, 2018. "Informal fee charge and school choice under a free primary education policy: Panel data evidence from rural Uganda," International Journal of Educational Development, Elsevier, vol. 62(C), pages 112-127.
    3. Carolin Bock & Maximilian Schmidt, 2015. "Should I stay, or should I go? – How fund dynamics influence venture capital exit decisions," Review of Financial Economics, John Wiley & Sons, vol. 27(1), pages 68-82, November.
    4. Duong, Huu Nhan & Kalev, Petko S., 2013. "Anonymity and order submissions," Pacific-Basin Finance Journal, Elsevier, vol. 25(C), pages 101-118.
    5. Chenxi Zhou & Jinhong Xie & Qi Wang, 2016. "Failure to Complete Cross-Border M&As: “To” vs. “From” Emerging Markets," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 47(9), pages 1077-1105, December.
    6. Janus, Thorsten & Riera-Crichton, Daniel, 2015. "Economic shocks, civil war and ethnicity," Journal of Development Economics, Elsevier, vol. 115(C), pages 32-44.
    7. Alfredo A. Romero, 2014. "Where do Moderation Terms Come from in Binary Choice Models?," Central European Journal of Economic Modelling and Econometrics, Central European Journal of Economic Modelling and Econometrics, vol. 6(1), pages 57-68, March.
    8. Bauernschuster, Stefan & Falck, Oliver & Heblich, Stephan, 2010. "Social capital access and entrepreneurship," Journal of Economic Behavior & Organization, Elsevier, vol. 76(3), pages 821-833, December.
    9. Nicos Nicolaou & Scott Shane, 2019. "Common genetic effects on risk-taking preferences and choices," Journal of Risk and Uncertainty, Springer, vol. 59(3), pages 261-279, December.
    10. Egon Franck & Erwin Verbeek & Stephan Nüesch, 2011. "Sentimental Preferences and the Organizational Regime of Betting Markets," Southern Economic Journal, John Wiley & Sons, vol. 78(2), pages 502-518, October.
    11. Zaporozhets, Vera & García-Valiñas, María & Kurz, Sascha, 2016. "Key drivers of EU budget allocation: Does power matter?," European Journal of Political Economy, Elsevier, vol. 43(C), pages 57-70.
    12. Andrei Bremzen & Elena Khokhlova & Anton Suvorov & Jeroen van de Ven, 2015. "Bad News: An Experimental Study on the Informational Effects Of Rewards," The Review of Economics and Statistics, MIT Press, vol. 97(1), pages 55-70, March.
    13. Susanne Prantl & Alexandra Spitz‐Oener, 2009. "How does entry regulation influence entry into self‐employment and occupational mobility?1," The Economics of Transition, The European Bank for Reconstruction and Development, vol. 17(4), pages 769-802, October.
    14. Chevassus-Lozza, Emmanuelle & Gaigné, Carl & Le Mener, Léo, 2013. "Does input trade liberalization boost downstream firms' exports? Theory and firm-level evidence," Journal of International Economics, Elsevier, vol. 90(2), pages 391-402.
    15. Dirk Bursian & Sven Fürth, 2015. "Trust Me! I am a European Central Banker," Journal of Money, Credit and Banking, Blackwell Publishing, vol. 47(8), pages 1503-1530, December.
    16. Efing, Matthias, 2015. "Arbitraging the Basel securitization framework: Evidence from German ABS investment," Discussion Papers 40/2015, Deutsche Bundesbank.
    17. Dienes, Christian, 2015. "Actions and intentions to pay for climate change mitigation: Environmental concern and the role of economic factors," Ecological Economics, Elsevier, vol. 109(C), pages 122-129.
    18. Annalisa Ferrando & Alexander Popov & Gregory F. Udell, 2019. "Do SMEs Benefit from Unconventional Monetary Policy and How? Microevidence from the Eurozone," Journal of Money, Credit and Banking, Blackwell Publishing, vol. 51(4), pages 895-928, June.
    19. Deka, Devajyoti, 2012. "The impacts of non-resident parking restrictions at commuter rail stations," Journal of Transport Geography, Elsevier, vol. 24(C), pages 451-461.
    20. Dickson, Lisa & Pender, Matea, 2013. "Do in-state tuition benefits affect the enrollment of non-citizens? Evidence from universities in Texas," Economics of Education Review, Elsevier, vol. 37(C), pages 126-137.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:bpj:erjour:v:2:y:2012:i:2:n:1. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Peter Golla (email available below). General contact details of provider: https://www.degruyter.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.